Details for gene set KEGG_ALZHEIMERS

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	LG
GeneSet	KEGG_ALZHEIMERS_DISEASE
Enrichment Score (ES)	0.38074696
Normalized Enrichment Score (NES)	1.4726322
Nominal p-value	0.0088626295
FDR q-value	0.22336806
FWER p-Value	0.953

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COX6A2	Cox6a2	3	4.063	0.0613	Yes
2	RYR3	Ryr3	38	3.221	0.1079	Yes
3	GRIN1	Grin1	102	2.719	0.1450	Yes
4	MME	Mme	246	2.231	0.1694	Yes
5	PSEN2	Psen2	441	1.857	0.1849	Yes
6	BID	Bid	542	1.724	0.2045	Yes
7	FAS	Fas	579	1.684	0.2277	Yes
8	SNCA	Snca	816	1.442	0.2342	Yes
9	APOE	Apoe	852	1.410	0.2533	Yes
10	ATP2A3	Atp2a3	923	1.350	0.2692	Yes
11	NDUFA4L2	Ndufa4l2	1121	1.210	0.2747	Yes
12	ATP2A1	Atp2a1	1354	1.073	0.2758	Yes
13	CASP7	Casp7	1487	1.011	0.2826	Yes
14	ITPR2	Itpr2	1579	0.974	0.2914	Yes
15	PLCB4	Plcb4	1596	0.969	0.3050	Yes
16	UQCRQ	Uqcrq	1648	0.955	0.3162	Yes
17	LPL	Lpl	1756	0.911	0.3230	Yes
18	CASP9	Casp9	2084	0.814	0.3141	Yes
19	COX5B	Cox5b	2152	0.799	0.3218	Yes
20	MT-CYB	mt-Cytb	2250	0.773	0.3272	Yes
21	TNFRSF1A	Tnfrsf1a	2584	0.672	0.3157	Yes
22	APP	App	2616	0.663	0.3237	Yes
23	COX8C	Cox8b	2685	0.646	0.3291	Yes
24	GRIN2D	Grin2d	2733	0.635	0.3357	Yes
25	CDK5R1	Cdk5r1	2744	0.632	0.3446	Yes
26	IDE	Ide	2809	0.617	0.3498	Yes
27	MAPT	Mapt	2823	0.613	0.3582	Yes
28	CDK5	Cdk5	2989	0.575	0.3562	Yes
29	NDUFB9	Ndufb9	2998	0.573	0.3643	Yes
30	COX7A1	Cox7a1	3057	0.561	0.3691	Yes
31	BAD	Bad	3217	0.532	0.3668	Yes
32	GAPDH	Gapdh	3254	0.525	0.3724	Yes
33	NDUFS7	Ndufs7	3362	0.504	0.3731	Yes
34	NDUFA1	Ndufa1	3395	0.498	0.3785	Yes
35	NDUFB6	Ndufb6	3814	0.432	0.3579	Yes
36	IL1B	Il1b	3859	0.432	0.3615	Yes
37	COX7B2	Cox7b2	4000	0.421	0.3588	Yes
38	NDUFS8	Ndufs8	4063	0.417	0.3611	Yes
39	MT-CO1	mt-Co1	4064	0.417	0.3674	Yes
40	PSEN1	Psen1	4089	0.412	0.3721	Yes
41	GRIN2C	Grin2c	4219	0.407	0.3699	Yes
42	FADD	Fadd	4262	0.401	0.3732	Yes
43	COX5A	Cox5a	4281	0.397	0.3780	Yes
44	CALM1	Calm1	4354	0.386	0.3792	Yes
45	ITPR3	Itpr3	4419	0.376	0.3807	Yes
46	APBB1	Apbb1	4798	0.312	0.3609	No
47	COX7A2L	Cox7a2l	4974	0.289	0.3539	No
48	CAPN1	Capn1	5003	0.286	0.3564	No
49	COX8A	Cox8a	5132	0.271	0.3522	No
50	NCSTN	Ncstn	5158	0.268	0.3546	No
51	NDUFA10	Ndufa10	5273	0.251	0.3510	No
52	COX4I1	Cox4i1	5301	0.248	0.3530	No
53	NDUFA5	Ndufa5	5352	0.242	0.3534	No
54	NDUFA2	Ndufa2	5361	0.240	0.3565	No
55	CAPN2	Capn2	5378	0.237	0.3591	No
56	CHP1	Chp1	5427	0.231	0.3594	No
57	NDUFV1	Ndufv1	5648	0.201	0.3482	No
58	MT-CO2	mt-Co2	5674	0.198	0.3495	No
59	APAF1	Apaf1	5738	0.190	0.3483	No
60	NDUFS6	Ndufs6	5849	0.174	0.3438	No
61	GSK3B	Gsk3b	5879	0.171	0.3445	No
62	NAE1	Nae1	5882	0.170	0.3470	No
63	NDUFB7	Ndufb7	5894	0.168	0.3488	No
64	NDUFB4	Ndufb4	6009	0.155	0.3437	No
65	NDUFS3	Ndufs3	6090	0.146	0.3408	No
66	NDUFA9	Ndufa9	6103	0.145	0.3422	No
67	CYC1	Cyc1	6122	0.143	0.3432	No
68	APH1A	Aph1a	6126	0.143	0.3451	No
69	UQCR10	Uqcr10	6139	0.141	0.3465	No
70	NDUFB5	Ndufb5	6160	0.139	0.3473	No
71	BACE1	Bace1	6298	0.124	0.3403	No
72	NDUFS5	Ndufs5	6319	0.122	0.3408	No
73	PLCB2	Plcb2	6348	0.118	0.3408	No
74	CASP8	Casp8	6359	0.117	0.3419	No
75	NDUFA6	Ndufa6	6414	0.110	0.3401	No
76	PPP3CC	Ppp3cc	6542	0.096	0.3333	No
77	CACNA1S	Cacna1s	6583	0.091	0.3320	No
78	COX7C	Cox7c	6805	0.065	0.3186	No
79	SDHB	Sdhb	6917	0.055	0.3123	No
80	NDUFB1	Ndufb1-ps	7008	0.045	0.3071	No
81	COX6A1	Cox6a1	7077	0.036	0.3032	No
82	SDHC	Sdhc	7086	0.036	0.3032	No
83	CALML3	Calml3	7106	0.034	0.3025	No
84	MAPK3	Mapk3	7199	0.024	0.2969	No
85	NDUFB3	Ndufb3	7356	0.007	0.2869	No
86	NDUFA8	Ndufa8	7412	0.002	0.2833	No
87	MT-ATP6	mt-Atp6	7555	0.000	0.2741	No
88	PPP3R2	Ppp3r2	7663	0.000	0.2671	No
89	TNF	Tnf	7693	0.000	0.2653	No
90	MT-CO3	mt-Co3	7729	0.000	0.2630	No
91	CACNA1F	Cacna1f	7745	0.000	0.2620	No
92	NDUFC1	Ndufc1	7937	-0.003	0.2496	No
93	NDUFS4	Ndufs4	8020	-0.010	0.2445	No
94	ATP5F1E	Atp5e	8023	-0.010	0.2445	No
95	UQCRB	Uqcrb	8025	-0.011	0.2446	No
96	NDUFA4	Ndufa4	8027	-0.011	0.2447	No
97	ATP5PD	Atp5h	8167	-0.025	0.2360	No
98	HSD17B10	Hsd17b10	8284	-0.034	0.2290	No
99	MAPK1	Mapk1	8316	-0.037	0.2275	No
100	NDUFB10	Ndufb10	8329	-0.039	0.2273	No
101	ERN1	Ern1	8591	-0.065	0.2114	No
102	ADAM10	Adam10	8611	-0.066	0.2111	No
103	NDUFS2	Ndufs2	8687	-0.073	0.2074	No
104	ATP2A2	Atp2a2	8693	-0.074	0.2082	No
105	NDUFS1	Ndufs1	8719	-0.076	0.2077	No
106	NOS1	Nos1	8757	-0.080	0.2065	No
107	COX4I2	Cox4i2	8807	-0.084	0.2046	No
108	EIF2AK3	Eif2ak3	8881	-0.090	0.2012	No
109	COX6C	Cox6c	8935	-0.096	0.1992	No
110	LRP1	Lrp1	9056	-0.110	0.1931	No
111	ATP5F1D	Atp5d	9134	-0.118	0.1898	No
112	COX6B1	Cox6b1	9141	-0.119	0.1913	No
113	ATF6	Atf6	9163	-0.122	0.1917	No
114	ATP5PF	Atp5j	9296	-0.134	0.1852	No
115	ATP5F1B	Atp5b	9370	-0.141	0.1826	No
116	CYCS	Cycs	9414	-0.145	0.1820	No
117	NDUFA3	Ndufa3	9616	-0.166	0.1714	No
118	PLCB3	Plcb3	9618	-0.166	0.1739	No
119	ATP5F1C	Atp5c1	9706	-0.174	0.1708	No
120	CALM3	Calm3	9742	-0.178	0.1713	No
121	NDUFV3	Ndufv3	9809	-0.184	0.1698	No
122	PPP3CA	Ppp3ca	10018	-0.206	0.1593	No
123	CALM2	Calm2	10048	-0.209	0.1606	No
124	ATP5MC3	Atp5g3	10054	-0.209	0.1635	No
125	NDUFV2	Ndufv2	10193	-0.222	0.1579	No
126	BACE2	Bace2	10286	-0.232	0.1554	No
127	UQCRC2	Uqcrc2	10364	-0.240	0.1540	No
128	COX7A2	Cox7a2	10673	-0.273	0.1381	No
129	UQCRC1	Uqcrc1	10805	-0.287	0.1340	No
130	NDUFB2	Ndufb2	10880	-0.294	0.1336	No
131	ATP5F1A	Atp5a1	11636	-0.380	0.0903	No
132	PPP3CB	Ppp3cb	11662	-0.384	0.0945	No
133	NDUFAB1	Ndufab1	11683	-0.388	0.0990	No
134	UQCRFS1	Uqcrfs1	12508	-0.475	0.0527	No
135	COX7B	Cox7b	12640	-0.494	0.0516	No
136	CHP2	Chp2	12674	-0.499	0.0570	No
137	GRIN2B	Grin2b	12688	-0.500	0.0638	No
138	GRIN2A	Grin2a	12999	-0.553	0.0520	No
139	ITPR1	Itpr1	13613	-0.701	0.0227	No
140	CACNA1D	Cacna1d	13877	-0.781	0.0174	No
141	COX6B2	Cox6b2	14123	-0.857	0.0145	No
142	ADAM17	Adam17	14259	-0.905	0.0194	No
143	CASP3	Casp3	14471	-1.004	0.0209	No
144	PLCB1	Plcb1	15032	-1.546	0.0079	No
145	CACNA1C	Cacna1c	15057	-1.590	0.0304	No