Details for gene set KEGG_AXON_GUIDANCE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	LG
GeneSet	KEGG_AXON_GUIDANCE
Enrichment Score (ES)	0.42586383
Normalized Enrichment Score (NES)	1.6082749
Nominal p-value	0.0015174507
FDR q-value	0.122683264
FWER p-Value	0.6

Fig 1: Enrichment plot: KEGG_AXON_GUIDANCE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SRGAP1	Srgap1			48	3.094	0.0296	Yes
2	EPHA4	Epha4			56	3.037	0.0613	Yes
3	ROBO2	Robo2			97	2.750	0.0878	Yes
4	SEMA3E	Sema3e			135	2.563	0.1125	Yes
5	ROBO3	Robo3			143	2.526	0.1387	Yes
6	EPHB2	Ephb2			214	2.318	0.1587	Yes
7	NTN4	Ntn4			239	2.256	0.1810	Yes
8	SEMA3C	Sema3c			249	2.214	0.2038	Yes
9	L1CAM	L1cam			375	1.967	0.2165	Yes
10	ROBO1	Robo1			418	1.897	0.2338	Yes
11	SEMA4D	Sema4d			456	1.837	0.2509	Yes
12	SEMA6C	Sema6c			524	1.736	0.2649	Yes
13	CXCL12	Cxcl12			553	1.714	0.2812	Yes
14	ABLIM2	Ablim2			592	1.660	0.2963	Yes
15	ABLIM3	Ablim3			643	1.602	0.3100	Yes
16	PLXNC1	Plxnc1			856	1.408	0.3111	Yes
17	LIMK1	Limk1			950	1.334	0.3192	Yes
18	EFNA3	Efna3			985	1.310	0.3308	Yes
19	EPHA7	Epha7			1041	1.269	0.3407	Yes
20	RHOD	Rhod			1110	1.217	0.3491	Yes
21	PAK6	Pak6			1283	1.107	0.3497	Yes
22	ABLIM1	Ablim1			1300	1.098	0.3602	Yes
23	EFNB3	Efnb3			1356	1.072	0.3680	Yes
24	FYN	Fyn			1575	0.976	0.3642	Yes
25	SLIT1	Slit1			1593	0.971	0.3733	Yes
26	UNC5D	Unc5d			1629	0.960	0.3812	Yes
27	GNAI1	Gnai1			1736	0.921	0.3841	Yes
28	PAK3	Pak3			1844	0.880	0.3864	Yes
29	CXCR4	Cxcr4			1862	0.875	0.3946	Yes
30	EPHB4	Ephb4			1902	0.862	0.4012	Yes
31	SEMA3B	Sema3b			2070	0.819	0.3990	Yes
32	NCK2	Nck2			2082	0.814	0.4069	Yes
33	HRAS	Hras			2180	0.791	0.4089	Yes
34	SEMA4F	Sema4f			2253	0.772	0.4124	Yes
35	RAC3	Rac3			2306	0.753	0.4170	Yes
36	SEMA3D	Sema3d			2405	0.726	0.4183	Yes
37	CFL2	Cfl2			2408	0.724	0.4259	Yes
38	DPYSL5	Dpysl5			2570	0.674	0.4225	No
39	SRGAP3	Srgap3			2725	0.636	0.4193	No
40	EFNA2	Efna2			2887	0.599	0.4152	No
41	CDK5	Cdk5			2989	0.575	0.4147	No
42	EFNA4	Efna4			3138	0.544	0.4108	No
43	SEMA4A	Sema4a			3382	0.500	0.4003	No
44	RND1	Rnd1			3394	0.498	0.4049	No
45	NRAS	Nras			3680	0.455	0.3912	No
46	EPHB1	Ephb1			3779	0.438	0.3895	No
47	NFATC1	Nfatc1			3783	0.437	0.3939	No
48	UNC5A	Unc5a			3903	0.427	0.3907	No
49	PLXNA2	Plxna2			4066	0.416	0.3846	No
50	FES	Fes			4508	0.360	0.3597	No
51	PLXNA1	Plxna1			4791	0.313	0.3447	No
52	RAC2	Rac2			4827	0.309	0.3457	No
53	EPHA2	Epha2			4921	0.295	0.3428	No
54	SEMA3G	Sema3g			4936	0.294	0.3450	No
55	KRAS	Kras			5181	0.266	0.3320	No
56	SEMA3F	Sema3f			5348	0.242	0.3238	No
57	EFNA1	Efna1			5353	0.241	0.3260	No
58	LRRC4C	Lrrc4c			5359	0.240	0.3283	No
59	CHP1	Chp1			5427	0.231	0.3263	No
60	PLXNB2	Plxnb2			5651	0.200	0.3140	No
61	PLXNB1	Plxnb1			5806	0.180	0.3059	No
62	GSK3B	Gsk3b			5879	0.171	0.3030	No
63	EFNB1	Efnb1			5926	0.166	0.3018	No
64	PPP3CC	Ppp3cc			6542	0.096	0.2629	No
65	EPHB3	Ephb3			6654	0.083	0.2565	No
66	CFL1	Cfl1			6669	0.082	0.2565	No
67	RHOA	Rhoa			6904	0.056	0.2419	No
68	GNAI3	Gnai3			7030	0.042	0.2342	No
69	LIMK2	Limk2			7184	0.025	0.2245	No
70	RGS3	Rgs3			7192	0.024	0.2243	No
71	MAPK3	Mapk3			7199	0.024	0.2242	No
72	SEMA5B	Sema5b			7537	0.000	0.2023	No
73	PPP3R2	Ppp3r2			7663	0.000	0.1942	No
74	PAK5	Pak7			7772	0.000	0.1872	No
75	NFATC3	Nfatc3			8019	-0.010	0.1713	No
76	SLIT2	Slit2			8229	-0.029	0.1581	No
77	SEMA6A	Sema6a			8280	-0.034	0.1552	No
78	EPHA8	Epha8			8303	-0.036	0.1541	No
79	SEMA6B	Sema6b			8309	-0.036	0.1542	No
80	MAPK1	Mapk1			8316	-0.037	0.1542	No
81	GNAI2	Gnai2			8727	-0.077	0.1284	No
82	CDC42	Cdc42			9384	-0.142	0.0873	No
83	EPHA3	Epha3			9528	-0.157	0.0796	No
84	PAK2	Pak2			9749	-0.178	0.0672	No
85	ROCK1	Rock1			9810	-0.184	0.0653	No
86	PLXNB3	Plxnb3			9896	-0.193	0.0618	No
87	PAK4	Pak4			9936	-0.197	0.0614	No
88	PPP3CA	Ppp3ca			10018	-0.206	0.0583	No
89	NCK1	Nck1			10145	-0.218	0.0524	No
90	PLXNA3	Plxna3			10284	-0.232	0.0459	No
91	EFNB2	Efnb2			10319	-0.236	0.0462	No
92	ABL1	Abl1			10496	-0.253	0.0374	No
93	ROCK2	Rock2			11123	-0.321	0.0002	No
94	ARHGEF12	Arhgef12			11177	-0.328	0.0002	No
95	EFNA5	Efna5			11199	-0.330	0.0023	No
96	ITGB1	Itgb1			11361	-0.348	-0.0045	No
97	RAC1	Rac1			11450	-0.360	-0.0064	No
98	DCC	Dcc			11575	-0.373	-0.0105	No
99	EPHB6	Ephb6			11626	-0.379	-0.0097	No
100	PPP3CB	Ppp3cb			11662	-0.384	-0.0079	No
101	EPHA6	Epha6			11981	-0.418	-0.0241	No
102	PTK2	Ptk2			12178	-0.432	-0.0323	No
103	UNC5C	Unc5c			12318	-0.445	-0.0366	No
104	NFATC4	Nfatc4			12649	-0.495	-0.0528	No
105	CHP2	Chp2			12674	-0.499	-0.0491	No
106	NTN1	Ntn1			12826	-0.521	-0.0534	No
107	NFAT5	Nfat5			12936	-0.538	-0.0548	No
108	PAK1	Pak1			13205	-0.599	-0.0659	No
109	SEMA4G	Sema4g			13289	-0.618	-0.0647	No
110	SEMA6D	Sema6d			13498	-0.667	-0.0712	No
111	DPYSL2	Dpysl2			13616	-0.702	-0.0713	No
112	NRP1	Nrp1			13680	-0.720	-0.0678	No
113	SEMA4B	Sema4b			13704	-0.729	-0.0616	No
114	MET	Met			13861	-0.774	-0.0635	No
115	SLIT3	Slit3			14245	-0.900	-0.0789	No
116	SEMA3A	Sema3a			14254	-0.903	-0.0699	No
117	SEMA4C	Sema4c			14288	-0.920	-0.0623	No
118	NTN3	Ntn3			14343	-0.942	-0.0558	No
119	UNC5B	Unc5b			14545	-1.051	-0.0578	No
120	NTNG1	Ntng1			14647	-1.121	-0.0525	No
121	NFATC2	Nfatc2			14873	-1.340	-0.0529	No
122	RASA1	Rasa1			14886	-1.350	-0.0394	No
123	EPHA5	Epha5			14912	-1.382	-0.0264	No
124	SEMA5A	Sema5a			14920	-1.391	-0.0122	No
125	NGEF	Ngef			14925	-1.396	0.0023	No
126	SEMA7A	Sema7a			15078	-1.630	0.0097	No
127	EPHA1	Epha1			15181	-1.820	0.0223	No

Fig 2: KEGG_AXON_GUIDANCE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_AXON_GUIDANCE: Random ES distribution   
Gene set null distribution of ES for KEGG_AXON_GUIDANCE