Details for gene set KEGG_GAP_JUNCTION[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_GAP_JUNCTION
Enrichment Score (ES)	-0.36386806
Normalized Enrichment Score (NES)	-1.3827095
Nominal p-value	0.0259366
FDR q-value	0.27989718
FWER p-Value	0.981

Fig 1: Enrichment plot: KEGG_GAP_JUNCTION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ADCY1	Adcy1			366	1.982	0.0156	No
2	ADRB1	Adrb1			647	1.600	0.0291	No
3	GJA1	Gja6			660	1.594	0.0599	No
4	PRKCG	Prkcg			996	1.303	0.0640	No
5	TUBA4A	Tuba4a			1072	1.243	0.0838	No
6	ITPR2	Itpr2			1579	0.974	0.0704	No
7	PLCB4	Plcb4			1596	0.969	0.0885	No
8	GNAI1	Gnai1			1736	0.921	0.0978	No
9	PDGFB	Pdgfb			2135	0.802	0.0879	No
10	HRAS	Hras			2180	0.791	0.1007	No
11	TUBB2A	Tubb2a			2269	0.766	0.1102	No
12	MAPK7	Mapk7			2371	0.734	0.1182	No
13	ADCY9	Adcy9			2390	0.729	0.1314	No
14	ADCY3	Adcy3			2687	0.646	0.1251	No
15	PDGFA	Pdgfa			3028	0.566	0.1143	No
16	GUCY1A2	Gucy1a2			3255	0.524	0.1100	No
17	NRAS	Nras			3680	0.455	0.0916	No
18	TUBAL3	Tubal3			3855	0.432	0.0889	No
19	ITPR3	Itpr3			4419	0.376	0.0599	No
20	TUBB4A	Tubb4a			4517	0.359	0.0607	No
21	GRM5	Grm5			4660	0.333	0.0581	No
22	GNAS	Gnas			5004	0.286	0.0416	No
23	KRAS	Kras			5181	0.266	0.0355	No
24	ADCY6	Adcy6			5613	0.207	0.0117	No
25	HTR2A	Htr2a			6033	0.152	-0.0125	No
26	PLCB2	Plcb2			6348	0.118	-0.0304	No
27	ADCY2	Adcy2			6832	0.063	-0.0605	No
28	ADCY4	Adcy4			6834	0.063	-0.0593	No
29	CSNK1D	Csnk1d			6985	0.048	-0.0680	No
30	GNAI3	Gnai3			7030	0.042	-0.0700	No
31	MAPK3	Mapk3			7199	0.024	-0.0805	No
32	DRD1	Drd1			8002	-0.009	-0.1322	No
33	ADCY5	Adcy5			8247	-0.030	-0.1474	No
34	MAPK1	Mapk1			8316	-0.037	-0.1511	No
35	TUBB2B	Tubb2b			8442	-0.048	-0.1582	No
36	GRB2	Grb2			8518	-0.055	-0.1620	No
37	RAF1	Raf1			8539	-0.058	-0.1621	No
38	GNAI2	Gnai2			8727	-0.077	-0.1727	No
39	MAP3K2	Map3k2			8902	-0.092	-0.1821	No
40	GUCY1B1	Gucy1b1			8936	-0.096	-0.1824	No
41	GNA11	Gna11			9020	-0.106	-0.1856	No
42	SOS2	Sos2			9170	-0.122	-0.1929	No
43	TUBB1	Tubb1			9345	-0.138	-0.2014	No
44	HTR2B	Htr2b			9391	-0.143	-0.2015	No
45	SOS1	Sos1			9428	-0.146	-0.2009	No
46	LPAR1	Lpar1			9492	-0.152	-0.2020	No
47	TUBA1B	Tuba1b			9495	-0.153	-0.1991	No
48	PLCB3	Plcb3			9618	-0.166	-0.2037	No
49	TUBA1A	Tuba1a			10027	-0.206	-0.2260	No
50	MAP2K5	Map2k5			10063	-0.211	-0.2241	No
51	PRKACB	Prkacb			10431	-0.249	-0.2430	No
52	TUBA1C	Tuba1c			10983	-0.305	-0.2726	No
53	TJP1	Tjp1			11113	-0.321	-0.2746	No
54	PDGFC	Pdgfc			11255	-0.336	-0.2770	No
55	CDK1	Cdk1			11707	-0.390	-0.2985	No
56	PRKACA	Prkaca			12054	-0.424	-0.3125	No
57	PDGFD	Pdgfd			12217	-0.437	-0.3143	No
58	SRC	Src			12330	-0.446	-0.3128	No
59	TUBA3D	Tuba3b			12352	-0.449	-0.3052	No
60	TUBB	Tubb5			13072	-0.569	-0.3405	No
61	MAP2K1	Map2k1			13134	-0.581	-0.3329	No
62	ITPR1	Itpr1			13613	-0.701	-0.3500	Yes
63	TUBB4B	Tubb4b			13618	-0.702	-0.3363	Yes
64	GRM1	Grm1			13914	-0.793	-0.3397	Yes
65	GJD2	Gjd2			14015	-0.825	-0.3299	Yes
66	TUBB6	Tubb6			14085	-0.844	-0.3176	Yes
67	EGFR	Egfr			14176	-0.870	-0.3062	Yes
68	TUBA8	Tuba8			14235	-0.897	-0.2922	Yes
69	GUCY1A1	Gucy1a1			14317	-0.932	-0.2790	Yes
70	ADCY7	Adcy7			14683	-1.147	-0.2799	Yes
71	PRKCA	Prkca			14737	-1.199	-0.2596	Yes
72	PDGFRB	Pdgfrb			14829	-1.288	-0.2399	Yes
73	EGF	Egf			14924	-1.396	-0.2184	Yes
74	PLCB1	Plcb1			15032	-1.546	-0.1947	Yes
75	PDGFRA	Pdgfra			15163	-1.787	-0.1677	Yes
76	PRKG2	Prkg2			15189	-1.835	-0.1329	Yes
77	PRKG1	Prkg1			15377	-2.412	-0.0973	Yes
78	ADCY8	Adcy8			15381	-2.433	-0.0492	Yes
79	PRKCB	Prkcb			15461	-2.954	0.0041	Yes

Fig 2: KEGG_GAP_JUNCTION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_GAP_JUNCTION: Random ES distribution   
Gene set null distribution of ES for KEGG_GAP_JUNCTION