Details for gene set KEGG_LYSOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	LG
GeneSet	KEGG_LYSOSOME
Enrichment Score (ES)	0.5270431
Normalized Enrichment Score (NES)	1.9806774
Nominal p-value	0.0
FDR q-value	0.0030487445
FWER p-Value	0.003

Fig 1: Enrichment plot: KEGG_LYSOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NEU1	Neu1			139	2.549	0.0204	Yes
2	CTSW	Ctsw			335	2.032	0.0313	Yes
3	GLA	Gla			345	2.018	0.0540	Yes
4	GBA	Gba			486	1.793	0.0656	Yes
5	SORT1	Sort1			502	1.763	0.0850	Yes
6	MCOLN1	Mcoln1			509	1.759	0.1050	Yes
7	MANBA	Manba			513	1.755	0.1250	Yes
8	LAMP1	Lamp1			544	1.721	0.1430	Yes
9	HEXB	Hexb			568	1.696	0.1611	Yes
10	ATP6V0B	Atp6v0b			684	1.564	0.1717	Yes
11	CTNS	Ctns			715	1.534	0.1875	Yes
12	ATP6V0D1	Atp6v0d1			720	1.529	0.2049	Yes
13	CTSA	Ctsa			787	1.459	0.2175	Yes
14	NPC1	Npc1			822	1.439	0.2319	Yes
15	GNPTG	Gnptg			853	1.409	0.2462	Yes
16	TPP1	Tpp1			869	1.398	0.2614	Yes
17	SLC17A5	Slc17a5			935	1.344	0.2727	Yes
18	GNS	Gns			940	1.341	0.2879	Yes
19	ATP6AP1	Atp6ap1			994	1.304	0.2995	Yes
20	SGSH	Sgsh			1014	1.287	0.3132	Yes
21	SCARB2	Scarb2			1035	1.274	0.3266	Yes
22	ACP5	Acp5			1128	1.206	0.3346	Yes
23	NAGA	Naga			1167	1.174	0.3457	Yes
24	LAMP2	Lamp2			1233	1.133	0.3545	Yes
25	MAN2B1	Man2b1			1244	1.126	0.3669	Yes
26	GAA	Gaa			1255	1.120	0.3792	Yes
27	LIPA	Lipa			1295	1.101	0.3894	Yes
28	GALC	Galc			1298	1.099	0.4020	Yes
29	GGA2	Gga2			1326	1.085	0.4127	Yes
30	HYAL1	Hyal1			1335	1.080	0.4247	Yes
31	DNASE2	Dnase2a			1376	1.062	0.4344	Yes
32	NAGPA	Nagpa			1401	1.052	0.4450	Yes
33	TCIRG1	Tcirg1			1552	0.985	0.4466	Yes
34	ARSG	Arsg			1585	0.972	0.4558	Yes
35	SUMF1	Sumf1			1598	0.968	0.4662	Yes
36	ATP6V1H	Atp6v1h			1666	0.945	0.4728	Yes
37	ASAH1	Asah1			1688	0.937	0.4822	Yes
38	IDUA	Idua			1753	0.911	0.4886	Yes
39	NPC2	Npc2			1978	0.839	0.4838	Yes
40	NAGLU	Naglu			2088	0.812	0.4861	Yes
41	PSAP	Psap			2143	0.801	0.4918	Yes
42	PLA2G15	Pla2g15			2333	0.745	0.4882	Yes
43	ATP6V0C	Atp6v0c			2362	0.737	0.4949	Yes
44	SLC11A2	Slc11a2			2446	0.711	0.4977	Yes
45	AP3D1	Ap3d1			2458	0.707	0.5052	Yes
46	GUSB	Gusb			2612	0.665	0.5029	Yes
47	CD63	Cd63			2633	0.659	0.5092	Yes
48	HGSNAT	Hgsnat			2696	0.644	0.5127	Yes
49	GM2A	Gm2a			3102	0.551	0.4928	Yes
50	CLTB	Cltb			3143	0.544	0.4964	Yes
51	ATP6V0A1	Atp6v0a1			3146	0.543	0.5026	Yes
52	ATP6V0A2	Atp6v0a2			3190	0.536	0.5060	Yes
53	ATP6V0A4	Atp6v0a4			3241	0.528	0.5088	Yes
54	ARSA	Arsa			3403	0.497	0.5041	Yes
55	CTSB	Ctsb			3442	0.491	0.5073	Yes
56	SMPD1	Smpd1			3444	0.490	0.5129	Yes
57	LAPTM4B	Laptm4b			3512	0.483	0.5142	Yes
58	CTSO	Ctso			3590	0.472	0.5146	Yes
59	ARSB	Arsb			3608	0.469	0.5189	Yes
60	GNPTAB	Gnptab			3634	0.463	0.5227	Yes
61	LAPTM4A	Laptm4a			3784	0.437	0.5181	Yes
62	AGA	Aga			3792	0.435	0.5226	Yes
63	ENTPD4	Entpd4b			3826	0.432	0.5255	Yes
64	AP3M2	Ap3m2			3912	0.426	0.5249	Yes
65	DNASE2B	Dnase2b			4026	0.421	0.5224	Yes
66	ACP2	Acp2			4071	0.415	0.5243	Yes
67	AP1M2	Ap1m2			4134	0.407	0.5250	Yes
68	GGA1	Gga1			4261	0.401	0.5215	Yes
69	CLTA	Clta			4277	0.398	0.5251	Yes
70	FUCA1	Fuca1			4318	0.392	0.5270	Yes
71	CLTC	Cltc			4498	0.362	0.5196	No
72	AP3M1	Ap3m1			4514	0.359	0.5228	No
73	PPT1	Ppt1			4633	0.338	0.5190	No
74	CD164	Cd164			4964	0.290	0.5010	No
75	AP3S2	Ap3s2			5296	0.249	0.4824	No
76	AP4S1	Ap4s1			5667	0.198	0.4607	No
77	GGA3	Gga3			5847	0.174	0.4511	No
78	AP1M1	Ap1m1			5943	0.164	0.4468	No
79	M6PR	M6pr			6252	0.130	0.4283	No
80	CTSZ	Ctsz			6296	0.124	0.4270	No
81	PPT2	Ppt2			6388	0.113	0.4224	No
82	AP4E1	Ap4e1			6519	0.098	0.4151	No
83	AP3B1	Ap3b1			6817	0.065	0.3965	No
84	ABCA2	Abca2			7103	0.034	0.3785	No
85	AP3S1	Ap3s1			7117	0.034	0.3780	No
86	GLB1	Glb1			7216	0.021	0.3719	No
87	CTSG	Ctsg			7242	0.019	0.3705	No
88	CTSK	Ctsk			7383	0.006	0.3615	No
89	IGF2R	Igf2r			7391	0.004	0.3611	No
90	CTSS	Ctss			7657	0.000	0.3439	No
91	AP1S1	Ap1s1			8330	-0.039	0.3007	No
92	NAPSA	Napsa			8385	-0.043	0.2977	No
93	LGMN	Lgmn			8674	-0.072	0.2799	No
94	AP1S2	Ap1s2			8718	-0.076	0.2780	No
95	AP3B2	Ap3b2			8900	-0.092	0.2673	No
96	MFSD8	Mfsd8			9143	-0.119	0.2530	No
97	AP1B1	Ap1b1			9255	-0.130	0.2473	No
98	GALNS	Galns			9915	-0.195	0.2068	No
99	AP4M1	Ap4m1			10254	-0.229	0.1875	No
100	CTSE	Ctse			10850	-0.291	0.1522	No
101	AP1G1	Ap1g1			10957	-0.302	0.1489	No
102	ABCB9	Abcb9			12581	-0.486	0.0492	No
103	CTSH	Ctsh			12689	-0.500	0.0480	No
104	PSAPL1	Psapl1			12782	-0.512	0.0480	No
105	AP1S3	Ap1s3			13056	-0.565	0.0368	No
106	SLC11A1	Slc11a1			14401	-0.972	-0.0392	No
107	CTSC	Ctsc			14438	-0.988	-0.0301	No
108	CTSF	Ctsf			14892	-1.362	-0.0437	No
109	AP4B1	Ap4b1			15165	-1.790	-0.0407	No
110	ATP6V0D2	Atp6v0d2			15389	-2.504	-0.0263	No
111	LAPTM5	Laptm5			15466	-3.031	0.0038	No

Fig 2: KEGG_LYSOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_LYSOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_LYSOSOME