Details for gene set KEGG_MELANOMA[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_MELANOMA
Enrichment Score (ES)	-0.41178805
Normalized Enrichment Score (NES)	-1.5119929
Nominal p-value	0.012787724
FDR q-value	0.21055491
FWER p-Value	0.775

Fig 1: Enrichment plot: KEGG_MELANOMA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FGF22	Fgf22			545	1.720	0.0078	No
2	FGF17	Fgf17			646	1.600	0.0414	No
3	FGF5	Fgf5			901	1.373	0.0593	No
4	FGF6	Fgf6			1942	0.850	0.0133	No
5	FGF11	Fgf11			2121	0.805	0.0220	No
6	PDGFB	Pdgfb			2135	0.802	0.0412	No
7	HRAS	Hras			2180	0.791	0.0582	No
8	PDGFA	Pdgfa			3028	0.566	0.0176	No
9	PIK3CG	Pik3cg			3162	0.541	0.0225	No
10	BAD	Bad			3217	0.532	0.0323	No
11	E2F1	E2f1			3586	0.473	0.0204	No
12	NRAS	Nras			3680	0.455	0.0257	No
13	PIK3R5	Pik3r5			4080	0.414	0.0103	No
14	FGF18	Fgf18			4265	0.401	0.0084	No
15	PTEN	Pten			4496	0.362	0.0026	No
16	CDK4	Cdk4			4753	0.318	-0.0060	No
17	RB1	Rb1			4767	0.317	0.0011	No
18	E2F2	E2f2			5087	0.275	-0.0126	No
19	PIK3CD	Pik3cd			5095	0.274	-0.0062	No
20	KRAS	Kras			5181	0.266	-0.0051	No
21	FGF19	Fgf15			5398	0.234	-0.0132	No
22	CDKN1A	Cdkn1a			5579	0.211	-0.0195	No
23	MDM2	Mdm2			5688	0.197	-0.0216	No
24	CDK6	Cdk6			5902	0.167	-0.0312	No
25	ARAF	Araf			6005	0.156	-0.0339	No
26	FGF9	Fgf9			6060	0.149	-0.0336	No
27	FGF10	Fgf10			6700	0.078	-0.0730	No
28	E2F3	E2f3			6774	0.069	-0.0760	No
29	FGF7	Fgf7			6940	0.053	-0.0853	No
30	PIK3CB	Pik3cb			7007	0.045	-0.0885	No
31	AKT2	Akt2			7049	0.039	-0.0901	No
32	MAPK3	Mapk3			7199	0.024	-0.0992	No
33	AKT1	Akt1			8293	-0.035	-0.1690	No
34	MAPK1	Mapk1			8316	-0.037	-0.1695	No
35	RAF1	Raf1			8539	-0.058	-0.1824	No
36	BRAF	Braf			9178	-0.123	-0.2206	No
37	CDH1	Cdh1			9823	-0.185	-0.2576	No
38	TP53	Trp53			9983	-0.202	-0.2628	No
39	FGF12	Fgf12			10089	-0.213	-0.2643	No
40	FGF23	Fgf23			10529	-0.257	-0.2862	No
41	CCND1	Ccnd1			10950	-0.301	-0.3058	No
42	FGFR1	Fgfr1			11219	-0.332	-0.3149	No
43	PDGFC	Pdgfc			11255	-0.336	-0.3087	No
44	IGF1R	Igf1r			11788	-0.400	-0.3331	No
45	FGF2	Fgf2			11816	-0.404	-0.3247	No
46	PDGFD	Pdgfd			12217	-0.437	-0.3397	No
47	AKT3	Akt3			12618	-0.490	-0.3533	No
48	PIK3R1	Pik3r1			12760	-0.509	-0.3497	No
49	MAP2K1	Map2k1			13134	-0.581	-0.3592	No
50	PIK3CA	Pik3ca			13327	-0.625	-0.3560	No
51	MET	Met			13861	-0.774	-0.3711	No
52	EGFR	Egfr			14176	-0.870	-0.3696	No
53	PDGFRB	Pdgfrb			14829	-1.288	-0.3795	Yes
54	EGF	Egf			14924	-1.396	-0.3507	Yes
55	FGF21	Fgf21			14929	-1.400	-0.3159	Yes
56	FGF14	Fgf14			15115	-1.689	-0.2856	Yes
57	PDGFRA	Pdgfra			15163	-1.787	-0.2439	Yes
58	MITF	Mitf			15301	-2.140	-0.1992	Yes
59	IGF1	Igf1			15412	-2.616	-0.1409	Yes
60	FGF1	Fgf1			15443	-2.849	-0.0715	Yes
61	HGF	Hgf			15472	-3.068	0.0034	Yes

Fig 2: KEGG_MELANOMA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_MELANOMA: Random ES distribution   
Gene set null distribution of ES for KEGG_MELANOMA