Details for gene set KEGG_SPLICEOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#LG_versus_HG.phenotype.cls#LG_versus_HG_repos
Phenotype	phenotype.cls#LG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_SPLICEOSOME
Enrichment Score (ES)	-0.42162797
Normalized Enrichment Score (NES)	-1.6674242
Nominal p-value	0.0
FDR q-value	0.14665551
FWER p-Value	0.323

Fig 1: Enrichment plot: KEGG_SPLICEOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RBM8A	Rbm8a			1359	1.070	-0.0571	No
2	SNRPA1	Snrpa1			3775	0.440	-0.2010	No
3	TXNL4A	Txnl4a			4331	0.390	-0.2257	No
4	BCAS2	Bcas2			4344	0.387	-0.2152	No
5	SNRPF	Snrpf			4395	0.380	-0.2074	No
6	SNRNP27	Snrnp27			4919	0.296	-0.2328	No
7	USP39	Usp39			5016	0.285	-0.2307	No
8	SF3B5	Sf3b5			5055	0.280	-0.2251	No
9	CCDC12	Ccdc12			5414	0.232	-0.2415	No
10	ZMAT2	Zmat2			5887	0.169	-0.2673	No
11	BUD31	Bud31			5984	0.158	-0.2689	No
12	PRPF31	Prpf31			6008	0.156	-0.2659	No
13	SF3B6	Sf3b6			6063	0.149	-0.2651	No
14	RBMX	Rbmx			6116	0.144	-0.2643	No
15	PHF5A	Phf5a			6219	0.133	-0.2670	No
16	DHX16	Dhx16			6434	0.108	-0.2778	No
17	CWC15	Cwc15			6565	0.093	-0.2835	No
18	PRPF3	Prpf3			6664	0.082	-0.2875	No
19	PRPF38A	Prpf38a			6678	0.080	-0.2860	No
20	SLU7	Slu7			6850	0.062	-0.2953	No
21	LSM7	Lsm7			6883	0.058	-0.2957	No
22	SMNDC1	Smndc1			6982	0.048	-0.3006	No
23	LSM2	Lsm2			7088	0.036	-0.3064	No
24	U2AF2	U2af2			7211	0.022	-0.3137	No
25	HSPA2	Hspa2			7235	0.019	-0.3146	No
26	SF3B2	Sf3b2			7355	0.007	-0.3221	No
27	U2SURP	U2surp			8262	-0.032	-0.3800	No
28	SF3A2	Sf3a2			8292	-0.035	-0.3809	No
29	CHERP	Cherp			8314	-0.037	-0.3812	No
30	RBM25	Rbm25			8369	-0.043	-0.3834	No
31	PUF60	Puf60			8452	-0.049	-0.3873	No
32	SF3B4	Sf3b4			8485	-0.052	-0.3879	No
33	RBM22	Rbm22			8522	-0.055	-0.3886	No
34	DDX39B	Ddx39b			8554	-0.059	-0.3889	No
35	ALYREF	4931428L18Rik			8612	-0.066	-0.3907	No
36	HSPA8	Hspa8			8667	-0.071	-0.3921	No
37	THOC1	Thoc1			8709	-0.075	-0.3926	No
38	DDX23	Ddx23			8774	-0.081	-0.3944	No
39	SNRPC	Snrpc			8784	-0.082	-0.3926	No
40	PQBP1	Pqbp1			8792	-0.083	-0.3906	No
41	LSM4	Lsm4			8913	-0.093	-0.3957	No
42	SNRPB	Snrpb			8924	-0.094	-0.3936	No
43	PPIL1	Ppil1			8961	-0.099	-0.3931	No
44	MAGOH	Magoh			8962	-0.099	-0.3902	No
45	SNU13	Snu13			9032	-0.108	-0.3915	No
46	PLRG1	Plrg1			9055	-0.110	-0.3898	No
47	SF3B3	Sf3b3			9217	-0.126	-0.3965	No
48	SNRNP200	Snrnp200			9294	-0.134	-0.3976	No
49	PCBP1	Pcbp1			9354	-0.139	-0.3974	No
50	SF3A1	Sf3a1			9404	-0.144	-0.3964	No
51	RBM17	Rbm17			9652	-0.170	-0.4075	No
52	SYF2	Syf2			9700	-0.174	-0.4055	No
53	LSM8	Lsm8			9950	-0.198	-0.4159	Yes
54	DHX38	Dhx38			9955	-0.199	-0.4104	Yes
55	DDX46	Ddx46			10031	-0.207	-0.4092	Yes
56	TRA2B	Tra2b			10082	-0.212	-0.4063	Yes
57	DDX5	Ddx5			10188	-0.222	-0.4067	Yes
58	LSM6	Lsm6			10204	-0.223	-0.4012	Yes
59	PRPF19	Prpf19			10252	-0.229	-0.3976	Yes
60	PRPF8	Prpf8			10271	-0.230	-0.3921	Yes
61	CRNKL1	Crnkl1			10272	-0.231	-0.3854	Yes
62	MAGOHB	Magohb			10454	-0.250	-0.3899	Yes
63	PRPF4	Prpf4			10477	-0.252	-0.3840	Yes
64	EFTUD2	Eftud2			10483	-0.253	-0.3770	Yes
65	PRPF40A	Prpf40a			10498	-0.254	-0.3705	Yes
66	DHX8	Dhx8			10528	-0.257	-0.3649	Yes
67	SNRPD3	Snrpd3			10578	-0.263	-0.3605	Yes
68	SART1	Sart1			10602	-0.265	-0.3543	Yes
69	AQR	Aqr			10660	-0.272	-0.3501	Yes
70	NCBP1	Ncbp1			10759	-0.283	-0.3482	Yes
71	DDX42	Ddx42			10838	-0.290	-0.3449	Yes
72	HNRNPK	Hnrnpk			10856	-0.291	-0.3375	Yes
73	SNRNP40	Snrnp40			10857	-0.291	-0.3291	Yes
74	PPIE	Ppie			10912	-0.296	-0.3240	Yes
75	SNRPA	Snrpa			10956	-0.302	-0.3180	Yes
76	SNRPB2	Snrpb2			11011	-0.308	-0.3125	Yes
77	NCBP2	Ncbp2			11078	-0.317	-0.3076	Yes
78	SNW1	Snw1			11124	-0.322	-0.3012	Yes
79	THOC3	Thoc3			11244	-0.335	-0.2992	Yes
80	PPIH	Gm7879			11424	-0.356	-0.3004	Yes
81	SNRNP70	Snrnp70			11521	-0.367	-0.2960	Yes
82	SNRPD2	Snrpd2			11549	-0.370	-0.2870	Yes
83	CTNNBL1	Ctnnbl1			11572	-0.373	-0.2776	Yes
84	EIF4A3	Eif4a3			11584	-0.374	-0.2675	Yes
85	PRPF6	Prpf6			11669	-0.385	-0.2618	Yes
86	XAB2	Xab2			11722	-0.392	-0.2538	Yes
87	PRPF40B	Prpf40b			11858	-0.410	-0.2506	Yes
88	SRSF3	Srsf3			12136	-0.425	-0.2563	Yes
89	HNRNPA3	Gm17190			12147	-0.428	-0.2445	Yes
90	SRSF10	Srsf10			12168	-0.430	-0.2333	Yes
91	SNRPD1	Snrpd1			12202	-0.435	-0.2228	Yes
92	SF3A3	Sf3a3			12322	-0.445	-0.2176	Yes
93	LSM5	Lsm5			12482	-0.471	-0.2143	Yes
94	CDC5L	Cdc5l			12626	-0.492	-0.2093	Yes
95	DHX15	Dhx15			12630	-0.492	-0.1952	Yes
96	SF3B1	Sf3b1			12672	-0.499	-0.1833	Yes
97	HNRNPU	Hnrnpu			12930	-0.537	-0.1844	Yes
98	SRSF9	Srsf9			13001	-0.553	-0.1729	Yes
99	HNRNPM	Hnrnpm			13222	-0.602	-0.1697	Yes
100	ACIN1	Acin1			13254	-0.611	-0.1540	Yes
101	SRSF4	Srsf4			13332	-0.627	-0.1408	Yes
102	SNRPG	Snrpg			13379	-0.638	-0.1252	Yes
103	CDC40	Cdc40			13389	-0.640	-0.1072	Yes
104	THOC2	Thoc2			13592	-0.695	-0.1002	Yes
105	TCERG1	Tcerg1			13644	-0.710	-0.0829	Yes
106	LSM3	Lsm3			13697	-0.727	-0.0651	Yes
107	SRSF6	Srsf6			13709	-0.731	-0.0446	Yes
108	HNRNPA1	Hnrnpa1			13945	-0.801	-0.0366	Yes
109	TRA2A	Tra2a			14008	-0.823	-0.0167	Yes
110	SRSF7	Srsf7			14368	-0.957	-0.0122	Yes
111	SRSF5	Srsf5			14411	-0.976	0.0134	Yes
112	HSPA1L	Hspa1l			14418	-0.978	0.0414	Yes
113	SRSF2	Srsf2			14537	-1.046	0.0641	Yes

Fig 2: KEGG_SPLICEOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_SPLICEOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_SPLICEOSOME