Details for gene set KEGG_ACUTE_MYELOID_LEUKEMIA[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	NG
GeneSet	KEGG_ACUTE_MYELOID_LEUKEMIA
Enrichment Score (ES)	0.39030287
Normalized Enrichment Score (NES)	1.3764751
Nominal p-value	0.043902438
FDR q-value	0.27106103
FWER p-Value	0.987

Fig 1: Enrichment plot: KEGG_ACUTE_MYELOID_LEUKEMIA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LEF1	Lef1			46	4.174	0.0964	Yes
2	PIM1	Pim1			283	3.071	0.1543	Yes
3	RUNX1T1	Runx1t1			886	2.075	0.1648	Yes
4	FLT3	Flt3			1204	1.778	0.1866	Yes
5	IKBKG	Ikbkg			1361	1.649	0.2158	Yes
6	STAT3	Stat3			1395	1.620	0.2523	Yes
7	JUP	Jup			1509	1.546	0.2818	Yes
8	TCF7L1	Tcf7l1			2202	1.173	0.2650	Yes
9	NRAS	Nras			2446	1.065	0.2746	Yes
10	STAT5A	Stat5a			2464	1.056	0.2987	Yes
11	IKBKB	Ikbkb			2487	1.048	0.3222	Yes
12	SPI1	Spi1			2816	0.927	0.3231	Yes
13	ZBTB16	Zbtb16			2984	0.873	0.3331	Yes
14	BRAF	Braf			3403	0.752	0.3240	Yes
15	SOS2	Sos2			3744	0.664	0.3178	Yes
16	EIF4EBP1	Eif4ebp1			3763	0.660	0.3323	Yes
17	CEBPA	Cebpa			3801	0.652	0.3455	Yes
18	PIM2	Pim2			3850	0.636	0.3575	Yes
19	ARAF	Araf			3916	0.620	0.3681	Yes
20	MAPK3	Mapk3			4062	0.582	0.3726	Yes
21	CHUK	Chuk			4201	0.548	0.3767	Yes
22	KIT	Kit			4580	0.493	0.3640	Yes
23	STAT5B	Stat5b			4630	0.484	0.3724	Yes
24	PPARD	Ppard			4779	0.450	0.3735	Yes
25	CCNA1	Ccna1			4796	0.445	0.3831	Yes
26	PIK3CG	Pik3cg			4998	0.436	0.3805	Yes
27	RELA	Rela			5054	0.426	0.3871	Yes
28	PIK3CD	Pik3cd			5153	0.402	0.3903	Yes
29	PIK3R5	Pik3r5			6009	0.242	0.3408	No
30	BAD	Bad			6182	0.214	0.3348	No
31	RUNX1	Runx1			6217	0.206	0.3375	No
32	TCF7L2	Tcf7l2			6331	0.185	0.3346	No
33	HRAS	Hras			6623	0.128	0.3188	No
34	RARA	Rara			6698	0.116	0.3168	No
35	AKT2	Akt2			6809	0.094	0.3119	No
36	KRAS	Kras			6947	0.073	0.3048	No
37	PIK3CA	Pik3ca			7015	0.064	0.3020	No
38	AKT1	Akt1			7265	0.031	0.2867	No
39	SOS1	Sos1			7394	0.010	0.2786	No
40	MAP2K1	Map2k1			8218	-0.037	0.2263	No
41	MTOR	Mtor			8717	-0.129	0.1972	No
42	RPS6KB2	Rps6kb2			8775	-0.139	0.1968	No
43	PIK3CB	Pik3cb			9089	-0.193	0.1812	No
44	MAPK1	Mapk1			9564	-0.283	0.1573	No
45	TCF7	Tcf7			9904	-0.354	0.1438	No
46	GRB2	Grb2			10893	-0.492	0.0917	No
47	AKT3	Akt3			11086	-0.522	0.0917	No
48	RAF1	Raf1			11211	-0.549	0.0968	No
49	PIK3R1	Pik3r1			13040	-1.061	0.0039	No
50	MYC	Myc			13632	-1.357	-0.0019	No
51	NFKB1	Nfkb1			13962	-1.572	0.0142	No
52	PML	Pml			14047	-1.634	0.0477	No
53	CCND1	Ccnd1			14426	-2.005	0.0710	No

Fig 2: KEGG_ACUTE_MYELOID_LEUKEMIA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_ACUTE_MYELOID_LEUKEMIA: Random ES distribution   
Gene set null distribution of ES for KEGG_ACUTE_MYELOID_LEUKEMIA