Details for gene set KEGG_AXON_GUIDANCE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	NG
GeneSet	KEGG_AXON_GUIDANCE
Enrichment Score (ES)	0.37548095
Normalized Enrichment Score (NES)	1.515625
Nominal p-value	0.0025125628
FDR q-value	0.15544957
FWER p-Value	0.778

Fig 1: Enrichment plot: KEGG_AXON_GUIDANCE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SRGAP1	Srgap1			20	4.539	0.0300	Yes
2	PLXNC1	Plxnc1			50	4.120	0.0565	Yes
3	SEMA3E	Sema3e			100	3.793	0.0794	Yes
4	L1CAM	L1cam			132	3.633	0.1025	Yes
5	ABLIM3	Ablim3			161	3.512	0.1248	Yes
6	CXCR4	Cxcr4			164	3.494	0.1488	Yes
7	EPHA4	Epha4			180	3.456	0.1716	Yes
8	SEMA3C	Sema3c			264	3.133	0.1878	Yes
9	SEMA6C	Sema6c			300	3.028	0.2064	Yes
10	ROBO1	Robo1			425	2.745	0.2173	Yes
11	GNAI1	Gnai1			478	2.643	0.2321	Yes
12	ROBO2	Robo2			519	2.575	0.2473	Yes
13	EPHB4	Ephb4			627	2.394	0.2568	Yes
14	EPHB2	Ephb2			659	2.343	0.2709	Yes
15	NTN4	Ntn4			660	2.343	0.2871	Yes
16	EFNA3	Efna3			664	2.333	0.3030	Yes
17	ABLIM2	Ablim2			856	2.120	0.3052	Yes
18	NCK2	Nck2			1174	1.794	0.2969	Yes
19	DPYSL5	Dpysl5			1228	1.762	0.3056	Yes
20	SEMA4D	Sema4d			1270	1.728	0.3149	Yes
21	EPHA7	Epha7			1304	1.702	0.3245	Yes
22	RHOD	Rhod			1310	1.699	0.3359	Yes
23	EFNB3	Efnb3			1410	1.609	0.3405	Yes
24	NFAT5	Nfat5			1510	1.545	0.3447	Yes
25	SEMA3B	Sema3b			1525	1.534	0.3544	Yes
26	PLXNA2	Plxna2			1599	1.484	0.3599	Yes
27	SEMA3D	Sema3d			1651	1.454	0.3666	Yes
28	DPYSL2	Dpysl2			1892	1.321	0.3601	Yes
29	EFNA4	Efna4			1916	1.308	0.3676	Yes
30	PLXNB1	Plxnb1			2164	1.189	0.3598	Yes
31	SEMA6A	Sema6a			2212	1.169	0.3648	Yes
32	NRAS	Nras			2446	1.065	0.3570	Yes
33	CHP1	Chp1			2485	1.048	0.3617	Yes
34	GSK3B	Gsk3b			2498	1.045	0.3682	Yes
35	CDK5	Cdk5			2518	1.035	0.3741	Yes
36	CXCL12	Cxcl12			2617	1.002	0.3746	Yes
37	PLXNA1	Plxna1			2795	0.932	0.3695	Yes
38	ROBO3	Robo3			2803	0.931	0.3755	Yes
39	UNC5A	Unc5a			3084	0.849	0.3631	No
40	SEMA6D	Sema6d			3152	0.827	0.3645	No
41	SLIT1	Slit1			3297	0.785	0.3606	No
42	ARHGEF12	Arhgef12			3912	0.621	0.3250	No
43	FYN	Fyn			3963	0.606	0.3259	No
44	PLXNB2	Plxnb2			4011	0.594	0.3269	No
45	MAPK3	Mapk3			4062	0.582	0.3277	No
46	CFL2	Cfl2			4299	0.531	0.3160	No
47	PLXNB3	Plxnb3			4383	0.516	0.3142	No
48	LRRC4C	Lrrc4c			4409	0.507	0.3161	No
49	SLIT2	Slit2			4532	0.498	0.3116	No
50	NFATC1	Nfatc1			4612	0.487	0.3098	No
51	SEMA5B	Sema5b			4926	0.438	0.2925	No
52	ROCK1	Rock1			5029	0.430	0.2888	No
53	FES	Fes			5357	0.362	0.2701	No
54	PLXNA3	Plxna3			5370	0.359	0.2718	No
55	ABLIM1	Ablim1			5485	0.340	0.2667	No
56	RAC3	Rac3			5603	0.316	0.2613	No
57	SEMA4F	Sema4f			5826	0.279	0.2488	No
58	EPHB1	Ephb1			5917	0.259	0.2448	No
59	LIMK1	Limk1			5964	0.250	0.2435	No
60	EFNA2	Efna2			6241	0.202	0.2270	No
61	PAK3	Pak3			6312	0.188	0.2237	No
62	RHOA	Rhoa			6593	0.134	0.2065	No
63	HRAS	Hras			6623	0.128	0.2054	No
64	PPP3CA	Ppp3ca			6911	0.077	0.1873	No
65	KRAS	Kras			6947	0.073	0.1856	No
66	LIMK2	Limk2			6958	0.072	0.1854	No
67	NFATC3	Nfatc3			7177	0.044	0.1716	No
68	EFNB1	Efnb1			7315	0.024	0.1628	No
69	SEMA3F	Sema3f			7439	0.004	0.1549	No
70	PPP3R2	Ppp3r2			7742	0.000	0.1353	No
71	UNC5D	Unc5d			7764	0.000	0.1339	No
72	PAK5	Pak7			7865	0.000	0.1274	No
73	EPHA2	Epha2			8191	-0.031	0.1065	No
74	SEMA4B	Sema4b			8280	-0.048	0.1011	No
75	EPHA8	Epha8			8560	-0.100	0.0837	No
76	SRGAP3	Srgap3			8595	-0.106	0.0822	No
77	NCK1	Nck1			8654	-0.117	0.0793	No
78	ITGB1	Itgb1			8679	-0.122	0.0785	No
79	PAK6	Pak6			8897	-0.161	0.0656	No
80	EFNA1	Efna1			9027	-0.182	0.0584	No
81	NFATC4	Nfatc4			9073	-0.190	0.0568	No
82	EFNA5	Efna5			9255	-0.222	0.0466	No
83	PPP3CB	Ppp3cb			9276	-0.225	0.0468	No
84	CDC42	Cdc42			9285	-0.228	0.0479	No
85	ROCK2	Rock2			9367	-0.243	0.0443	No
86	SEMA4C	Sema4c			9517	-0.274	0.0365	No
87	MAPK1	Mapk1			9564	-0.283	0.0355	No
88	PAK2	Pak2			9585	-0.288	0.0362	No
89	ABL1	Abl1			9747	-0.322	0.0279	No
90	GNAI2	Gnai2			9851	-0.342	0.0236	No
91	CFL1	Cfl1			10168	-0.407	0.0059	No
92	EPHA6	Epha6			10270	-0.418	0.0022	No
93	PAK4	Pak4			10670	-0.450	-0.0206	No
94	NTNG1	Ntng1			10863	-0.489	-0.0297	No
95	EPHB6	Ephb6			10901	-0.494	-0.0287	No
96	GNAI3	Gnai3			10923	-0.498	-0.0266	No
97	CHP2	Chp2			10936	-0.499	-0.0240	No
98	UNC5B	Unc5b			10999	-0.510	-0.0245	No
99	EPHB3	Ephb3			11070	-0.520	-0.0254	No
100	RAC2	Rac2			11097	-0.524	-0.0235	No
101	DCC	Dcc			11123	-0.530	-0.0215	No
102	RAC1	Rac1			11474	-0.610	-0.0400	No
103	PTK2	Ptk2			11499	-0.614	-0.0373	No
104	SEMA4A	Sema4a			11767	-0.692	-0.0499	No
105	SEMA6B	Sema6b			12778	-0.967	-0.1088	No
106	SEMA4G	Sema4g			12923	-1.019	-0.1112	No
107	RASA1	Rasa1			12924	-1.019	-0.1042	No
108	SEMA3G	Sema3g			13021	-1.052	-0.1031	No
109	NTN1	Ntn1			13123	-1.101	-0.1021	No
110	RND1	Rnd1			13172	-1.118	-0.0975	No
111	MET	Met			13331	-1.194	-0.0996	No
112	PAK1	Pak1			13387	-1.226	-0.0947	No
113	RGS3	Rgs3			13396	-1.230	-0.0867	No
114	PPP3CC	Ppp3cc			13689	-1.388	-0.0961	No
115	SLIT3	Slit3			13762	-1.432	-0.0909	No
116	EFNB2	Efnb2			13947	-1.562	-0.0921	No
117	NTN3	Ntn3			14176	-1.738	-0.0949	No
118	UNC5C	Unc5c			14190	-1.749	-0.0837	No
119	SEMA5A	Sema5a			14444	-2.036	-0.0861	No
120	NGEF	Ngef			14579	-2.223	-0.0795	No
121	NRP1	Nrp1			14655	-2.337	-0.0683	No
122	EPHA5	Epha5			14782	-2.534	-0.0590	No
123	EPHA3	Epha3			14914	-2.792	-0.0483	No
124	SEMA7A	Sema7a			14948	-2.872	-0.0306	No
125	SEMA3A	Sema3a			14987	-2.961	-0.0127	No
126	NFATC2	Nfatc2			15117	-3.265	0.0014	No
127	EPHA1	Epha1			15238	-3.629	0.0186	No

Fig 2: KEGG_AXON_GUIDANCE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_AXON_GUIDANCE: Random ES distribution   
Gene set null distribution of ES for KEGG_AXON_GUIDANCE