Details for gene set KEGG_CELL_CYCLE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_CELL_CYCLE
Enrichment Score (ES)	-0.6438858
Normalized Enrichment Score (NES)	-2.4225614
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_CELL_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GADD45A	Gadd45a			356	2.893	-0.0056	No
2	SFN	Sfn			804	2.179	-0.0214	No
3	RB1	Rb1			2061	1.239	-0.0953	No
4	MDM2	Mdm2			2120	1.210	-0.0918	No
5	SMAD2	Smad2			2126	1.206	-0.0848	No
6	GSK3B	Gsk3b			2498	1.045	-0.1025	No
7	WEE1	Wee1			2932	0.886	-0.1252	No
8	EP300	Ep300			3456	0.737	-0.1547	No
9	CREBBP	Crebbp			3739	0.665	-0.1690	No
10	SMC1B	Smc1b			3789	0.654	-0.1682	No
11	YWHAG	Ywhag			3886	0.628	-0.1706	No
12	SMAD3	Smad3			4087	0.576	-0.1801	No
13	PRKDC	Prkdc			4138	0.562	-0.1799	No
14	CCNA1	Ccna1			4796	0.445	-0.2199	No
15	CDC14A	Cdc14a			5008	0.434	-0.2309	No
16	STAG2	Stag2			5124	0.409	-0.2359	No
17	ZBTB17	Zbtb17			5702	0.299	-0.2716	No
18	CDKN1A	Cdkn1a			5982	0.248	-0.2882	No
19	ANAPC2	Anapc2			6036	0.237	-0.2902	No
20	CDK4	Cdk4			6067	0.233	-0.2907	No
21	SMAD4	Smad4			6167	0.216	-0.2958	No
22	TGFB2	Tgfb2			6387	0.174	-0.3090	No
23	CCND3	Ccnd3			6410	0.169	-0.3094	No
24	YWHAB	Ywhab			6436	0.165	-0.3100	No
25	RBL2	Rbl2			6445	0.163	-0.3095	No
26	ATM	Atm			6537	0.144	-0.3146	No
27	GADD45B	Gadd45b			7375	0.013	-0.3688	No
28	RBX1	Rbx1			7389	0.011	-0.3696	No
29	CDK6	Cdk6			7454	0.001	-0.3737	No
30	WEE2	Wee2			7571	0.000	-0.3812	No
31	MAD2L2	Mad2l2			8054	-0.005	-0.4125	No
32	TGFB1	Tgfb1			8795	-0.144	-0.4596	No
33	CDKN1B	Cdkn1b			8825	-0.147	-0.4606	No
34	CCNB3	Ccnb3			8893	-0.160	-0.4640	No
35	ORC4	Orc4			8947	-0.169	-0.4664	No
36	CDC27	Cdc27			8952	-0.170	-0.4657	No
37	ANAPC10	Anapc10			8964	-0.171	-0.4653	No
38	PCNA	Pcna			9052	-0.186	-0.4699	No
39	CDK2	Cdk2			9072	-0.189	-0.4699	No
40	CCNH	Ccnh			9178	-0.208	-0.4755	No
41	YWHAH	Ywhah			9181	-0.208	-0.4744	No
42	SKP1	Skp1a			9322	-0.234	-0.4820	No
43	ANAPC1	Anapc1			9469	-0.264	-0.4899	No
44	ABL1	Abl1			9747	-0.322	-0.5059	No
45	YWHAQ	Ywhaq			9796	-0.330	-0.5070	No
46	E2F1	E2f1			10020	-0.376	-0.5192	No
47	ANAPC13	Anapc13			10027	-0.377	-0.5173	No
48	ANAPC4	Anapc4			10123	-0.395	-0.5211	No
49	YWHAZ	Ywhaz			10438	-0.425	-0.5389	No
50	GADD45G	Gadd45g			10766	-0.471	-0.5573	No
51	CDC16	Cdc16			10775	-0.472	-0.5549	No
52	E2F3	E2f3			11074	-0.521	-0.5711	No
53	ANAPC5	Anapc5			11229	-0.553	-0.5778	No
54	ORC3	Orc3			11363	-0.581	-0.5829	No
55	CUL1	Cul1			11415	-0.595	-0.5826	No
56	CDK7	Cdk7			11668	-0.661	-0.5949	No
57	ANAPC7	Anapc7			11828	-0.707	-0.6009	No
58	TP53	Trp53			11831	-0.708	-0.5968	No
59	CDC25B	Cdc25b			11869	-0.718	-0.5948	No
60	E2F5	E2f5			11877	-0.721	-0.5909	No
61	TGFB3	Tgfb3			11962	-0.747	-0.5918	No
62	BUB3	Bub3			12066	-0.775	-0.5938	No
63	CDC26	Cdc26			12210	-0.811	-0.5982	No
64	YWHAE	Ywhae			12226	-0.815	-0.5942	No
65	ATR	Atr			12470	-0.873	-0.6047	No
66	STAG1	Stag1			12512	-0.883	-0.6020	No
67	CDC25A	Cdc25a			12552	-0.893	-0.5991	No
68	MAD1L1	Mad1l1			12575	-0.901	-0.5951	No
69	FZR1	Fzr1			12858	-0.991	-0.6074	No
70	CHEK2	Chek2			13060	-1.073	-0.6139	No
71	HDAC2	Hdac2			13243	-1.156	-0.6187	No
72	MYC	Myc			13632	-1.357	-0.6357	Yes
73	HDAC1	Hdac1			13740	-1.420	-0.6340	Yes
74	E2F4	E2f4			13753	-1.426	-0.6261	Yes
75	SMC1A	Smc1a			13851	-1.489	-0.6234	Yes
76	CDC23	Cdc23			13853	-1.489	-0.6144	Yes
77	SMC3	Smc3			13909	-1.529	-0.6087	Yes
78	TFDP2	Tfdp2			13937	-1.555	-0.6010	Yes
79	MCM2	Mcm2			14070	-1.650	-0.5996	Yes
80	DBF4	Dbf4			14177	-1.738	-0.5960	Yes
81	E2F2	E2f2			14180	-1.744	-0.5855	Yes
82	TFDP1	Tfdp1			14207	-1.769	-0.5765	Yes
83	RAD21	Rad21			14312	-1.865	-0.5719	Yes
84	PKMYT1	Pkmyt1			14372	-1.926	-0.5641	Yes
85	CDC7	Cdc7			14391	-1.951	-0.5534	Yes
86	CCND1	Ccnd1			14426	-2.005	-0.5435	Yes
87	ORC1	Orc1			14431	-2.009	-0.5315	Yes
88	MCM4	Mcm4			14442	-2.032	-0.5199	Yes
89	ORC5	Orc5			14446	-2.039	-0.5077	Yes
90	CDKN1C	Cdkn1c			14460	-2.055	-0.4961	Yes
91	ORC2	Orc2			14487	-2.085	-0.4851	Yes
92	ORC6	Orc6			14539	-2.157	-0.4754	Yes
93	MCM7	Mcm7			14645	-2.323	-0.4681	Yes
94	SKP2	Skp2			14837	-2.642	-0.4645	Yes
95	CDKN2D	Cdkn2d			14918	-2.807	-0.4526	Yes
96	MCM3	Mcm3			14982	-2.950	-0.4388	Yes
97	RBL1	Rbl1			15021	-3.024	-0.4230	Yes
98	CDKN2C	Cdkn2c			15043	-3.083	-0.4056	Yes
99	MCM6	Mcm6			15061	-3.125	-0.3878	Yes
100	CCNE1	Ccne1			15142	-3.344	-0.3727	Yes
101	CHEK1	Chek1			15169	-3.426	-0.3536	Yes
102	CDK1	Cdk1			15207	-3.532	-0.3346	Yes
103	MAD2L1	Mad2l1			15224	-3.587	-0.3139	Yes
104	CCNE2	Ccne2			15245	-3.650	-0.2931	Yes
105	CDC45	Cdc45			15263	-3.711	-0.2717	Yes
106	MCM5	Mcm5			15314	-3.849	-0.2516	Yes
107	CDC6	Cdc6			15404	-4.168	-0.2321	Yes
108	CCNB1	Ccnb1			15417	-4.218	-0.2073	Yes
109	CDC25C	Cdc25c			15428	-4.264	-0.1821	Yes
110	ESPL1	Espl1			15438	-4.313	-0.1565	Yes
111	CDC20	Cdc20			15447	-4.345	-0.1307	Yes
112	BUB1	Bub1			15466	-4.393	-0.1052	Yes
113	CCNB2	Ccnb2			15478	-4.435	-0.0790	Yes
114	TTK	Ttk			15484	-4.462	-0.0523	Yes
115	CCNA2	Ccna2			15489	-4.484	-0.0254	Yes
116	PLK1	Plk1			15502	-4.560	0.0015	Yes

Fig 2: KEGG_CELL_CYCLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_CELL_CYCLE: Random ES distribution   
Gene set null distribution of ES for KEGG_CELL_CYCLE