Details for gene set KEGG_FOCAL

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_FOCAL_ADHESION
Enrichment Score (ES)	-0.34347287
Normalized Enrichment Score (NES)	-1.3968558
Nominal p-value	0.0094191525
FDR q-value	0.21992494
FWER p-Value	0.991

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	VWF	Vwf	3	4.877	0.0227	No
2	KDR	Kdr	5	4.757	0.0451	No
3	COL4A4	Col4a4	86	3.885	0.0581	No
4	FLT4	Flt4	131	3.633	0.0723	No
5	COL11A2	Col11a2	138	3.605	0.0889	No
6	LAMB3	Lamb3	239	3.202	0.0974	No
7	LAMA1	Lama1	268	3.121	0.1103	No
8	CHAD	Chad	308	3.010	0.1219	No
9	PARVG	Parvg	406	2.785	0.1287	No
10	THBS3	Thbs3	732	2.258	0.1181	No
11	ITGB5	Itgb5	901	2.055	0.1168	No
12	PDGFB	Pdgfb	928	2.013	0.1246	No
13	LAMA3	Lama3	1044	1.897	0.1260	No
14	ITGA9	Itga9	1116	1.845	0.1301	No
15	RELN	Reln	1358	1.655	0.1222	No
16	ITGB7	Itgb7	1455	1.573	0.1233	No
17	VEGFB	Vegfb	1589	1.494	0.1217	No
18	ITGB8	Itgb8	1662	1.445	0.1238	No
19	VEGFC	Vegfc	1684	1.429	0.1291	No
20	ELK1	Elk1	1731	1.412	0.1328	No
21	LAMB2	Lamb2	1853	1.339	0.1312	No
22	MYL12B	Myl12b	1918	1.307	0.1331	No
23	VEGFA	Vegfa	1972	1.282	0.1357	No
24	TNXB	Tnxb	2124	1.208	0.1315	No
25	SHC1	Shc1	2179	1.183	0.1336	No
26	CTNNB1	Ctnnb1	2284	1.137	0.1322	No
27	FN1	Fn1	2488	1.047	0.1238	No
28	GSK3B	Gsk3b	2498	1.045	0.1282	No
29	ITGB6	Itgb6	2720	0.961	0.1183	No
30	LAMA5	Lama5	3012	0.866	0.1034	No
31	COL5A2	Col5a2	3272	0.793	0.0902	No
32	ITGA10	Gm42957	3275	0.792	0.0938	No
33	PRKCG	Prkcg	3309	0.781	0.0953	No
34	BRAF	Braf	3403	0.752	0.0928	No
35	ERBB2	Erbb2	3405	0.752	0.0963	No
36	DIAPH1	Diaph1	3692	0.678	0.0808	No
37	SOS2	Sos2	3744	0.664	0.0806	No
38	MAPK10	Mapk10	3880	0.629	0.0748	No
39	FYN	Fyn	3963	0.606	0.0723	No
40	COL2A1	Col2a1	3976	0.604	0.0743	No
41	PARVB	Parvb	3980	0.603	0.0770	No
42	MAPK3	Mapk3	4062	0.582	0.0744	No
43	FLNA	Flna	4233	0.542	0.0659	No
44	ARHGAP35	Arhgap35	4296	0.532	0.0644	No
45	IGF1R	Igf1r	4597	0.491	0.0471	No
46	PTEN	Pten	4601	0.490	0.0492	No
47	MYLK3	Mylk3	4890	0.441	0.0325	No
48	PIK3CG	Pik3cg	4998	0.436	0.0276	No
49	ROCK1	Rock1	5029	0.430	0.0276	No
50	PIK3CD	Pik3cd	5153	0.402	0.0215	No
51	ITGA11	Itga11	5429	0.351	0.0052	No
52	PDPK1	Pdpk1	5510	0.337	0.0016	No
53	CRK	Crk	5578	0.323	-0.0013	No
54	RAC3	Rac3	5603	0.316	-0.0013	No
55	MAPK8	Mapk8	5645	0.310	-0.0026	No
56	ACTN2	Actn2	5714	0.296	-0.0056	No
57	ITGA7	Itga7	5851	0.275	-0.0132	No
58	THBS4	Thbs4	5854	0.275	-0.0120	No
59	CAPN2	Capn2	6003	0.243	-0.0205	No
60	PIK3R5	Pik3r5	6009	0.242	-0.0197	No
61	BAD	Bad	6182	0.214	-0.0299	No
62	PAK3	Pak3	6312	0.188	-0.0374	No
63	PDGFD	Pdgfd	6366	0.178	-0.0401	No
64	PXN	Pxn	6405	0.170	-0.0417	No
65	CCND3	Ccnd3	6410	0.169	-0.0412	No
66	PIP5K1C	Pip5k1c	6519	0.148	-0.0476	No
67	RAP1B	Rap1b	6570	0.138	-0.0502	No
68	RHOA	Rhoa	6593	0.134	-0.0510	No
69	HRAS	Hras	6623	0.128	-0.0523	No
70	BCAR1	Bcar1	6688	0.118	-0.0559	No
71	VAV2	Vav2	6769	0.101	-0.0606	No
72	AKT2	Akt2	6809	0.094	-0.0627	No
73	PDGFA	Pdgfa	6878	0.084	-0.0668	No
74	ITGA3	Itga3	6954	0.072	-0.0713	No
75	CAV3	Cav3	6975	0.070	-0.0723	No
76	MYL10	Myl10	7002	0.065	-0.0737	No
77	PIK3CA	Pik3ca	7015	0.064	-0.0742	No
78	AKT1	Akt1	7265	0.031	-0.0903	No
79	FLNB	Flnb	7268	0.030	-0.0902	No
80	SOS1	Sos1	7394	0.010	-0.0983	No
81	VAV1	Vav1	7567	0.000	-0.1096	No
82	IBSP	Ibsp	7671	0.000	-0.1163	No
83	VTN	Vtn	7813	0.000	-0.1255	No
84	PAK5	Pak7	7865	0.000	-0.1288	No
85	COMP	Comp	8174	-0.027	-0.1488	No
86	MAP2K1	Map2k1	8218	-0.037	-0.1514	No
87	LAMC3	Lamc3	8307	-0.054	-0.1569	No
88	FLT1	Flt1	8504	-0.090	-0.1692	No
89	XIAP	Xiap	8586	-0.105	-0.1740	No
90	RAPGEF1	Rapgef1	8597	-0.107	-0.1742	No
91	ITGAV	Itgav	8611	-0.109	-0.1745	No
92	ITGB1	Itgb1	8679	-0.122	-0.1783	No
93	LAMA2	Lama2	8683	-0.123	-0.1779	No
94	FLNC	Flnc	8813	-0.146	-0.1856	No
95	PAK6	Pak6	8897	-0.161	-0.1903	No
96	PIK3CB	Pik3cb	9089	-0.193	-0.2019	No
97	SRC	Src	9120	-0.199	-0.2029	No
98	PPP1R12A	Ppp1r12a	9267	-0.224	-0.2113	No
99	CDC42	Cdc42	9285	-0.228	-0.2114	No
100	CRKL	Crkl	9288	-0.229	-0.2104	No
101	ITGA5	Itga5	9293	-0.230	-0.2096	No
102	ROCK2	Rock2	9367	-0.243	-0.2132	No
103	PPP1CB	Ppp1cb	9385	-0.246	-0.2132	No
104	LAMB1	Lamb1	9484	-0.268	-0.2183	No
105	MAPK1	Mapk1	9564	-0.283	-0.2221	No
106	PAK2	Pak2	9585	-0.288	-0.2221	No
107	MYLK2	Mylk2	9680	-0.307	-0.2268	No
108	BCL2	Bcl2	9797	-0.330	-0.2328	No
109	COL5A3	Col5a3	9838	-0.340	-0.2338	No
110	MAPK9	Mapk9	9981	-0.369	-0.2413	No
111	VASP	Vasp	10030	-0.377	-0.2427	No
112	ITGA2B	Itga2b	10043	-0.379	-0.2417	No
113	TLN1	Tln1	10115	-0.393	-0.2445	No
114	ACTN1	Actn1	10481	-0.433	-0.2662	No
115	MYLPF	Mylpf	10499	-0.436	-0.2653	No
116	MYL2	Myl2	10581	-0.440	-0.2685	No
117	PAK4	Pak4	10670	-0.450	-0.2721	No
118	PDGFC	Pdgfc	10694	-0.456	-0.2715	No
119	BIRC2	Birc2	10763	-0.470	-0.2737	No
120	LAMC2	Lamc2	10767	-0.471	-0.2717	No
121	GRB2	Grb2	10893	-0.492	-0.2775	No
122	AKT3	Akt3	11086	-0.522	-0.2876	No
123	RAC2	Rac2	11097	-0.524	-0.2858	No
124	MYL7	Myl7	11186	-0.543	-0.2889	No
125	VAV3	Vav3	11188	-0.543	-0.2864	No
126	RAF1	Raf1	11211	-0.549	-0.2853	No
127	MYL12A	Myl12a	11303	-0.569	-0.2886	No
128	ARHGAP5	Arhgap5	11461	-0.606	-0.2959	No
129	RAC1	Rac1	11474	-0.610	-0.2939	No
130	PTK2	Ptk2	11499	-0.614	-0.2925	No
131	PPP1CA	Ppp1ca	11678	-0.663	-0.3010	No
132	RAP1A	Rap1a	11705	-0.672	-0.2995	No
133	TLN2	Tln2	11731	-0.681	-0.2980	No
134	LAMC1	Lamc1	11810	-0.703	-0.2998	No
135	DOCK1	Dock1	11875	-0.720	-0.3005	No
136	ITGA8	Itga8	11931	-0.738	-0.3007	No
137	COL6A6	Col6a6	12133	-0.793	-0.3100	No
138	ITGA4	Itga4	12644	-0.922	-0.3390	Yes
139	BIRC3	Birc3	12693	-0.938	-0.3377	Yes
140	VCL	Vcl	12783	-0.967	-0.3389	Yes
141	COL4A2	Col4a2	12787	-0.968	-0.3346	Yes
142	COL1A2	Col1a2	12855	-0.990	-0.3343	Yes
143	PPP1CC	Ppp1cc	12863	-0.993	-0.3301	Yes
144	THBS1	Thbs1	12909	-1.012	-0.3282	Yes
145	COL4A1	Col4a1	12976	-1.034	-0.3277	Yes
146	PIK3R1	Pik3r1	13040	-1.061	-0.3268	Yes
147	ACTB	Actb	13151	-1.112	-0.3287	Yes
148	CAV2	Cav2	13229	-1.147	-0.3284	Yes
149	EGF	Egf	13295	-1.179	-0.3271	Yes
150	MYL9	Myl9	13308	-1.184	-0.3223	Yes
151	COL4A6	Col4a6	13326	-1.191	-0.3178	Yes
152	ITGB4	Itgb4	13329	-1.194	-0.3123	Yes
153	MET	Met	13331	-1.194	-0.3067	Yes
154	ACTG1	Actg1	13360	-1.209	-0.3029	Yes
155	PAK1	Pak1	13387	-1.226	-0.2988	Yes
156	PRKCA	Prkca	13464	-1.260	-0.2978	Yes
157	ACTN4	Actn4	13496	-1.278	-0.2938	Yes
158	PGF	Pgf	13750	-1.425	-0.3036	Yes
159	ITGA6	Itga6	13878	-1.505	-0.3048	Yes
160	PARVA	Parva	13973	-1.578	-0.3035	Yes
161	COL11A1	Col11a1	14005	-1.603	-0.2980	Yes
162	ITGA2	Itga2	14025	-1.616	-0.2917	Yes
163	ITGA1	Itga1	14129	-1.695	-0.2904	Yes
164	PDGFRB	Pdgfrb	14200	-1.757	-0.2867	Yes
165	EGFR	Egfr	14212	-1.772	-0.2791	Yes
166	SHC4	Shc4	14252	-1.803	-0.2731	Yes
167	VEGFD	Vegfd	14322	-1.872	-0.2688	Yes
168	ZYX	Zyx	14368	-1.920	-0.2627	Yes
169	COL5A1	Col5a1	14386	-1.943	-0.2547	Yes
170	CCND1	Ccnd1	14426	-2.005	-0.2478	Yes
171	LAMA4	Lama4	14633	-2.302	-0.2504	Yes
172	MYLK	Mylk	14640	-2.317	-0.2399	Yes
173	JUN	Jun	14653	-2.336	-0.2297	Yes
174	COL6A3	Col6a3	14666	-2.360	-0.2194	Yes
175	ILK	Ilk	14692	-2.387	-0.2098	Yes
176	SHC3	Shc3	14744	-2.492	-0.2014	Yes
177	PDGFRA	Pdgfra	14799	-2.561	-0.1929	Yes
178	COL1A1	Col1a1	14821	-2.614	-0.1819	Yes
179	TNR	Tnr	14834	-2.636	-0.1703	Yes
180	CAV1	Cav1	14857	-2.675	-0.1592	Yes
181	ACTN3	Actn3	14899	-2.753	-0.1489	Yes
182	COL6A1	Col6a1	14920	-2.813	-0.1370	Yes
183	SPP1	Spp1	15038	-3.069	-0.1302	Yes
184	IGF1	Igf1	15103	-3.222	-0.1192	Yes
185	COL6A2	Col6a2	15107	-3.232	-0.1042	Yes
186	RASGRF1	Rasgrf1	15150	-3.350	-0.0911	Yes
187	HGF	Hgf	15289	-3.790	-0.0823	Yes
188	COL3A1	Col3a1	15340	-3.917	-0.0671	Yes
189	THBS2	Thbs2	15342	-3.926	-0.0487	Yes
190	TNN	Tnn	15364	-4.000	-0.0313	Yes
191	TNC	Tnc	15443	-4.338	-0.0160	Yes
192	PRKCB	Prkcb	15495	-4.518	0.0020	Yes