Details for gene set KEGG_LYSOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	NG
GeneSet	KEGG_LYSOSOME
Enrichment Score (ES)	0.5862246
Normalized Enrichment Score (NES)	2.3299654
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_LYSOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NEU1	Neu1			115	3.729	0.0197	Yes
2	MCOLN1	Mcoln1			195	3.401	0.0393	Yes
3	GLA	Gla			214	3.309	0.0622	Yes
4	GBA	Gba			316	2.987	0.0774	Yes
5	CTNS	Ctns			318	2.982	0.0990	Yes
6	ATP6V0B	Atp6v0b			326	2.960	0.1201	Yes
7	LAMP1	Lamp1			346	2.915	0.1401	Yes
8	GNPTG	Gnptg			368	2.858	0.1595	Yes
9	CTSA	Ctsa			391	2.811	0.1786	Yes
10	TPP1	Tpp1			437	2.717	0.1954	Yes
11	SLC17A5	Slc17a5			446	2.699	0.2145	Yes
12	ATP6V0D1	Atp6v0d1			505	2.590	0.2296	Yes
13	NPC1	Npc1			518	2.575	0.2476	Yes
14	MANBA	Manba			575	2.473	0.2620	Yes
15	HEXB	Hexb			630	2.389	0.2758	Yes
16	MAN2B1	Man2b1			753	2.240	0.2842	Yes
17	ATP6AP1	Atp6ap1			777	2.216	0.2989	Yes
18	GNS	Gns			789	2.195	0.3141	Yes
19	LAMP2	Lamp2			827	2.152	0.3274	Yes
20	SORT1	Sort1			888	2.074	0.3386	Yes
21	GGA2	Gga2			935	2.007	0.3502	Yes
22	HYAL1	Hyal1			959	1.983	0.3631	Yes
23	ASAH1	Asah1			967	1.977	0.3771	Yes
24	ATP6V0C	Atp6v0c			1074	1.875	0.3838	Yes
25	NAGPA	Nagpa			1078	1.873	0.3973	Yes
26	GAA	Gaa			1086	1.865	0.4104	Yes
27	ARSA	Arsa			1129	1.833	0.4210	Yes
28	SUMF1	Sumf1			1175	1.794	0.4311	Yes
29	ACP5	Acp5			1176	1.792	0.4442	Yes
30	AP3D1	Ap3d1			1211	1.773	0.4549	Yes
31	ATP6V1H	Atp6v1h			1338	1.675	0.4589	Yes
32	TCIRG1	Tcirg1			1341	1.672	0.4709	Yes
33	LIPA	Lipa			1372	1.642	0.4809	Yes
34	SCARB2	Scarb2			1396	1.620	0.4912	Yes
35	NPC2	Npc2			1423	1.600	0.5012	Yes
36	PSAP	Psap			1529	1.533	0.5055	Yes
37	DNASE2	Dnase2a			1553	1.517	0.5151	Yes
38	CTSW	Ctsw			1561	1.514	0.5257	Yes
39	IGF2R	Igf2r			1564	1.512	0.5365	Yes
40	CLTC	Cltc			1572	1.504	0.5470	Yes
41	GALC	Galc			1630	1.468	0.5540	Yes
42	CTSK	Ctsk			1699	1.423	0.5599	Yes
43	IDUA	Idua			1744	1.404	0.5673	Yes
44	PPT1	Ppt1			1959	1.286	0.5628	Yes
45	LAPTM4B	Laptm4b			2024	1.253	0.5677	Yes
46	CD63	Cd63			2068	1.235	0.5739	Yes
47	LAPTM4A	Laptm4a			2160	1.190	0.5767	Yes
48	SGSH	Sgsh			2229	1.158	0.5807	Yes
49	NAGA	Naga			2502	1.042	0.5707	Yes
50	ATP6V0A1	Atp6v0a1			2713	0.963	0.5640	Yes
51	CTSB	Ctsb			2767	0.943	0.5675	Yes
52	ARSG	Arsg			2792	0.934	0.5727	Yes
53	GGA3	Gga3			2831	0.922	0.5769	Yes
54	AP3B1	Ap3b1			2877	0.905	0.5806	Yes
55	AGA	Aga			2917	0.891	0.5846	Yes
56	CD164	Cd164			3002	0.869	0.5854	Yes
57	FUCA1	Fuca1			3185	0.819	0.5796	Yes
58	ABCA2	Abca2			3258	0.796	0.5807	Yes
59	SMPD1	Smpd1			3313	0.780	0.5829	Yes
60	MFSD8	Mfsd8			3422	0.746	0.5813	Yes
61	GGA1	Gga1			3549	0.713	0.5783	Yes
62	GM2A	Gm2a			3569	0.708	0.5823	Yes
63	AP4E1	Ap4e1			3696	0.677	0.5790	Yes
64	GLB1	Glb1			3735	0.665	0.5814	Yes
65	CLTA	Clta			3736	0.665	0.5862	Yes
66	GNPTAB	Gnptab			3930	0.614	0.5782	No
67	ACP2	Acp2			4027	0.590	0.5762	No
68	AP3S1	Ap3s1			4098	0.573	0.5759	No
69	HGSNAT	Hgsnat			4394	0.514	0.5605	No
70	GUSB	Gusb			4596	0.491	0.5510	No
71	LGMN	Lgmn			4631	0.483	0.5523	No
72	AP1S2	Ap1s2			5011	0.434	0.5309	No
73	AP1M1	Ap1m1			5481	0.341	0.5029	No
74	M6PR	M6pr			5721	0.296	0.4896	No
75	SLC11A2	Slc11a2			5745	0.291	0.4902	No
76	ATP6V0A2	Atp6v0a2			5843	0.277	0.4859	No
77	AP3M2	Ap3m2			5937	0.256	0.4818	No
78	PLA2G15	Pla2g15			5950	0.253	0.4828	No
79	CTSO	Ctso			6136	0.221	0.4724	No
80	NAGLU	Naglu			6408	0.169	0.4561	No
81	AP1G1	Ap1g1			6452	0.162	0.4545	No
82	AP4M1	Ap4m1			6468	0.157	0.4546	No
83	CTSZ	Ctsz			6937	0.074	0.4248	No
84	CTSE	Ctse			7356	0.015	0.3978	No
85	ENTPD4	Entpd4b			7512	0.000	0.3878	No
86	AP1M2	Ap1m2			7560	0.000	0.3847	No
87	CTSS	Ctss			7733	0.000	0.3736	No
88	DNASE2B	Dnase2b			7945	0.000	0.3599	No
89	AP3M1	Ap3m1			8328	-0.058	0.3355	No
90	CTSF	Ctsf			9149	-0.203	0.2838	No
91	CLTB	Cltb			9460	-0.261	0.2656	No
92	ARSB	Arsb			9474	-0.265	0.2667	No
93	AP1B1	Ap1b1			9642	-0.299	0.2580	No
94	AP3S2	Ap3s2			10129	-0.396	0.2294	No
95	CTSG	Ctsg			10393	-0.424	0.2154	No
96	NAPSA	Napsa			10421	-0.424	0.2167	No
97	ATP6V0A4	Atp6v0a4			10462	-0.428	0.2173	No
98	PSAPL1	Psapl1			11011	-0.512	0.1854	No
99	AP1S1	Ap1s1			11386	-0.585	0.1654	No
100	ABCB9	Abcb9			11529	-0.624	0.1608	No
101	PPT2	Ppt2			11556	-0.631	0.1637	No
102	AP4S1	Ap4s1			11766	-0.692	0.1551	No
103	LAPTM5	Laptm5			11799	-0.702	0.1582	No
104	AP4B1	Ap4b1			12084	-0.782	0.1454	No
105	AP3B2	Ap3b2			12159	-0.799	0.1464	No
106	AP1S3	Ap1s3			12290	-0.836	0.1441	No
107	GALNS	Galns			12817	-0.977	0.1171	No
108	CTSH	Ctsh			13079	-1.083	0.1080	No
109	SLC11A1	Slc11a1			13350	-1.202	0.0993	No
110	CTSC	Ctsc			13926	-1.547	0.0732	No
111	ATP6V0D2	Atp6v0d2			15409	-4.183	0.0075	No

Fig 2: KEGG_LYSOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_LYSOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_LYSOSOME