Details for gene set KEGG_SPLICEOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_HG.phenotype.cls#NG_versus_HG_repos
Phenotype	phenotype.cls#NG_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_SPLICEOSOME
Enrichment Score (ES)	-0.5617211
Normalized Enrichment Score (NES)	-2.091717
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_SPLICEOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA8	Hspa8			1554	1.517	-0.0843	No
2	BCAS2	Bcas2			3386	0.757	-0.1948	No
3	THOC2	Thoc2			4605	0.490	-0.2685	No
4	TXNL4A	Txnl4a			4707	0.467	-0.2700	No
5	THOC1	Thoc1			4809	0.443	-0.2717	No
6	SLU7	Slu7			4894	0.440	-0.2724	No
7	HSPA2	Hspa2			5179	0.397	-0.2865	No
8	DHX16	Dhx16			5525	0.334	-0.3052	No
9	DHX8	Dhx8			5749	0.291	-0.3165	No
10	SYF2	Syf2			5844	0.277	-0.3196	No
11	U2SURP	U2surp			5903	0.262	-0.3205	No
12	PRPF40B	Prpf40b			6016	0.240	-0.3251	No
13	PUF60	Puf60			6157	0.217	-0.3318	No
14	SF3B3	Sf3b3			6181	0.214	-0.3310	No
15	SF3B2	Sf3b2			6238	0.203	-0.3324	No
16	SNRNP200	Snrnp200			6344	0.182	-0.3373	No
17	RBM8A	Rbm8a			6506	0.150	-0.3461	No
18	SF3B1	Sf3b1			6848	0.088	-0.3672	No
19	PCBP1	Pcbp1			6869	0.085	-0.3676	No
20	SMNDC1	Smndc1			7047	0.060	-0.3784	No
21	CRNKL1	Crnkl1			7359	0.015	-0.3984	No
22	CCDC12	Ccdc12			8084	-0.010	-0.4453	No
23	BUD31	Bud31			8106	-0.014	-0.4465	No
24	PRPF8	Prpf8			8442	-0.078	-0.4674	No
25	DHX38	Dhx38			8476	-0.085	-0.4686	No
26	DDX42	Ddx42			8556	-0.099	-0.4727	No
27	DDX23	Ddx23			8668	-0.120	-0.4786	No
28	PLRG1	Plrg1			8707	-0.127	-0.4797	No
29	DDX39B	Ddx39b			8987	-0.173	-0.4959	No
30	CWC15	Cwc15			9005	-0.176	-0.4950	No
31	CHERP	Cherp			9026	-0.181	-0.4944	No
32	PQBP1	Pqbp1			9107	-0.198	-0.4974	No
33	SNRNP70	Snrnp70			9231	-0.217	-0.5030	No
34	U2AF2	U2af2			9281	-0.227	-0.5037	No
35	ALYREF	4931428L18Rik			9284	-0.228	-0.5014	No
36	SF3B5	Sf3b5			9294	-0.230	-0.4994	No
37	HNRNPK	Hnrnpk			9306	-0.232	-0.4976	No
38	PRPF6	Prpf6			9453	-0.260	-0.5043	No
39	SRSF5	Srsf5			9493	-0.269	-0.5039	No
40	SNRNP27	Snrnp27			9600	-0.292	-0.5076	No
41	RBM22	Rbm22			9795	-0.329	-0.5166	No
42	XAB2	Xab2			9923	-0.358	-0.5209	No
43	AQR	Aqr			10051	-0.381	-0.5250	No
44	ZMAT2	Zmat2			10055	-0.382	-0.5210	No
45	RBM25	Rbm25			10158	-0.405	-0.5232	No
46	SF3A2	Sf3a2			10442	-0.425	-0.5370	No
47	DDX5	Ddx5			10758	-0.469	-0.5523	No
48	SNRPB	Snrpb			10829	-0.485	-0.5515	No
49	PRPF3	Prpf3			10987	-0.507	-0.5562	Yes
50	SF3B6	Sf3b6			11055	-0.518	-0.5549	Yes
51	SF3A1	Sf3a1			11115	-0.528	-0.5530	Yes
52	SF3B4	Sf3b4			11122	-0.530	-0.5476	Yes
53	SNRPC	Snrpc			11171	-0.539	-0.5448	Yes
54	SNW1	Snw1			11362	-0.581	-0.5508	Yes
55	HNRNPA3	Gm17190			11495	-0.613	-0.5527	Yes
56	SNRPF	Snrpf			11551	-0.630	-0.5494	Yes
57	PRPF40A	Prpf40a			11625	-0.648	-0.5471	Yes
58	ACIN1	Acin1			11637	-0.652	-0.5407	Yes
59	CTNNBL1	Ctnnbl1			11698	-0.670	-0.5373	Yes
60	RBM17	Rbm17			11818	-0.706	-0.5373	Yes
61	LSM7	Lsm7			12042	-0.767	-0.5434	Yes
62	SART1	Sart1			12049	-0.769	-0.5354	Yes
63	USP39	Usp39			12104	-0.785	-0.5304	Yes
64	DDX46	Ddx46			12154	-0.798	-0.5248	Yes
65	NCBP1	Ncbp1			12156	-0.799	-0.5162	Yes
66	MAGOH	Magoh			12229	-0.815	-0.5120	Yes
67	LSM4	Lsm4			12356	-0.850	-0.5109	Yes
68	LSM8	Lsm8			12395	-0.858	-0.5040	Yes
69	CDC5L	Cdc5l			12402	-0.860	-0.4950	Yes
70	PRPF19	Prpf19			12544	-0.891	-0.4945	Yes
71	PHF5A	Phf5a			12570	-0.899	-0.4863	Yes
72	SNRPD3	Snrpd3			12668	-0.931	-0.4824	Yes
73	PRPF38A	Prpf38a			12700	-0.941	-0.4742	Yes
74	CDC40	Cdc40			12762	-0.961	-0.4677	Yes
75	PPIE	Ppie			12879	-1.001	-0.4643	Yes
76	EFTUD2	Eftud2			12956	-1.029	-0.4580	Yes
77	SRSF4	Srsf4			12990	-1.038	-0.4488	Yes
78	SNU13	Snu13			13006	-1.047	-0.4384	Yes
79	DHX15	Dhx15			13011	-1.049	-0.4272	Yes
80	SNRPD2	Snrpd2			13140	-1.108	-0.4234	Yes
81	SNRPB2	Snrpb2			13185	-1.124	-0.4140	Yes
82	HNRNPM	Hnrnpm			13324	-1.190	-0.4100	Yes
83	HNRNPU	Hnrnpu			13343	-1.200	-0.3981	Yes
84	SRSF9	Srsf9			13381	-1.221	-0.3872	Yes
85	RBMX	Rbmx			13406	-1.234	-0.3753	Yes
86	SRSF10	Srsf10			13410	-1.236	-0.3620	Yes
87	NCBP2	Ncbp2			13489	-1.273	-0.3532	Yes
88	LSM2	Lsm2			13494	-1.276	-0.3395	Yes
89	PRPF31	Prpf31			13561	-1.321	-0.3294	Yes
90	SRSF6	Srsf6			13590	-1.336	-0.3167	Yes
91	SF3A3	Sf3a3			13593	-1.337	-0.3022	Yes
92	LSM6	Lsm6			13610	-1.347	-0.2886	Yes
93	TRA2A	Tra2a			13627	-1.353	-0.2749	Yes
94	SNRPA	Snrpa			13628	-1.354	-0.2601	Yes
95	PRPF4	Prpf4			13702	-1.394	-0.2496	Yes
96	SNRPG	Snrpg			13724	-1.411	-0.2356	Yes
97	EIF4A3	Eif4a3			13727	-1.413	-0.2204	Yes
98	THOC3	Thoc3			13735	-1.418	-0.2054	Yes
99	TCERG1	Tcerg1			13803	-1.452	-0.1939	Yes
100	TRA2B	Tra2b			13936	-1.555	-0.1855	Yes
101	SNRPD1	Snrpd1			14045	-1.631	-0.1747	Yes
102	SRSF3	Srsf3			14088	-1.666	-0.1593	Yes
103	PPIH	Gm7879			14195	-1.753	-0.1470	Yes
104	SNRNP40	Snrnp40			14271	-1.824	-0.1320	Yes
105	HNRNPA1	Hnrnpa1			14299	-1.853	-0.1136	Yes
106	SRSF2	Srsf2			14402	-1.967	-0.0988	Yes
107	LSM5	Lsm5			14405	-1.970	-0.0774	Yes
108	PPIL1	Ppil1			14491	-2.090	-0.0601	Yes
109	MAGOHB	Magohb			14494	-2.091	-0.0375	Yes
110	SRSF7	Srsf7			14638	-2.310	-0.0216	Yes
111	SNRPA1	Snrpa1			14641	-2.317	0.0035	Yes
112	HSPA1L	Hspa1l			14668	-2.365	0.0276	Yes
113	LSM3	Lsm3			14798	-2.560	0.0472	Yes

Fig 2: KEGG_SPLICEOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_SPLICEOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_SPLICEOSOME