Details for gene set KEGG_ACUTE_MYELOID_LEUKEMIA[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	NG
GeneSet	KEGG_ACUTE_MYELOID_LEUKEMIA
Enrichment Score (ES)	0.38200873
Normalized Enrichment Score (NES)	1.4595947
Nominal p-value	0.028571429
FDR q-value	0.24016757
FWER p-Value	0.861

Fig 1: Enrichment plot: KEGG_ACUTE_MYELOID_LEUKEMIA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	LEF1	Lef1			66	2.806	0.0855	Yes
2	PIM1	Pim1			535	1.638	0.1076	Yes
3	STAT3	Stat3			765	1.428	0.1385	Yes
4	JUP	Jup			978	1.288	0.1660	Yes
5	IKBKG	Ikbkg			1409	1.077	0.1727	Yes
6	FLT3	Flt3			1413	1.075	0.2069	Yes
7	BRAF	Braf			2012	0.871	0.1961	Yes
8	ZBTB16	Zbtb16			2038	0.862	0.2220	Yes
9	CHUK	Chuk			2135	0.833	0.2425	Yes
10	RUNX1	Runx1			2285	0.790	0.2581	Yes
11	SOS2	Sos2			2309	0.784	0.2817	Yes
12	IKBKB	Ikbkb			2340	0.774	0.3045	Yes
13	PIK3CA	Pik3ca			2701	0.689	0.3033	Yes
14	STAT5A	Stat5a			2967	0.636	0.3065	Yes
15	NRAS	Nras			3047	0.622	0.3212	Yes
16	PIM2	Pim2			3253	0.580	0.3265	Yes
17	PPARD	Ppard			3275	0.576	0.3436	Yes
18	MAPK3	Mapk3			3365	0.559	0.3557	Yes
19	MAP2K1	Map2k1			3446	0.545	0.3680	Yes
20	KIT	Kit			3495	0.536	0.3820	Yes
21	ARAF	Araf			3998	0.466	0.3645	No
22	RELA	Rela			4444	0.415	0.3490	No
23	TCF7L1	Tcf7l1			4772	0.364	0.3395	No
24	RARA	Rara			5164	0.302	0.3239	No
25	MTOR	Mtor			5411	0.266	0.3165	No
26	PIK3CG	Pik3cg			5708	0.224	0.3045	No
27	CEBPA	Cebpa			6047	0.172	0.2882	No
28	SOS1	Sos1			6149	0.157	0.2867	No
29	PIK3CD	Pik3cd			6360	0.128	0.2772	No
30	AKT1	Akt1			6815	0.066	0.2500	No
31	AKT2	Akt2			6903	0.054	0.2461	No
32	CCNA1	Ccna1			6907	0.054	0.2476	No
33	EIF4EBP1	Eif4ebp1			7045	0.036	0.2399	No
34	SPI1	Spi1			7947	-0.013	0.1821	No
35	STAT5B	Stat5b			8034	-0.028	0.1774	No
36	AKT3	Akt3			8066	-0.032	0.1765	No
37	PIK3R5	Pik3r5			9023	-0.172	0.1202	No
38	KRAS	Kras			9184	-0.193	0.1160	No
39	TCF7	Tcf7			9466	-0.237	0.1054	No
40	PIK3CB	Pik3cb			9473	-0.238	0.1127	No
41	MAPK1	Mapk1			9523	-0.246	0.1174	No
42	RPS6KB2	Rps6kb2			9526	-0.247	0.1252	No
43	BAD	Bad			9962	-0.319	0.1073	No
44	GRB2	Grb2			10985	-0.438	0.0552	No
45	TCF7L2	Tcf7l2			11083	-0.458	0.0636	No
46	NFKB1	Nfkb1			11113	-0.463	0.0766	No
47	RAF1	Raf1			11324	-0.492	0.0787	No
48	PIK3R1	Pik3r1			11750	-0.565	0.0693	No
49	HRAS	Hras			12226	-0.666	0.0599	No
50	RUNX1T1	Runx1t1			13312	-0.930	0.0196	No
51	PML	Pml			13446	-0.977	0.0422	No
52	MYC	Myc			13868	-1.132	0.0512	No
53	CCND1	Ccnd1			14737	-1.745	0.0509	No

Fig 2: KEGG_ACUTE_MYELOID_LEUKEMIA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_ACUTE_MYELOID_LEUKEMIA: Random ES distribution   
Gene set null distribution of ES for KEGG_ACUTE_MYELOID_LEUKEMIA