Details for gene set KEGG_CELL_CYCLE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_CELL_CYCLE
Enrichment Score (ES)	-0.66441554
Normalized Enrichment Score (NES)	-2.4965672
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_CELL_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GADD45A	Gadd45a			138	2.445	0.0072	No
2	EP300	Ep300			1298	1.118	-0.0606	No
3	CREBBP	Crebbp			1430	1.067	-0.0621	No
4	PRKDC	Prkdc			1452	1.053	-0.0565	No
5	MDM2	Mdm2			1537	1.023	-0.0552	No
6	SMAD2	Smad2			1612	0.997	-0.0534	No
7	RB1	Rb1			1789	0.937	-0.0586	No
8	GSK3B	Gsk3b			1956	0.881	-0.0636	No
9	ZBTB17	Zbtb17			2221	0.808	-0.0754	No
10	SMAD3	Smad3			3030	0.624	-0.1237	No
11	STAG2	Stag2			3198	0.591	-0.1306	No
12	RBL2	Rbl2			3936	0.479	-0.1753	No
13	SFN	Sfn			3965	0.473	-0.1740	No
14	ATM	Atm			3970	0.472	-0.1711	No
15	YWHAG	Ywhag			4047	0.457	-0.1730	No
16	SMAD4	Smad4			4050	0.456	-0.1701	No
17	ANAPC2	Anapc2			4539	0.399	-0.1992	No
18	SMC1B	Smc1b			5391	0.269	-0.2526	No
19	CDC27	Cdc27			6079	0.168	-0.2961	No
20	STAG1	Stag1			6631	0.087	-0.3313	No
21	YWHAB	Ywhab			6783	0.071	-0.3406	No
22	CCNA1	Ccna1			6907	0.054	-0.3482	No
23	CDKN1A	Cdkn1a			7037	0.037	-0.3564	No
24	YWHAZ	Ywhaz			7048	0.035	-0.3568	No
25	SKP1	Skp1a			7090	0.030	-0.3592	No
26	YWHAH	Ywhah			7223	0.013	-0.3677	No
27	WEE2	Wee2			7407	0.000	-0.3796	No
28	ORC3	Orc3			7874	-0.004	-0.4098	No
29	ORC4	Orc4			8098	-0.037	-0.4240	No
30	CDKN1B	Cdkn1b			8161	-0.049	-0.4277	No
31	CDC16	Cdc16			8209	-0.055	-0.4304	No
32	ANAPC1	Anapc1			8269	-0.063	-0.4338	No
33	ABL1	Abl1			8308	-0.068	-0.4358	No
34	CDK4	Cdk4			8434	-0.086	-0.4434	No
35	CCNB3	Ccnb3			8694	-0.120	-0.4594	No
36	CCNH	Ccnh			8891	-0.150	-0.4711	No
37	CDK6	Cdk6			8988	-0.167	-0.4763	No
38	CUL1	Cul1			9002	-0.169	-0.4760	No
39	RBX1	Rbx1			9172	-0.192	-0.4857	No
40	ANAPC4	Anapc4			9239	-0.203	-0.4886	No
41	GADD45B	Gadd45b			9269	-0.208	-0.4891	No
42	MAD2L2	Mad2l2			9318	-0.215	-0.4908	No
43	ANAPC10	Anapc10			9369	-0.222	-0.4926	No
44	TGFB1	Tgfb1			9531	-0.248	-0.5014	No
45	E2F5	E2f5			9690	-0.273	-0.5099	No
46	ANAPC13	Anapc13			9706	-0.275	-0.5090	No
47	PCNA	Pcna			9987	-0.323	-0.5251	No
48	CDC14A	Cdc14a			10062	-0.335	-0.5277	No
49	YWHAQ	Ywhaq			10336	-0.378	-0.5429	No
50	ANAPC5	Anapc5			10481	-0.403	-0.5496	No
51	WEE1	Wee1			10607	-0.407	-0.5550	No
52	YWHAE	Ywhae			10626	-0.410	-0.5535	No
53	CCND3	Ccnd3			11075	-0.456	-0.5795	No
54	CDC26	Cdc26			11327	-0.492	-0.5925	No
55	TP53	Trp53			11444	-0.509	-0.5967	No
56	ANAPC7	Anapc7			11602	-0.536	-0.6034	No
57	TGFB3	Tgfb3			11679	-0.551	-0.6047	No
58	ATR	Atr			11688	-0.552	-0.6015	No
59	CDK7	Cdk7			11720	-0.558	-0.5998	No
60	E2F3	E2f3			11884	-0.589	-0.6065	No
61	HDAC2	Hdac2			11993	-0.613	-0.6095	No
62	TFDP2	Tfdp2			12135	-0.645	-0.6144	No
63	BUB3	Bub3			12483	-0.725	-0.6321	No
64	SMC1A	Smc1a			12518	-0.735	-0.6295	No
65	CDC25B	Cdc25b			12556	-0.742	-0.6270	No
66	CDK2	Cdk2			12758	-0.793	-0.6348	No
67	SMC3	Smc3			12802	-0.803	-0.6322	No
68	HDAC1	Hdac1			12879	-0.822	-0.6317	No
69	E2F1	E2f1			12995	-0.843	-0.6336	No
70	MAD1L1	Mad1l1			13237	-0.908	-0.6433	No
71	FZR1	Fzr1			13239	-0.909	-0.6373	No
72	E2F4	E2f4			13264	-0.916	-0.6328	No
73	TGFB2	Tgfb2			13723	-1.076	-0.6555	No
74	TFDP1	Tfdp1			13862	-1.129	-0.6570	Yes
75	MYC	Myc			13868	-1.132	-0.6498	Yes
76	RAD21	Rad21			13990	-1.198	-0.6497	Yes
77	GADD45G	Gadd45g			14056	-1.231	-0.6458	Yes
78	CHEK2	Chek2			14135	-1.288	-0.6424	Yes
79	CDC25A	Cdc25a			14138	-1.288	-0.6340	Yes
80	CDC23	Cdc23			14171	-1.301	-0.6275	Yes
81	ORC5	Orc5			14635	-1.638	-0.6467	Yes
82	CCND1	Ccnd1			14737	-1.745	-0.6417	Yes
83	CDC7	Cdc7			14770	-1.789	-0.6320	Yes
84	CDKN1C	Cdkn1c			14804	-1.837	-0.6220	Yes
85	DBF4	Dbf4			14815	-1.845	-0.6105	Yes
86	MCM2	Mcm2			14826	-1.855	-0.5988	Yes
87	MCM7	Mcm7			14857	-1.897	-0.5883	Yes
88	MCM4	Mcm4			14859	-1.899	-0.5758	Yes
89	E2F2	E2f2			14911	-1.981	-0.5660	Yes
90	ORC2	Orc2			14916	-1.993	-0.5531	Yes
91	ORC6	Orc6			14956	-2.061	-0.5420	Yes
92	SKP2	Skp2			15030	-2.197	-0.5322	Yes
93	PKMYT1	Pkmyt1			15075	-2.298	-0.5199	Yes
94	CDKN2D	Cdkn2d			15100	-2.346	-0.5060	Yes
95	MCM3	Mcm3			15264	-2.840	-0.4978	Yes
96	MCM6	Mcm6			15281	-2.888	-0.4797	Yes
97	RBL1	Rbl1			15283	-2.888	-0.4607	Yes
98	ORC1	Orc1			15289	-2.913	-0.4418	Yes
99	CDKN2C	Cdkn2c			15298	-2.981	-0.4226	Yes
100	MAD2L1	Mad2l1			15332	-3.170	-0.4038	Yes
101	CDK1	Cdk1			15355	-3.325	-0.3833	Yes
102	CDC45	Cdc45			15358	-3.330	-0.3614	Yes
103	CHEK1	Chek1			15360	-3.334	-0.3395	Yes
104	CCNE1	Ccne1			15413	-3.704	-0.3184	Yes
105	MCM5	Mcm5			15418	-3.742	-0.2939	Yes
106	CCNE2	Ccne2			15435	-3.837	-0.2696	Yes
107	CDC25C	Cdc25c			15466	-3.990	-0.2452	Yes
108	CCNB1	Ccnb1			15467	-3.995	-0.2188	Yes
109	ESPL1	Espl1			15479	-4.062	-0.1927	Yes
110	CCNB2	Ccnb2			15480	-4.070	-0.1658	Yes
111	CDC20	Cdc20			15495	-4.143	-0.1393	Yes
112	BUB1	Bub1			15497	-4.158	-0.1119	Yes
113	CDC6	Cdc6			15498	-4.172	-0.0844	Yes
114	TTK	Ttk			15511	-4.266	-0.0570	Yes
115	CCNA2	Ccna2			15519	-4.320	-0.0289	Yes
116	PLK1	Plk1			15522	-4.422	0.0002	Yes

Fig 2: KEGG_CELL_CYCLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_CELL_CYCLE: Random ES distribution   
Gene set null distribution of ES for KEGG_CELL_CYCLE