Details for gene set KEGG_LYSOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	NG
GeneSet	KEGG_LYSOSOME
Enrichment Score (ES)	0.48889416
Normalized Enrichment Score (NES)	2.1438372
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_LYSOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MCOLN1	Mcoln1			230	2.159	0.0113	Yes
2	NEU1	Neu1			344	1.904	0.0271	Yes
3	CTNS	Ctns			414	1.772	0.0441	Yes
4	GLA	Gla			424	1.761	0.0649	Yes
5	GNPTG	Gnptg			446	1.728	0.0845	Yes
6	ATP6V0B	Atp6v0b			461	1.713	0.1044	Yes
7	CTSA	Ctsa			555	1.617	0.1180	Yes
8	SLC17A5	Slc17a5			579	1.586	0.1358	Yes
9	TPP1	Tpp1			607	1.556	0.1529	Yes
10	GBA	Gba			647	1.520	0.1688	Yes
11	IGF2R	Igf2r			659	1.509	0.1864	Yes
12	LAMP1	Lamp1			672	1.494	0.2038	Yes
13	CTSK	Ctsk			787	1.417	0.2136	Yes
14	LAPTM5	Laptm5			795	1.412	0.2303	Yes
15	ARSA	Arsa			827	1.387	0.2451	Yes
16	NPC1	Npc1			903	1.334	0.2565	Yes
17	ATP6V0D1	Atp6v0d1			1008	1.261	0.2650	Yes
18	MAN2B1	Man2b1			1048	1.239	0.2775	Yes
19	ATP6V0C	Atp6v0c			1123	1.204	0.2874	Yes
20	CTSF	Ctsf			1185	1.171	0.2976	Yes
21	CLTC	Cltc			1190	1.168	0.3115	Yes
22	LAMP2	Lamp2			1266	1.130	0.3204	Yes
23	ASAH1	Asah1			1285	1.123	0.3329	Yes
24	AP3D1	Ap3d1			1287	1.123	0.3464	Yes
25	ATP6AP1	Atp6ap1			1516	1.032	0.3442	Yes
26	GGA2	Gga2			1575	1.010	0.3527	Yes
27	HYAL1	Hyal1			1635	0.988	0.3608	Yes
28	GNS	Gns			1679	0.968	0.3698	Yes
29	PPT1	Ppt1			1690	0.965	0.3809	Yes
30	ACP5	Acp5			1763	0.943	0.3876	Yes
31	NAGPA	Nagpa			1929	0.891	0.3878	Yes
32	SUMF1	Sumf1			1941	0.887	0.3978	Yes
33	MANBA	Manba			2017	0.869	0.4035	Yes
34	MFSD8	Mfsd8			2037	0.862	0.4127	Yes
35	AP3B1	Ap3b1			2100	0.843	0.4189	Yes
36	HEXB	Hexb			2158	0.828	0.4253	Yes
37	GAA	Gaa			2210	0.813	0.4319	Yes
38	NPC2	Npc2			2240	0.804	0.4397	Yes
39	LAPTM4B	Laptm4b			2287	0.789	0.4463	Yes
40	ATP6V1H	Atp6v1h			2325	0.779	0.4534	Yes
41	PSAP	Psap			2357	0.769	0.4607	Yes
42	LAPTM4A	Laptm4a			2361	0.769	0.4699	Yes
43	ABCA2	Abca2			2376	0.763	0.4782	Yes
44	GGA3	Gga3			2418	0.752	0.4847	Yes
45	TCIRG1	Tcirg1			2492	0.736	0.4889	Yes
46	GLB1	Glb1			2923	0.644	0.4688	No
47	CD63	Cd63			3173	0.595	0.4599	No
48	CD164	Cd164			3235	0.584	0.4630	No
49	LIPA	Lipa			3243	0.582	0.4696	No
50	AP4E1	Ap4e1			3251	0.581	0.4762	No
51	LGMN	Lgmn			3386	0.554	0.4743	No
52	AP3S1	Ap3s1			3468	0.540	0.4756	No
53	IDUA	Idua			3610	0.519	0.4727	No
54	AP1S2	Ap1s2			3670	0.509	0.4751	No
55	DNASE2	Dnase2a			3896	0.487	0.4664	No
56	AGA	Aga			4011	0.463	0.4646	No
57	AP1G1	Ap1g1			4013	0.463	0.4702	No
58	CTSB	Ctsb			4024	0.461	0.4751	No
59	AP4B1	Ap4b1			4145	0.443	0.4727	No
60	FUCA1	Fuca1			4326	0.433	0.4663	No
61	ATP6V0A1	Atp6v0a1			4347	0.429	0.4702	No
62	GALC	Galc			4571	0.394	0.4606	No
63	AP4M1	Ap4m1			4624	0.386	0.4619	No
64	SCARB2	Scarb2			4686	0.377	0.4625	No
65	SORT1	Sort1			4763	0.365	0.4620	No
66	GGA1	Gga1			5075	0.316	0.4456	No
67	SMPD1	Smpd1			5207	0.294	0.4407	No
68	CLTA	Clta			5390	0.270	0.4322	No
69	CTSE	Ctse			5613	0.236	0.4206	No
70	AP1M1	Ap1m1			5998	0.178	0.3979	No
71	ACP2	Acp2			6005	0.177	0.3997	No
72	M6PR	M6pr			6087	0.166	0.3964	No
73	GM2A	Gm2a			6123	0.159	0.3961	No
74	GNPTAB	Gnptab			6174	0.153	0.3947	No
75	PSAPL1	Psapl1			7441	0.000	0.3126	No
76	CTSS	Ctss			7567	0.000	0.3045	No
77	ARSG	Arsg			8116	-0.040	0.2694	No
78	CTSZ	Ctsz			8168	-0.050	0.2667	No
79	HGSNAT	Hgsnat			8776	-0.132	0.2289	No
80	SGSH	Sgsh			8807	-0.137	0.2287	No
81	NAGA	Naga			8818	-0.138	0.2297	No
82	ABCB9	Abcb9			8930	-0.156	0.2244	No
83	AP1B1	Ap1b1			9007	-0.169	0.2215	No
84	AP3M2	Ap3m2			9012	-0.171	0.2233	No
85	GUSB	Gusb			9055	-0.176	0.2227	No
86	SLC11A1	Slc11a1			9497	-0.242	0.1971	No
87	CTSO	Ctso			9560	-0.252	0.1961	No
88	ATP6V0A2	Atp6v0a2			9618	-0.261	0.1956	No
89	AP1S3	Ap1s3			9711	-0.276	0.1930	No
90	AP1M2	Ap1m2			10523	-0.407	0.1453	No
91	NAPSA	Napsa			10582	-0.407	0.1465	No
92	AP3M1	Ap3m1			10666	-0.417	0.1461	No
93	DNASE2B	Dnase2b			10771	-0.421	0.1445	No
94	SLC11A2	Slc11a2			10801	-0.423	0.1478	No
95	ENTPD4	Entpd4b			10870	-0.432	0.1486	No
96	CTSG	Ctsg			10898	-0.432	0.1521	No
97	PLA2G15	Pla2g15			11378	-0.496	0.1270	No
98	AP1S1	Ap1s1			11658	-0.547	0.1156	No
99	CTSC	Ctsc			11920	-0.595	0.1059	No
100	CTSH	Ctsh			11930	-0.597	0.1125	No
101	CTSW	Ctsw			12042	-0.625	0.1129	No
102	AP3S2	Ap3s2			12122	-0.642	0.1156	No
103	NAGLU	Naglu			12145	-0.646	0.1220	No
104	ARSB	Arsb			12501	-0.730	0.1078	No
105	AP3B2	Ap3b2			12511	-0.733	0.1162	No
106	PPT2	Ppt2			12551	-0.741	0.1226	No
107	GALNS	Galns			12731	-0.789	0.1206	No
108	CLTB	Cltb			12792	-0.801	0.1264	No
109	AP4S1	Ap4s1			13153	-0.886	0.1138	No
110	ATP6V0A4	Atp6v0a4			13667	-1.055	0.0934	No
111	ATP6V0D2	Atp6v0d2			15045	-2.233	0.0311	No

Fig 2: KEGG_LYSOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_LYSOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_LYSOSOME