Details for gene set KEGG_SPLICEOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_SPLICEOSOME
Enrichment Score (ES)	-0.50180817
Normalized Enrichment Score (NES)	-1.8729767
Nominal p-value	0.0
FDR q-value	0.004560605
FWER p-Value	0.043

Fig 1: Enrichment plot: KEGG_SPLICEOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA8	Hspa8			581	1.581	-0.0167	No
2	THOC2	Thoc2			1188	1.169	-0.0404	No
3	SRSF5	Srsf5			2594	0.715	-0.1221	No
4	PRPF40B	Prpf40b			2903	0.648	-0.1334	No
5	SF3B1	Sf3b1			3220	0.586	-0.1461	No
6	DHX8	Dhx8			3429	0.547	-0.1523	No
7	THOC1	Thoc1			3622	0.518	-0.1579	No
8	SYF2	Syf2			4086	0.450	-0.1820	No
9	SLU7	Slu7			4678	0.379	-0.2153	No
10	HSPA2	Hspa2			4685	0.377	-0.2106	No
11	BCAS2	Bcas2			4712	0.374	-0.2074	No
12	SF3B3	Sf3b3			4908	0.340	-0.2155	No
13	SNRNP200	Snrnp200			5077	0.316	-0.2222	No
14	U2SURP	U2surp			5206	0.294	-0.2266	No
15	PUF60	Puf60			5409	0.267	-0.2361	No
16	CRNKL1	Crnkl1			5553	0.246	-0.2421	No
17	DHX16	Dhx16			5695	0.226	-0.2483	No
18	PCBP1	Pcbp1			5710	0.224	-0.2462	No
19	SF3B2	Sf3b2			5884	0.195	-0.2548	No
20	DDX42	Ddx42			5911	0.191	-0.2540	No
21	PRPF8	Prpf8			6179	0.152	-0.2693	No
22	SNRNP70	Snrnp70			6199	0.150	-0.2685	No
23	PRPF6	Prpf6			6371	0.126	-0.2779	No
24	DHX38	Dhx38			6451	0.114	-0.2815	No
25	TXNL4A	Txnl4a			6733	0.078	-0.2987	No
26	HNRNPK	Hnrnpk			6849	0.059	-0.3054	No
27	XAB2	Xab2			7057	0.034	-0.3184	No
28	SMNDC1	Smndc1			7226	0.012	-0.3291	No
29	PLRG1	Plrg1			7964	-0.016	-0.3767	No
30	DDX23	Ddx23			8103	-0.038	-0.3852	No
31	ACIN1	Acin1			8122	-0.042	-0.3858	No
32	AQR	Aqr			8611	-0.109	-0.4160	No
33	DDX39B	Ddx39b			8645	-0.114	-0.4166	No
34	PQBP1	Pqbp1			8649	-0.114	-0.4153	No
35	CHERP	Cherp			8858	-0.145	-0.4268	No
36	BUD31	Bud31			9019	-0.172	-0.4349	No
37	ALYREF	4931428L18Rik			9037	-0.175	-0.4337	No
38	HNRNPA3	Gm17190			9142	-0.187	-0.4380	No
39	CCDC12	Ccdc12			9500	-0.242	-0.4579	No
40	U2AF2	U2af2			9535	-0.248	-0.4568	No
41	DDX5	Ddx5			9538	-0.249	-0.4536	No
42	SNW1	Snw1			9624	-0.262	-0.4557	No
43	CWC15	Cwc15			9667	-0.269	-0.4548	No
44	RBM22	Rbm22			9703	-0.274	-0.4534	No
45	CTNNBL1	Ctnnbl1			9864	-0.300	-0.4598	No
46	CDC40	Cdc40			10027	-0.330	-0.4659	No
47	RBM25	Rbm25			10242	-0.363	-0.4750	No
48	CDC5L	Cdc5l			10322	-0.374	-0.4751	No
49	SF3A1	Sf3a1			10383	-0.386	-0.4739	No
50	SF3A2	Sf3a2			10405	-0.390	-0.4701	No
51	SNRPB	Snrpb			10415	-0.392	-0.4654	No
52	PRPF40A	Prpf40a			10447	-0.397	-0.4622	No
53	SRSF4	Srsf4			10795	-0.423	-0.4791	No
54	SNRPC	Snrpc			11081	-0.457	-0.4915	No
55	RBM8A	Rbm8a			11090	-0.460	-0.4859	No
56	SF3B4	Sf3b4			11215	-0.478	-0.4875	No
57	SART1	Sart1			11436	-0.508	-0.4950	Yes
58	SF3B5	Sf3b5			11440	-0.509	-0.4885	Yes
59	NCBP1	Ncbp1			11523	-0.521	-0.4869	Yes
60	RBM17	Rbm17			11618	-0.538	-0.4858	Yes
61	ZMAT2	Zmat2			11670	-0.549	-0.4818	Yes
62	TRA2A	Tra2a			11696	-0.555	-0.4760	Yes
63	DHX15	Dhx15			11778	-0.568	-0.4737	Yes
64	SNRNP27	Snrnp27			11869	-0.585	-0.4718	Yes
65	PRPF3	Prpf3			11874	-0.588	-0.4642	Yes
66	DDX46	Ddx46			11922	-0.595	-0.4593	Yes
67	HNRNPM	Hnrnpm			11967	-0.605	-0.4541	Yes
68	SRSF6	Srsf6			12066	-0.629	-0.4521	Yes
69	LSM8	Lsm8			12217	-0.664	-0.4530	Yes
70	SF3B6	Sf3b6			12220	-0.665	-0.4443	Yes
71	PRPF19	Prpf19			12234	-0.668	-0.4362	Yes
72	SNRPD3	Snrpd3			12260	-0.675	-0.4289	Yes
73	HNRNPU	Hnrnpu			12289	-0.681	-0.4216	Yes
74	SRSF9	Srsf9			12322	-0.687	-0.4146	Yes
75	PPIE	Ppie			12426	-0.713	-0.4118	Yes
76	MAGOH	Magoh			12457	-0.718	-0.4041	Yes
77	SNRPD2	Snrpd2			12592	-0.751	-0.4029	Yes
78	LSM4	Lsm4			12616	-0.760	-0.3942	Yes
79	TCERG1	Tcerg1			12670	-0.774	-0.3874	Yes
80	EFTUD2	Eftud2			12716	-0.784	-0.3798	Yes
81	SNRPG	Snrpg			12800	-0.802	-0.3746	Yes
82	SRSF10	Srsf10			12883	-0.823	-0.3689	Yes
83	LSM7	Lsm7			12885	-0.823	-0.3580	Yes
84	SNRPB2	Snrpb2			12923	-0.828	-0.3494	Yes
85	SF3A3	Sf3a3			13253	-0.914	-0.3586	Yes
86	SNU13	Snu13			13339	-0.943	-0.3516	Yes
87	NCBP2	Ncbp2			13427	-0.972	-0.3443	Yes
88	SRSF2	Srsf2			13519	-1.004	-0.3368	Yes
89	PRPF38A	Prpf38a			13568	-1.018	-0.3264	Yes
90	PHF5A	Phf5a			13591	-1.027	-0.3141	Yes
91	USP39	Usp39			13682	-1.060	-0.3059	Yes
92	EIF4A3	Eif4a3			13687	-1.062	-0.2920	Yes
93	SNRPA	Snrpa			13700	-1.069	-0.2785	Yes
94	THOC3	Thoc3			13797	-1.103	-0.2701	Yes
95	SNRPF	Snrpf			13810	-1.109	-0.2561	Yes
96	HNRNPA1	Hnrnpa1			13833	-1.118	-0.2427	Yes
97	LSM6	Lsm6			13880	-1.138	-0.2305	Yes
98	PRPF4	Prpf4			13916	-1.159	-0.2173	Yes
99	SNRPD1	Snrpd1			14055	-1.231	-0.2099	Yes
100	SRSF3	Srsf3			14117	-1.277	-0.1969	Yes
101	LSM2	Lsm2			14186	-1.310	-0.1839	Yes
102	TRA2B	Tra2b			14272	-1.361	-0.1713	Yes
103	RBMX	Rbmx			14283	-1.368	-0.1537	Yes
104	PPIH	Gm7879			14368	-1.432	-0.1401	Yes
105	PRPF31	Prpf31			14414	-1.464	-0.1235	Yes
106	SRSF7	Srsf7			14449	-1.485	-0.1060	Yes
107	HSPA1L	Hspa1l			14505	-1.535	-0.0891	Yes
108	LSM5	Lsm5			14532	-1.557	-0.0701	Yes
109	SNRNP40	Snrnp40			14546	-1.566	-0.0501	Yes
110	MAGOHB	Magohb			14844	-1.880	-0.0443	Yes
111	LSM3	Lsm3			14909	-1.980	-0.0221	Yes
112	PPIL1	Ppil1			14919	-2.007	0.0040	Yes
113	SNRPA1	Snrpa1			15208	-2.649	0.0206	Yes

Fig 2: KEGG_SPLICEOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_SPLICEOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_SPLICEOSOME