Details for gene set KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	NG
GeneSet	KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	0.32177448
Normalized Enrichment Score (NES)	1.3420866
Nominal p-value	0.037037037
FDR q-value	0.34374216
FWER p-Value	0.989

Fig 1: Enrichment plot: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	Fos			10	3.554	0.0585	Yes
2	CD28	Cd28			36	3.072	0.1079	Yes
3	TEC	Tec			115	2.521	0.1448	Yes
4	NFAT5	Nfat5			234	2.145	0.1728	Yes
5	CBLB	Cblb			457	1.718	0.1870	Yes
6	LAT	Lat			485	1.685	0.2133	Yes
7	IL4	Il4			898	1.337	0.2088	Yes
8	MAP3K8	Map3k8			1272	1.127	0.2034	Yes
9	IKBKG	Ikbkg			1409	1.077	0.2125	Yes
10	DLG1	Dlg1			1479	1.044	0.2254	Yes
11	NCK2	Nck2			1490	1.041	0.2420	Yes
12	PLCG1	Plcg1			1638	0.987	0.2489	Yes
13	CBL	Cbl			1669	0.972	0.2631	Yes
14	GSK3B	Gsk3b			1956	0.881	0.2592	Yes
15	CD247	Cd247			1975	0.880	0.2727	Yes
16	VAV3	Vav3			2111	0.838	0.2779	Yes
17	CHUK	Chuk			2135	0.833	0.2902	Yes
18	CHP1	Chp1			2165	0.825	0.3021	Yes
19	SOS2	Sos2			2309	0.784	0.3059	Yes
20	IKBKB	Ikbkb			2340	0.774	0.3168	Yes
21	BCL10	Bcl10			2567	0.719	0.3141	Yes
22	PIK3CA	Pik3ca			2701	0.689	0.3169	Yes
23	MALT1	Malt1			2799	0.670	0.3218	Yes
24	NRAS	Nras			3047	0.622	0.3161	No
25	MAPK3	Mapk3			3365	0.559	0.3049	No
26	MAP2K7	Map2k7			3381	0.555	0.3131	No
27	MAP2K1	Map2k1			3446	0.545	0.3180	No
28	TNF	Tnf			3722	0.501	0.3085	No
29	IL10	Il10			3775	0.499	0.3135	No
30	CARD11	Card11			3801	0.498	0.3201	No
31	ICOS	Icos			4155	0.443	0.3046	No
32	RELA	Rela			4444	0.415	0.2929	No
33	PDPK1	Pdpk1			4500	0.406	0.2960	No
34	NFKBIE	Nfkbie			4905	0.341	0.2755	No
35	NFATC4	Nfatc4			5131	0.307	0.2661	No
36	PPP3CA	Ppp3ca			5291	0.283	0.2605	No
37	PIK3CG	Pik3cg			5708	0.224	0.2372	No
38	CSF2	Csf2			5895	0.193	0.2284	No
39	NFKBIA	Nfkbia			5932	0.188	0.2292	No
40	ITK	Itk			5964	0.182	0.2302	No
41	PPP3CB	Ppp3cb			6122	0.159	0.2227	No
42	MAP3K7	Map3k7			6144	0.157	0.2239	No
43	SOS1	Sos1			6149	0.157	0.2263	No
44	IL2	Il2			6260	0.141	0.2215	No
45	PIK3CD	Pik3cd			6360	0.128	0.2172	No
46	NCK1	Nck1			6537	0.100	0.2075	No
47	CBLC	Cblc			6672	0.082	0.2001	No
48	RHOA	Rhoa			6731	0.078	0.1977	No
49	AKT1	Akt1			6815	0.066	0.1934	No
50	MAPK12	Mapk12			6820	0.065	0.1942	No
51	AKT2	Akt2			6903	0.054	0.1898	No
52	NFATC3	Nfatc3			6904	0.054	0.1907	No
53	NFATC1	Nfatc1			6933	0.051	0.1897	No
54	CD4	Cd4			7004	0.044	0.1859	No
55	CHP2	Chp2			7370	0.000	0.1623	No
56	VAV1	Vav1			7404	0.000	0.1601	No
57	PPP3R2	Ppp3r2			7574	0.000	0.1492	No
58	PRKCQ	Prkcq			7610	0.000	0.1469	No
59	PAK5	Pak7			7701	0.000	0.1411	No
60	CTLA4	Ctla4			7808	0.000	0.1342	No
61	AKT3	Akt3			8066	-0.032	0.1181	No
62	CDK4	Cdk4			8434	-0.086	0.0957	No
63	CDC42	Cdc42			8435	-0.086	0.0972	No
64	RASGRP1	Rasgrp1			8567	-0.104	0.0904	No
65	NFKBIB	Nfkbib			8596	-0.107	0.0904	No
66	PAK2	Pak2			8614	-0.109	0.0911	No
67	PIK3R5	Pik3r5			9023	-0.172	0.0675	No
68	MAPK13	Mapk13			9159	-0.190	0.0619	No
69	KRAS	Kras			9184	-0.193	0.0636	No
70	PIK3CB	Pik3cb			9473	-0.238	0.0489	No
71	MAPK1	Mapk1			9523	-0.246	0.0498	No
72	PAK4	Pak4			9576	-0.254	0.0507	No
73	FYN	Fyn			10341	-0.379	0.0074	No
74	MAPK11	Mapk11			10363	-0.382	0.0124	No
75	GRB2	Grb2			10985	-0.438	-0.0205	No
76	NFKB1	Nfkb1			11113	-0.463	-0.0210	No
77	RAF1	Raf1			11324	-0.492	-0.0265	No
78	VAV2	Vav2			11548	-0.525	-0.0322	No
79	GRAP2	Grap2			11580	-0.532	-0.0253	No
80	PTPRC	Ptprc			11647	-0.543	-0.0206	No
81	PIK3R1	Pik3r1			11750	-0.565	-0.0178	No
82	ZAP70	Zap70			11801	-0.573	-0.0115	No
83	MAPK9	Mapk9			11878	-0.588	-0.0067	No
84	MAPK14	Mapk14			12063	-0.629	-0.0081	No
85	PAK1	Pak1			12137	-0.646	-0.0021	No
86	LCK	Lck			12197	-0.660	0.0050	No
87	HRAS	Hras			12226	-0.666	0.0143	No
88	PAK3	Pak3			12360	-0.697	0.0173	No
89	IL5	Il5			13032	-0.850	-0.0121	No
90	PAK6	Pak6			14067	-1.241	-0.0584	No
91	MAP3K14	Map3k14			14142	-1.290	-0.0418	No
92	PPP3CC	Ppp3cc			14434	-1.476	-0.0361	No
93	JUN	Jun			14761	-1.775	-0.0277	No
94	PTPN6	Ptpn6			15077	-2.302	-0.0098	No
95	NFATC2	Nfatc2			15091	-2.333	0.0281	No

Fig 2: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY