Details for gene set KEGG_VEGF_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NG_versus_LG.phenotype.cls#NG_versus_LG_repos
Phenotype	phenotype.cls#NG_versus_LG_repos
Upregulated in class	NG
GeneSet	KEGG_VEGF_SIGNALING_PATHWAY
Enrichment Score (ES)	0.3414762
Normalized Enrichment Score (NES)	1.3251008
Nominal p-value	0.03986711
FDR q-value	0.30607215
FWER p-Value	0.992

Fig 1: Enrichment plot: KEGG_VEGF_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	KDR	Kdr			4	4.063	0.0995	Yes
2	HSPB1	Hspb1			20	3.266	0.1788	Yes
3	NFAT5	Nfat5			234	2.145	0.2177	Yes
4	VEGFA	Vegfa			412	1.773	0.2498	Yes
5	PLA2G3	Pla2g3			527	1.644	0.2828	Yes
6	CASP9	Casp9			587	1.576	0.3176	Yes
7	SPHK1	Sphk1			1001	1.267	0.3220	Yes
8	PLCG2	Plcg2			1349	1.099	0.3266	Yes
9	PLCG1	Plcg1			1638	0.987	0.3322	Yes
10	CHP1	Chp1			2165	0.825	0.3184	Yes
11	MAPKAPK3	Mapkapk3			2543	0.725	0.3118	Yes
12	PIK3CA	Pik3ca			2701	0.689	0.3186	Yes
13	NRAS	Nras			3047	0.622	0.3116	Yes
14	PTGS2	Ptgs2			3102	0.610	0.3230	Yes
15	MAPK3	Mapk3			3365	0.559	0.3198	Yes
16	PXN	Pxn			3438	0.546	0.3286	Yes
17	MAP2K1	Map2k1			3446	0.545	0.3415	Yes
18	MAPKAPK2	Mapkapk2			3914	0.484	0.3231	No
19	PLA2G4A	Pla2g4a			4759	0.366	0.2775	No
20	SPHK2	Sphk2			4782	0.361	0.2850	No
21	NFATC4	Nfatc4			5131	0.307	0.2700	No
22	PPP3CA	Ppp3ca			5291	0.283	0.2667	No
23	SRC	Src			5536	0.248	0.2570	No
24	PIK3CG	Pik3cg			5708	0.224	0.2514	No
25	PLA2G12B	Pla2g12b			5923	0.189	0.2422	No
26	PPP3CB	Ppp3cb			6122	0.159	0.2333	No
27	PIK3CD	Pik3cd			6360	0.128	0.2211	No
28	PLA2G10	Pla2g10			6585	0.093	0.2089	No
29	PLA2G6	Pla2g6			6809	0.067	0.1961	No
30	AKT1	Akt1			6815	0.066	0.1974	No
31	MAPK12	Mapk12			6820	0.065	0.1988	No
32	AKT2	Akt2			6903	0.054	0.1948	No
33	NFATC3	Nfatc3			6904	0.054	0.1961	No
34	NFATC1	Nfatc1			6933	0.051	0.1956	No
35	PLA2G12A	Pla2g12a			6934	0.051	0.1968	No
36	SH2D2A	Sh2d2a			7344	0.000	0.1703	No
37	CHP2	Chp2			7370	0.000	0.1687	No
38	PPP3R2	Ppp3r2			7574	0.000	0.1556	No
39	PLA2G5	Pla2g5			7784	0.000	0.1421	No
40	AKT3	Akt3			8066	-0.032	0.1247	No
41	PRKCA	Prkca			8287	-0.065	0.1121	No
42	CDC42	Cdc42			8435	-0.086	0.1047	No
43	PLA2G1B	Pla2g1b			8850	-0.143	0.0814	No
44	PIK3R5	Pik3r5			9023	-0.172	0.0745	No
45	PTK2	Ptk2			9121	-0.184	0.0727	No
46	MAPK13	Mapk13			9159	-0.190	0.0750	No
47	KRAS	Kras			9184	-0.193	0.0782	No
48	PIK3CB	Pik3cb			9473	-0.238	0.0654	No
49	MAPK1	Mapk1			9523	-0.246	0.0683	No
50	RAC1	Rac1			9562	-0.252	0.0721	No
51	BAD	Bad			9962	-0.319	0.0541	No
52	PLA2G2E	Pla2g2e			10333	-0.376	0.0394	No
53	MAPK11	Mapk11			10363	-0.382	0.0469	No
54	PLA2G2D	Pla2g2d			10882	-0.432	0.0240	No
55	RAC3	Rac3			11001	-0.441	0.0272	No
56	PLA2G4E	Pla2g4e			11150	-0.470	0.0292	No
57	RAF1	Raf1			11324	-0.492	0.0301	No
58	PIK3R1	Pik3r1			11750	-0.565	0.0165	No
59	PRKCG	Prkcg			12036	-0.622	0.0133	No
60	MAPK14	Mapk14			12063	-0.629	0.0271	No
61	HRAS	Hras			12226	-0.666	0.0329	No
62	RAC2	Rac2			12774	-0.795	0.0171	No
63	NOS3	Nos3			12988	-0.841	0.0240	No
64	PPP3CC	Ppp3cc			14434	-1.476	-0.0332	No
65	PRKCB	Prkcb			14851	-1.889	-0.0138	No
66	NFATC2	Nfatc2			15091	-2.333	0.0281	No

Fig 2: KEGG_VEGF_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_VEGF_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_VEGF_SIGNALING_PATHWAY