Details for gene set KEGG_ACUTE_MYELOID_LEUKEMIA[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	NGP
GeneSet	KEGG_ACUTE_MYELOID_LEUKEMIA
Enrichment Score (ES)	0.32256338
Normalized Enrichment Score (NES)	1.3930627
Nominal p-value	0.0
FDR q-value	0.2735
FWER p-Value	0.856

Fig 1: Enrichment plot: KEGG_ACUTE_MYELOID_LEUKEMIA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FLT3	Flt3			17	4.618	0.0898	Yes
2	LEF1	Lef1			52	4.231	0.1709	Yes
3	PIM1	Pim1			265	3.373	0.2236	Yes
4	IKBKG	Ikbkg			706	2.530	0.2450	Yes
5	RUNX1T1	Runx1t1			1574	1.663	0.2216	Yes
6	PIK3CD	Pik3cd			1661	1.603	0.2476	Yes
7	TCF7L1	Tcf7l1			1686	1.589	0.2774	Yes
8	NRAS	Nras			1999	1.405	0.2849	Yes
9	SPI1	Spi1			2018	1.398	0.3112	Yes
10	JUP	Jup			2238	1.295	0.3226	Yes
11	STAT3	Stat3			2733	1.085	0.3120	No
12	IKBKB	Ikbkb			3470	0.850	0.2811	No
13	PIK3CG	Pik3cg			3524	0.831	0.2941	No
14	EIF4EBP1	Eif4ebp1			3742	0.777	0.2954	No
15	MAPK3	Mapk3			4012	0.720	0.2922	No
16	ZBTB16	Zbtb16			4070	0.708	0.3024	No
17	STAT5A	Stat5a			4244	0.660	0.3042	No
18	SOS2	Sos2			4544	0.582	0.2963	No
19	ARAF	Araf			4642	0.557	0.3010	No
20	RUNX1	Runx1			4989	0.482	0.2882	No
21	RARA	Rara			5279	0.432	0.2780	No
22	PIM2	Pim2			5368	0.425	0.2807	No
23	BRAF	Braf			5445	0.408	0.2838	No
24	CEBPA	Cebpa			5466	0.405	0.2904	No
25	CHUK	Chuk			5683	0.379	0.2839	No
26	PPARD	Ppard			5691	0.378	0.2909	No
27	STAT5B	Stat5b			6014	0.334	0.2767	No
28	RELA	Rela			6511	0.233	0.2492	No
29	AKT2	Akt2			6853	0.164	0.2304	No
30	AKT1	Akt1			7042	0.129	0.2208	No
31	PIK3CA	Pik3ca			7585	0.030	0.1864	No
32	SOS1	Sos1			8166	-0.030	0.1495	No
33	RPS6KB2	Rps6kb2			8290	-0.055	0.1426	No
34	BAD	Bad			8802	-0.146	0.1125	No
35	PIK3R5	Pik3r5			8900	-0.160	0.1094	No
36	MTOR	Mtor			9221	-0.219	0.0930	No
37	TCF7L2	Tcf7l2			9232	-0.220	0.0967	No
38	HRAS	Hras			9287	-0.231	0.0977	No
39	MAP2K1	Map2k1			9298	-0.232	0.1017	No
40	CCNA1	Ccna1			10123	-0.394	0.0561	No
41	MAPK1	Mapk1			10768	-0.489	0.0242	No
42	KRAS	Kras			11151	-0.567	0.0106	No
43	GRB2	Grb2			11322	-0.609	0.0116	No
44	KIT	Kit			11441	-0.637	0.0165	No
45	RAF1	Raf1			11555	-0.662	0.0223	No
46	TCF7	Tcf7			11581	-0.668	0.0338	No
47	AKT3	Akt3			11977	-0.777	0.0235	No
48	MYC	Myc			13033	-1.135	-0.0223	No
49	PIK3CB	Pik3cb			13719	-1.479	-0.0375	No
50	PIK3R1	Pik3r1			13721	-1.480	-0.0084	No
51	PML	Pml			13930	-1.638	0.0104	No
52	NFKB1	Nfkb1			14275	-1.949	0.0265	No
53	CCND1	Ccnd1			14834	-2.752	0.0447	No

Fig 2: KEGG_ACUTE_MYELOID_LEUKEMIA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_ACUTE_MYELOID_LEUKEMIA: Random ES distribution   
Gene set null distribution of ES for KEGG_ACUTE_MYELOID_LEUKEMIA