Details for gene set KEGG_AXON_GUIDANCE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	NGP
GeneSet	KEGG_AXON_GUIDANCE
Enrichment Score (ES)	0.35204583
Normalized Enrichment Score (NES)	1.6010805
Nominal p-value	0.0
FDR q-value	0.29111183
FWER p-Value	0.376

Fig 1: Enrichment plot: KEGG_AXON_GUIDANCE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SRGAP1	Srgap1			15	4.654	0.0281	Yes
2	PLXNC1	Plxnc1			65	4.169	0.0509	Yes
3	SEMA3E	Sema3e			134	3.830	0.0704	Yes
4	CXCR4	Cxcr4			155	3.749	0.0924	Yes
5	DPYSL5	Dpysl5			167	3.712	0.1149	Yes
6	ABLIM3	Ablim3			183	3.625	0.1365	Yes
7	EPHA4	Epha4			200	3.559	0.1577	Yes
8	EPHB2	Ephb2			260	3.388	0.1750	Yes
9	SEMA6C	Sema6c			294	3.306	0.1935	Yes
10	EFNA3	Efna3			357	3.116	0.2089	Yes
11	SEMA3C	Sema3c			457	2.928	0.2207	Yes
12	EPHB4	Ephb4			659	2.607	0.2239	Yes
13	GNAI1	Gnai1			694	2.552	0.2376	Yes
14	ABLIM2	Ablim2			844	2.370	0.2427	Yes
15	SLIT1	Slit1			887	2.326	0.2545	Yes
16	ROBO1	Robo1			912	2.301	0.2673	Yes
17	PLXNB1	Plxnb1			960	2.245	0.2783	Yes
18	ROBO2	Robo2			1025	2.169	0.2876	Yes
19	L1CAM	L1cam			1027	2.168	0.3011	Yes
20	EPHA7	Epha7			1201	1.986	0.3022	Yes
21	EFNA4	Efna4			1208	1.977	0.3142	Yes
22	UNC5A	Unc5a			1362	1.835	0.3157	Yes
23	RHOD	Rhod			1581	1.657	0.3119	Yes
24	SEMA4D	Sema4d			1641	1.615	0.3181	Yes
25	NCK2	Nck2			1656	1.606	0.3272	Yes
26	NTN4	Ntn4			1778	1.531	0.3289	Yes
27	EFNB3	Efnb3			1897	1.464	0.3304	Yes
28	SEMA6A	Sema6a			1962	1.432	0.3352	Yes
29	NRAS	Nras			1999	1.405	0.3416	Yes
30	SEMA6D	Sema6d			2078	1.370	0.3451	Yes
31	ROBO3	Robo3			2102	1.359	0.3520	Yes
32	PLXNB3	Plxnb3			2369	1.239	0.3425	No
33	SLIT2	Slit2			2554	1.152	0.3377	No
34	NFAT5	Nfat5			2597	1.137	0.3421	No
35	SEMA5B	Sema5b			2718	1.091	0.3411	No
36	LRRC4C	Lrrc4c			2737	1.083	0.3467	No
37	PLXNA1	Plxna1			3373	0.868	0.3109	No
38	GSK3B	Gsk3b			3418	0.860	0.3134	No
39	PLXNA2	Plxna2			3510	0.836	0.3127	No
40	FES	Fes			3865	0.745	0.2943	No
41	CXCL12	Cxcl12			4011	0.720	0.2894	No
42	MAPK3	Mapk3			4012	0.720	0.2939	No
43	PAK5	Pak7			4180	0.678	0.2873	No
44	CDK5	Cdk5			4388	0.624	0.2777	No
45	DPYSL2	Dpysl2			4408	0.618	0.2804	No
46	EPHA2	Epha2			4545	0.582	0.2752	No
47	SRGAP3	Srgap3			4553	0.581	0.2783	No
48	PLXNA3	Plxna3			4749	0.530	0.2690	No
49	CFL2	Cfl2			4849	0.507	0.2657	No
50	CHP1	Chp1			5147	0.454	0.2492	No
51	EFNA2	Efna2			5178	0.447	0.2501	No
52	FYN	Fyn			5264	0.436	0.2473	No
53	SEMA4C	Sema4c			5268	0.435	0.2498	No
54	SEMA3B	Sema3b			5384	0.421	0.2450	No
55	PPP3R2	Ppp3r2			5524	0.401	0.2384	No
56	ARHGEF12	Arhgef12			5723	0.368	0.2279	No
57	UNC5D	Unc5d			5860	0.356	0.2213	No
58	SEMA3G	Sema3g			6057	0.326	0.2106	No
59	EFNB1	Efnb1			6531	0.229	0.1813	No
60	PLXNB2	Plxnb2			6720	0.195	0.1703	No
61	LIMK1	Limk1			6779	0.181	0.1676	No
62	ROCK1	Rock1			7085	0.119	0.1486	No
63	EPHB1	Ephb1			7394	0.062	0.1290	No
64	EPHA6	Epha6			7615	0.025	0.1148	No
65	SEMA4B	Sema4b			7676	0.012	0.1110	No
66	NFATC1	Nfatc1			7704	0.008	0.1093	No
67	EPHA8	Epha8			8071	-0.011	0.0856	No
68	LIMK2	Limk2			8144	-0.026	0.0811	No
69	CHP2	Chp2			8436	-0.082	0.0627	No
70	PAK6	Pak6			8612	-0.113	0.0521	No
71	SEMA4G	Sema4g			8738	-0.135	0.0448	No
72	ABL1	Abl1			8739	-0.135	0.0456	No
73	EFNA1	Efna1			8793	-0.142	0.0431	No
74	NFATC3	Nfatc3			8813	-0.148	0.0428	No
75	RAC3	Rac3			9015	-0.180	0.0308	No
76	SEMA4A	Sema4a			9166	-0.208	0.0224	No
77	RHOA	Rhoa			9229	-0.220	0.0197	No
78	RAC2	Rac2			9271	-0.227	0.0185	No
79	HRAS	Hras			9287	-0.231	0.0189	No
80	SEMA3F	Sema3f			9408	-0.254	0.0127	No
81	PAK4	Pak4			9515	-0.272	0.0076	No
82	SEMA3D	Sema3d			9516	-0.272	0.0092	No
83	NCK1	Nck1			9609	-0.291	0.0051	No
84	CFL1	Cfl1			9812	-0.332	-0.0060	No
85	PAK3	Pak3			9856	-0.340	-0.0066	No
86	NFATC4	Nfatc4			10107	-0.391	-0.0204	No
87	PPP3CA	Ppp3ca			10109	-0.391	-0.0181	No
88	ITGB1	Itgb1			10224	-0.414	-0.0229	No
89	ROCK2	Rock2			10537	-0.442	-0.0404	No
90	PPP3CB	Ppp3cb			10538	-0.443	-0.0376	No
91	PAK2	Pak2			10634	-0.463	-0.0409	No
92	MAPK1	Mapk1			10768	-0.489	-0.0465	No
93	UNC5B	Unc5b			10796	-0.495	-0.0451	No
94	DCC	Dcc			10984	-0.530	-0.0540	No
95	CDC42	Cdc42			11074	-0.550	-0.0563	No
96	KRAS	Kras			11151	-0.567	-0.0577	No
97	SEMA4F	Sema4f			11379	-0.624	-0.0686	No
98	GNAI2	Gnai2			11388	-0.627	-0.0652	No
99	EFNA5	Efna5			11405	-0.629	-0.0623	No
100	PTK2	Ptk2			11527	-0.655	-0.0661	No
101	SEMA6B	Sema6b			11662	-0.688	-0.0705	No
102	GNAI3	Gnai3			11788	-0.724	-0.0741	No
103	EPHB3	Ephb3			12449	-0.918	-0.1112	No
104	RAC1	Rac1			12614	-0.976	-0.1158	No
105	RASA1	Rasa1			12671	-0.994	-0.1132	No
106	RND1	Rnd1			12719	-1.014	-0.1100	No
107	PAK1	Pak1			13152	-1.182	-0.1306	No
108	RGS3	Rgs3			13198	-1.206	-0.1260	No
109	NTNG1	Ntng1			13266	-1.236	-0.1227	No
110	EPHB6	Ephb6			13310	-1.254	-0.1176	No
111	PPP3CC	Ppp3cc			13434	-1.328	-0.1173	No
112	MET	Met			13710	-1.474	-0.1260	No
113	NTN1	Ntn1			13775	-1.524	-0.1207	No
114	ABLIM1	Ablim1			14101	-1.773	-0.1307	No
115	NRP1	Nrp1			14157	-1.822	-0.1229	No
116	EFNB2	Efnb2			14306	-1.985	-0.1202	No
117	NTN3	Ntn3			14500	-2.220	-0.1188	No
118	SEMA5A	Sema5a			14555	-2.304	-0.1080	No
119	UNC5C	Unc5c			14574	-2.329	-0.0946	No
120	NGEF	Ngef			14685	-2.507	-0.0861	No
121	SLIT3	Slit3			14732	-2.577	-0.0730	No
122	EPHA1	Epha1			14914	-2.904	-0.0667	No
123	SEMA7A	Sema7a			14978	-3.070	-0.0516	No
124	EPHA3	Epha3			14987	-3.090	-0.0329	No
125	SEMA3A	Sema3a			15141	-3.539	-0.0207	No
126	NFATC2	Nfatc2			15146	-3.562	0.0012	No
127	EPHA5	Epha5			15210	-3.737	0.0205	No

Fig 2: KEGG_AXON_GUIDANCE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_AXON_GUIDANCE: Random ES distribution   
Gene set null distribution of ES for KEGG_AXON_GUIDANCE