Details for gene set KEGG_CHEMOKINE_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_CHEMOKINE_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.32680577
Normalized Enrichment Score (NES)	-1.6442994
Nominal p-value	0.0
FDR q-value	0.085574515
FWER p-Value	0.256

Fig 1: Enrichment plot: KEGG_CHEMOKINE_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GNG4	Gng4			94	3.983	0.0169	No
2	ITK	Itk			129	3.848	0.0370	No
3	CXCR4	Cxcr4			155	3.749	0.0570	No
4	RASGRP2	Rasgrp2			296	3.301	0.0670	No
5	ADCY1	Adcy1			388	3.055	0.0788	No
6	ELMO1	Elmo1			644	2.632	0.0774	No
7	GNAI1	Gnai1			694	2.552	0.0890	No
8	IKBKG	Ikbkg			706	2.530	0.1029	No
9	PRKCZ	Prkcz			807	2.415	0.1104	No
10	CCR7	Ccr7			1181	2.008	0.0978	No
11	LYN	Lyn			1345	1.850	0.0979	No
12	STAT2	Stat2			1360	1.835	0.1076	No
13	GRK4	Grk4			1405	1.790	0.1151	No
14	PRKCD	Prkcd			1494	1.727	0.1193	No
15	CXCR2	Cxcr2			1558	1.675	0.1249	No
16	PLCB4	Plcb4			1583	1.655	0.1329	No
17	PIK3CD	Pik3cd			1661	1.603	0.1372	No
18	NCF1	Ncf1			1789	1.525	0.1378	No
19	GNG8	Gng8			1821	1.510	0.1445	No
20	NRAS	Nras			1999	1.405	0.1411	No
21	GNB3	Gnb3			2154	1.335	0.1388	No
22	CX3CR1	Cx3cr1			2232	1.298	0.1413	No
23	GNG3	Gng3			2501	1.178	0.1307	No
24	STAT3	Stat3			2733	1.085	0.1219	No
25	CCR4	Ccr4			3176	0.926	0.0986	No
26	PREX1	Prex1			3241	0.906	0.0996	No
27	BCAR1	Bcar1			3392	0.865	0.0949	No
28	GSK3B	Gsk3b			3418	0.860	0.0982	No
29	ADCY5	Adcy5			3459	0.852	0.1006	No
30	IKBKB	Ikbkb			3470	0.850	0.1048	No
31	PIK3CG	Pik3cg			3524	0.831	0.1062	No
32	SHC1	Shc1			3603	0.815	0.1058	No
33	WASL	Wasl			3722	0.784	0.1027	No
34	CXCL12	Cxcl12			4011	0.720	0.0881	No
35	MAPK3	Mapk3			4012	0.720	0.0923	No
36	PLCB2	Plcb2			4543	0.582	0.0612	No
37	SOS2	Sos2			4544	0.582	0.0646	No
38	ADCY6	Adcy6			4574	0.576	0.0660	No
39	PARD3	Pard3			4682	0.545	0.0622	No
40	CXCR5	Cxcr5			4705	0.541	0.0639	No
41	GNG5	Gm4356			5051	0.474	0.0442	No
42	BRAF	Braf			5445	0.408	0.0210	No
43	CCR2	Ccr2			5563	0.401	0.0157	No
44	CHUK	Chuk			5683	0.379	0.0102	No
45	GRK3	Grk3			5772	0.359	0.0065	No
46	VAV1	Vav1			5811	0.356	0.0061	No
47	CXCL16	Cxcl16			6008	0.335	-0.0047	No
48	STAT5B	Stat5b			6014	0.334	-0.0031	No
49	VAV2	Vav2			6085	0.320	-0.0058	No
50	GNGT2	Gngt2			6402	0.256	-0.0249	No
51	CCL28	Ccl28			6453	0.246	-0.0267	No
52	ADCY3	Adcy3			6455	0.245	-0.0253	No
53	STAT1	Stat1			6479	0.238	-0.0255	No
54	ADCY9	Adcy9			6506	0.234	-0.0258	No
55	RELA	Rela			6511	0.233	-0.0247	No
56	CSK	Csk			6540	0.226	-0.0252	No
57	GNG12	Gng12			6617	0.212	-0.0289	No
58	NFKBIB	Nfkbib			6721	0.193	-0.0345	No
59	AKT2	Akt2			6853	0.164	-0.0421	No
60	NFKBIA	Nfkbia			6940	0.148	-0.0468	No
61	GNB2	Gnb2			7038	0.129	-0.0524	No
62	AKT1	Akt1			7042	0.129	-0.0518	No
63	ROCK1	Rock1			7085	0.119	-0.0539	No
64	CRK	Crk			7127	0.113	-0.0559	No
65	ADCY2	Adcy2			7183	0.102	-0.0589	No
66	GNB1	Gnb1			7377	0.064	-0.0711	No
67	CCR1	Ccr1			7400	0.061	-0.0721	No
68	PXN	Pxn			7416	0.059	-0.0728	No
69	DOCK2	Dock2			7509	0.043	-0.0785	No
70	PIK3CA	Pik3ca			7585	0.030	-0.0832	No
71	WAS	Was			7646	0.019	-0.0870	No
72	CCL27	Ccl27a			7872	0.000	-0.1016	No
73	CCR6	Ccr6			8010	0.000	-0.1105	No
74	CCR3	Ccr3			8011	0.000	-0.1105	No
75	SOS1	Sos1			8166	-0.030	-0.1204	No
76	GRK2	Grk2			8351	-0.066	-0.1320	No
77	VAV3	Vav3			8467	-0.087	-0.1389	No
78	GNB5	Gnb5			8495	-0.093	-0.1402	No
79	SHC3	Shc3			8552	-0.102	-0.1432	No
80	GRK5	Grk5			8662	-0.122	-0.1496	No
81	ARRB2	Arrb2			8673	-0.123	-0.1495	No
82	CCL22	Ccl22			8700	-0.128	-0.1505	No
83	TIAM1	Tiam1			8817	-0.149	-0.1572	No
84	PIK3R5	Pik3r5			8900	-0.160	-0.1616	No
85	GSK3A	Gsk3a			8919	-0.165	-0.1618	No
86	PLCB3	Plcb3			9108	-0.196	-0.1729	No
87	RHOA	Rhoa			9229	-0.220	-0.1794	No
88	RAC2	Rac2			9271	-0.227	-0.1808	No
89	HRAS	Hras			9287	-0.231	-0.1804	No
90	MAP2K1	Map2k1			9298	-0.232	-0.1797	No
91	RAP1B	Rap1b			9457	-0.264	-0.1885	No
92	CRKL	Crkl			9708	-0.310	-0.2029	No
93	JAK2	Jak2			9992	-0.367	-0.2192	No
94	GNG13	Gng13			10057	-0.381	-0.2212	No
95	CXCL9	Cxcl9			10485	-0.440	-0.2464	No
96	ROCK2	Rock2			10537	-0.442	-0.2471	No
97	JAK3	Jak3			10604	-0.458	-0.2488	No
98	GNG10	Gng10			10674	-0.473	-0.2505	No
99	MAPK1	Mapk1			10768	-0.489	-0.2538	No
100	FOXO3	Foxo3			10853	-0.502	-0.2563	No
101	CDC42	Cdc42			11074	-0.550	-0.2674	No
102	CCL20	Ccl20			11149	-0.567	-0.2690	No
103	KRAS	Kras			11151	-0.567	-0.2658	No
104	TIAM2	Tiam2			11232	-0.586	-0.2676	No
105	GRB2	Grb2			11322	-0.609	-0.2698	No
106	GNAI2	Gnai2			11388	-0.627	-0.2704	No
107	PTK2	Ptk2			11527	-0.655	-0.2756	No
108	RAF1	Raf1			11555	-0.662	-0.2736	No
109	CCR9	Ccr9			11560	-0.662	-0.2700	No
110	GNAI3	Gnai3			11788	-0.724	-0.2806	No
111	GRK1	Grk1			11818	-0.734	-0.2782	No
112	RAP1A	Rap1a			11967	-0.775	-0.2834	No
113	FGR	Fgr			11970	-0.776	-0.2790	No
114	AKT3	Akt3			11977	-0.777	-0.2749	No
115	CCR10	Ccr10			12041	-0.798	-0.2744	No
116	ADCY4	Adcy4			12086	-0.808	-0.2726	No
117	PPBP	Ppbp			12400	-0.900	-0.2877	No
118	GNB4	Gnb4			12486	-0.933	-0.2878	No
119	GRK6	Grk6			12505	-0.941	-0.2836	No
120	PRKACB	Prkacb			12518	-0.946	-0.2789	No
121	RAC1	Rac1			12614	-0.976	-0.2794	No
122	GNG7	Gng7			12942	-1.098	-0.2943	No
123	PAK1	Pak1			13152	-1.182	-0.3011	No
124	GNG11	Gng11			13420	-1.320	-0.3108	No
125	CXCL6	Cxcl5			13667	-1.455	-0.3184	Yes
126	PIK3CB	Pik3cb			13719	-1.479	-0.3132	Yes
127	PIK3R1	Pik3r1			13721	-1.480	-0.3047	Yes
128	PRKACA	Prkaca			13821	-1.556	-0.3021	Yes
129	ARRB1	Arrb1			14002	-1.696	-0.3040	Yes
130	NFKB1	Nfkb1			14275	-1.949	-0.3104	Yes
131	SHC4	Shc4			14330	-2.013	-0.3023	Yes
132	PTK2B	Ptk2b			14456	-2.167	-0.2979	Yes
133	CCL5	Ccl5			14720	-2.558	-0.3002	Yes
134	CCL8	Ccl12			14739	-2.586	-0.2864	Yes
135	CXCL11	Cxcl11			14829	-2.741	-0.2763	Yes
136	ADCY7	Adcy7			14846	-2.774	-0.2613	Yes
137	CX3CL1	Cx3cl1			14968	-3.055	-0.2515	Yes
138	ADCY8	Adcy8			14970	-3.056	-0.2339	Yes
139	GNG2	Gng2			15005	-3.135	-0.2180	Yes
140	CXCL10	Cxcl10			15059	-3.303	-0.2023	Yes
141	CXCR6	Cxcr6			15111	-3.464	-0.1856	Yes
142	CCL2	Ccl2			15151	-3.576	-0.1674	Yes
143	CCL17	Ccl17			15208	-3.733	-0.1495	Yes
144	HCK	Hck			15221	-3.789	-0.1283	Yes
145	PLCB1	Plcb1			15241	-3.854	-0.1073	Yes
146	CCL11	Ccl11			15265	-3.932	-0.0860	Yes
147	XCR1	Xcr1			15305	-4.062	-0.0650	Yes
148	CCL7	Ccl7			15346	-4.215	-0.0433	Yes
149	CXCL14	Cxcl14			15467	-4.630	-0.0243	Yes
150	PRKCB	Prkcb			15515	-4.838	0.0007	Yes

Fig 2: KEGG_CHEMOKINE_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_CHEMOKINE_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_CHEMOKINE_SIGNALING_PATHWAY