Details for gene set KEGG_ERBB_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_ERBB_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.33062512
Normalized Enrichment Score (NES)	-1.6448158
Nominal p-value	0.0
FDR q-value	0.081694156
FWER p-Value	0.211

Fig 1: Enrichment plot: KEGG_ERBB_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PLCG2	Plcg2			735	2.492	-0.0158	No
2	NRG4	Nrg4			843	2.371	0.0075	No
3	TGFA	Tgfa			1450	1.754	-0.0094	No
4	PLCG1	Plcg1			1648	1.613	-0.0016	No
5	NCK2	Nck2			1656	1.606	0.0184	No
6	PIK3CD	Pik3cd			1661	1.603	0.0386	No
7	NRAS	Nras			1999	1.405	0.0347	No
8	PRKCG	Prkcg			2224	1.299	0.0367	No
9	CBLB	Cblb			2551	1.153	0.0303	No
10	ELK1	Elk1			2849	1.035	0.0243	No
11	ERBB2	Erbb2			3125	0.943	0.0185	No
12	GSK3B	Gsk3b			3418	0.860	0.0105	No
13	PIK3CG	Pik3cg			3524	0.831	0.0143	No
14	SHC1	Shc1			3603	0.815	0.0197	No
15	EIF4EBP1	Eif4ebp1			3742	0.777	0.0206	No
16	GAB1	Gab1			3808	0.759	0.0261	No
17	MAPK3	Mapk3			4012	0.720	0.0221	No
18	PAK5	Pak7			4180	0.678	0.0200	No
19	STAT5A	Stat5a			4244	0.660	0.0243	No
20	MAP2K7	Map2k7			4263	0.656	0.0315	No
21	CDKN1A	Cdkn1a			4516	0.587	0.0227	No
22	SOS2	Sos2			4544	0.582	0.0283	No
23	ARAF	Araf			4642	0.557	0.0292	No
24	MAPK8	Mapk8			4803	0.518	0.0254	No
25	CBL	Cbl			4818	0.516	0.0311	No
26	MAPK10	Mapk10			5168	0.449	0.0142	No
27	BRAF	Braf			5445	0.408	0.0015	No
28	ERBB4	Erbb4			5821	0.356	-0.0182	No
29	NRG1	Nrg1			5992	0.338	-0.0249	No
30	STAT5B	Stat5b			6014	0.334	-0.0220	No
31	AKT2	Akt2			6853	0.164	-0.0742	No
32	AKT1	Akt1			7042	0.129	-0.0847	No
33	CRK	Crk			7127	0.113	-0.0887	No
34	PIK3CA	Pik3ca			7585	0.030	-0.1179	No
35	SOS1	Sos1			8166	-0.030	-0.1551	No
36	RPS6KB2	Rps6kb2			8290	-0.055	-0.1623	No
37	SHC3	Shc3			8552	-0.102	-0.1779	No
38	PAK6	Pak6			8612	-0.113	-0.1803	No
39	MAP2K4	Map2k4			8722	-0.131	-0.1857	No
40	ABL1	Abl1			8739	-0.135	-0.1850	No
41	BAD	Bad			8802	-0.146	-0.1871	No
42	SRC	Src			8880	-0.156	-0.1901	No
43	PIK3R5	Pik3r5			8900	-0.160	-0.1893	No
44	MTOR	Mtor			9221	-0.219	-0.2073	No
45	HRAS	Hras			9287	-0.231	-0.2085	No
46	MAP2K1	Map2k1			9298	-0.232	-0.2062	No
47	CBLC	Cblc			9514	-0.271	-0.2167	No
48	PAK4	Pak4			9515	-0.272	-0.2132	No
49	NCK1	Nck1			9609	-0.291	-0.2155	No
50	CRKL	Crkl			9708	-0.310	-0.2179	No
51	PAK3	Pak3			9856	-0.340	-0.2231	No
52	ABL2	Abl2			10431	-0.432	-0.2548	No
53	MAPK9	Mapk9			10579	-0.451	-0.2585	No
54	PAK2	Pak2			10634	-0.463	-0.2561	No
55	MAPK1	Mapk1			10768	-0.489	-0.2585	No
56	KRAS	Kras			11151	-0.567	-0.2760	No
57	GRB2	Grb2			11322	-0.609	-0.2792	No
58	PTK2	Ptk2			11527	-0.655	-0.2841	No
59	RAF1	Raf1			11555	-0.662	-0.2774	No
60	ERBB3	Erbb3			11789	-0.724	-0.2833	No
61	AKT3	Akt3			11977	-0.777	-0.2855	No
62	CDKN1B	Cdkn1b			12053	-0.801	-0.2801	No
63	NRG2	Nrg2			12699	-1.006	-0.3091	No
64	MYC	Myc			13033	-1.135	-0.3162	Yes
65	PAK1	Pak1			13152	-1.182	-0.3087	Yes
66	EGF	Egf			13161	-1.188	-0.2941	Yes
67	HBEGF	Hbegf			13569	-1.400	-0.3026	Yes
68	PIK3CB	Pik3cb			13719	-1.479	-0.2934	Yes
69	PIK3R1	Pik3r1			13721	-1.480	-0.2746	Yes
70	CAMK2G	Camk2g			13858	-1.580	-0.2633	Yes
71	PRKCA	Prkca			13942	-1.648	-0.2476	Yes
72	CAMK2A	Camk2a			14142	-1.811	-0.2375	Yes
73	SHC4	Shc4			14330	-2.013	-0.2239	Yes
74	EGFR	Egfr			14536	-2.270	-0.2082	Yes
75	JUN	Jun			14704	-2.538	-0.1867	Yes
76	AREG	Areg			14867	-2.807	-0.1614	Yes
77	EREG	Ereg			14981	-3.080	-0.1295	Yes
78	BTC	Btc			15172	-3.638	-0.0954	Yes
79	CAMK2B	Camk2b			15410	-4.432	-0.0543	Yes
80	PRKCB	Prkcb			15515	-4.838	0.0006	Yes

Fig 2: KEGG_ERBB_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_ERBB_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_ERBB_SIGNALING_PATHWAY