Details for gene set KEGG_MELANOMA[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_MELANOMA
Enrichment Score (ES)	-0.40398303
Normalized Enrichment Score (NES)	-1.5346752
Nominal p-value	0.0
FDR q-value	0.14105089
FWER p-Value	0.557

Fig 1: Enrichment plot: KEGG_MELANOMA   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FGF17	Fgf17			112	3.899	0.0519	No
2	FGF22	Fgf22			1195	1.992	0.0122	No
3	MDM2	Mdm2			1417	1.780	0.0249	No
4	PIK3CD	Pik3cd			1661	1.603	0.0335	No
5	NRAS	Nras			1999	1.405	0.0330	No
6	RB1	Rb1			2074	1.372	0.0491	No
7	PDGFB	Pdgfb			2294	1.269	0.0542	No
8	FGF5	Fgf5			2817	1.046	0.0363	No
9	FGF11	Fgf11			3502	0.839	0.0048	No
10	FGF18	Fgf18			3517	0.834	0.0165	No
11	PIK3CG	Pik3cg			3524	0.831	0.0287	No
12	FGF23	Fgf23			3960	0.732	0.0117	No
13	CDK4	Cdk4			4004	0.722	0.0199	No
14	MAPK3	Mapk3			4012	0.720	0.0304	No
15	CDKN1A	Cdkn1a			4516	0.587	0.0067	No
16	ARAF	Araf			4642	0.557	0.0071	No
17	BRAF	Braf			5445	0.408	-0.0386	No
18	IGF1R	Igf1r			6070	0.322	-0.0740	No
19	FGF2	Fgf2			6392	0.258	-0.0908	No
20	FGFR1	Fgfr1			6421	0.253	-0.0888	No
21	PTEN	Pten			6630	0.208	-0.0991	No
22	AKT2	Akt2			6853	0.164	-0.1110	No
23	AKT1	Akt1			7042	0.129	-0.1212	No
24	PIK3CA	Pik3ca			7585	0.030	-0.1558	No
25	FGF9	Fgf9			7721	0.004	-0.1644	No
26	FGF6	Fgf6			7965	0.000	-0.1801	No
27	FGF19	Fgf15			8061	-0.009	-0.1861	No
28	BAD	Bad			8802	-0.146	-0.2318	No
29	PIK3R5	Pik3r5			8900	-0.160	-0.2356	No
30	PDGFA	Pdgfa			9111	-0.196	-0.2462	No
31	FGF12	Fgf12			9237	-0.221	-0.2509	No
32	HRAS	Hras			9287	-0.231	-0.2506	No
33	MAP2K1	Map2k1			9298	-0.232	-0.2477	No
34	FGF10	Fgf10			9558	-0.280	-0.2602	No
35	E2F3	E2f3			9725	-0.313	-0.2662	No
36	PDGFC	Pdgfc			9842	-0.336	-0.2686	No
37	MAPK1	Mapk1			10768	-0.489	-0.3210	No
38	TP53	Trp53			10894	-0.512	-0.3213	No
39	KRAS	Kras			11151	-0.567	-0.3293	No
40	E2F1	E2f1			11427	-0.633	-0.3375	No
41	RAF1	Raf1			11555	-0.662	-0.3356	No
42	FGF21	Fgf21			11557	-0.662	-0.3257	No
43	AKT3	Akt3			11977	-0.777	-0.3410	No
44	CDK6	Cdk6			12347	-0.884	-0.3514	No
45	EGF	Egf			13161	-1.188	-0.3860	Yes
46	CDH1	Cdh1			13373	-1.294	-0.3800	Yes
47	FGF7	Fgf7			13408	-1.311	-0.3623	Yes
48	FGF14	Fgf14			13412	-1.313	-0.3426	Yes
49	MET	Met			13710	-1.474	-0.3394	Yes
50	PIK3CB	Pik3cb			13719	-1.479	-0.3175	Yes
51	PIK3R1	Pik3r1			13721	-1.480	-0.2951	Yes
52	E2F2	E2f2			14332	-2.016	-0.3039	Yes
53	PDGFRA	Pdgfra			14432	-2.130	-0.2780	Yes
54	PDGFD	Pdgfd			14454	-2.166	-0.2465	Yes
55	PDGFRB	Pdgfrb			14505	-2.226	-0.2160	Yes
56	EGFR	Egfr			14536	-2.270	-0.1835	Yes
57	MITF	Mitf			14595	-2.354	-0.1515	Yes
58	CCND1	Ccnd1			14834	-2.752	-0.1251	Yes
59	IGF1	Igf1			15091	-3.421	-0.0898	Yes
60	FGF1	Fgf1			15206	-3.722	-0.0407	Yes
61	HGF	Hgf			15293	-4.036	0.0150	Yes

Fig 2: KEGG_MELANOMA   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_MELANOMA: Random ES distribution   
Gene set null distribution of ES for KEGG_MELANOMA