Details for gene set KEGG_NEUROTROPHIN_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	NGP
GeneSet	KEGG_NEUROTROPHIN_SIGNALING_PATHWAY
Enrichment Score (ES)	0.21657312
Normalized Enrichment Score (NES)	1.3585553
Nominal p-value	0.0
FDR q-value	0.2935603
FWER p-Value	0.899

Fig 1: Enrichment plot: KEGG_NEUROTROPHIN_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IRS4	Irs4			235	3.470	0.0172	Yes
2	NGFR	Ngfr			248	3.430	0.0485	Yes
3	NTF4	Ntf5			406	3.015	0.0664	Yes
4	MAP3K5	Map3k5			565	2.774	0.0821	Yes
5	SORT1	Sort1			569	2.771	0.1078	Yes
6	PLCG2	Plcg2			735	2.492	0.1204	Yes
7	SH2B2	Sh2b2			959	2.247	0.1269	Yes
8	BAX	Bax			1205	1.979	0.1295	Yes
9	IRAK2	Irak2			1212	1.975	0.1476	Yes
10	PRKCD	Prkcd			1494	1.727	0.1455	Yes
11	MAPK7	Mapk7			1510	1.714	0.1605	Yes
12	MAPK12	Mapk12			1560	1.674	0.1730	Yes
13	PLCG1	Plcg1			1648	1.613	0.1824	Yes
14	PIK3CD	Pik3cd			1661	1.603	0.1966	Yes
15	TRAF6	Traf6			1712	1.577	0.2081	Yes
16	IRS1	Irs1			1873	1.480	0.2116	Yes
17	NRAS	Nras			1999	1.405	0.2166	Yes
18	PRDM4	Prdm4			2347	1.248	0.2057	No
19	MAPKAPK2	Mapkapk2			2848	1.035	0.1829	No
20	AC093012.1	Irak4			3336	0.879	0.1595	No
21	GSK3B	Gsk3b			3418	0.860	0.1623	No
22	IKBKB	Ikbkb			3470	0.850	0.1670	No
23	PIK3CG	Pik3cg			3524	0.831	0.1713	No
24	SHC1	Shc1			3603	0.815	0.1738	No
25	KIDINS220	Kidins220			3753	0.775	0.1714	No
26	GAB1	Gab1			3808	0.759	0.1750	No
27	BDNF	Bdnf			3836	0.752	0.1803	No
28	MAPK3	Mapk3			4012	0.720	0.1756	No
29	IRS2	Irs2			4023	0.718	0.1817	No
30	PSEN1	Psen1			4060	0.711	0.1860	No
31	MAP2K7	Map2k7			4263	0.656	0.1790	No
32	TP73	Trp73			4320	0.640	0.1814	No
33	MAPK11	Mapk11			4400	0.621	0.1820	No
34	SOS2	Sos2			4544	0.582	0.1782	No
35	NTRK2	Ntrk2			4751	0.529	0.1698	No
36	MAPK8	Mapk8			4803	0.518	0.1713	No
37	MAPK10	Mapk10			5168	0.449	0.1519	No
38	MAP3K1	Map3k1			5382	0.422	0.1420	No
39	NTRK3	Ntrk3			5403	0.417	0.1446	No
40	YWHAG	Ywhag			5416	0.413	0.1477	No
41	BRAF	Braf			5445	0.408	0.1497	No
42	BEX3	Bex3			5926	0.353	0.1218	No
43	RPS6KA6	Rps6ka6			6063	0.324	0.1160	No
44	RPS6KA5	Rps6ka5			6182	0.301	0.1112	No
45	ZNF274	Zfp110			6250	0.287	0.1095	No
46	RELA	Rela			6511	0.233	0.0948	No
47	CSK	Csk			6540	0.226	0.0951	No
48	NFKBIB	Nfkbib			6721	0.193	0.0852	No
49	AKT2	Akt2			6853	0.164	0.0783	No
50	CALML3	Calml3			6900	0.155	0.0767	No
51	NFKBIA	Nfkbia			6940	0.148	0.0756	No
52	AKT1	Akt1			7042	0.129	0.0702	No
53	PDPK1	Pdpk1			7121	0.114	0.0662	No
54	CRK	Crk			7127	0.113	0.0670	No
55	ATF4	Atf4			7177	0.103	0.0648	No
56	PIK3CA	Pik3ca			7585	0.030	0.0386	No
57	RIPK2	Ripk2			7729	0.003	0.0294	No
58	SOS1	Sos1			8166	-0.030	0.0014	No
59	SHC3	Shc3			8552	-0.102	-0.0227	No
60	ABL1	Abl1			8739	-0.135	-0.0335	No
61	BAD	Bad			8802	-0.146	-0.0362	No
62	PIK3R5	Pik3r5			8900	-0.160	-0.0409	No
63	YWHAB	Ywhab			8979	-0.173	-0.0444	No
64	ARHGDIA	Arhgdia			9074	-0.191	-0.0487	No
65	RHOA	Rhoa			9229	-0.220	-0.0567	No
66	HRAS	Hras			9287	-0.231	-0.0582	No
67	MAP2K1	Map2k1			9298	-0.232	-0.0567	No
68	RAPGEF1	Rapgef1			9338	-0.241	-0.0570	No
69	MAGED1	Maged1			9405	-0.254	-0.0589	No
70	RAP1B	Rap1b			9457	-0.264	-0.0597	No
71	NGF	Ngf			9492	-0.269	-0.0594	No
72	CRKL	Crkl			9708	-0.310	-0.0705	No
73	RPS6KA1	Rps6ka1			9858	-0.341	-0.0770	No
74	YWHAQ	Ywhaq			10023	-0.373	-0.0841	No
75	NTRK1	Ntrk1			10125	-0.394	-0.0870	No
76	NTF3	Ntf3			10168	-0.404	-0.0859	No
77	RPS6KA4	Rps6ka4			10438	-0.434	-0.0993	No
78	MAPK9	Mapk9			10579	-0.451	-0.1042	No
79	MAP2K5	Map2k5			10606	-0.458	-0.1016	No
80	MAPK1	Mapk1			10768	-0.489	-0.1075	No
81	FOXO3	Foxo3			10853	-0.502	-0.1083	No
82	TP53	Trp53			10894	-0.512	-0.1061	No
83	SH2B1	Sh2b1			10944	-0.521	-0.1044	No
84	CAMK4	Camk4			11062	-0.547	-0.1069	No
85	CDC42	Cdc42			11074	-0.550	-0.1024	No
86	FASLG	Fasl			11139	-0.565	-0.1013	No
87	KRAS	Kras			11151	-0.567	-0.0967	No
88	FRS2	Frs2			11207	-0.580	-0.0949	No
89	GRB2	Grb2			11322	-0.609	-0.0966	No
90	RAF1	Raf1			11555	-0.662	-0.1055	No
91	BCL2	Bcl2			11593	-0.671	-0.1016	No
92	YWHAH	Ywhah			11608	-0.674	-0.0962	No
93	RPS6KA2	Rps6ka2			11620	-0.677	-0.0906	No
94	IRAK1	Irak1			11647	-0.683	-0.0859	No
95	MAP3K3	Map3k3			11680	-0.693	-0.0815	No
96	MAPK14	Mapk14			11756	-0.714	-0.0797	No
97	RAP1A	Rap1a			11967	-0.775	-0.0861	No
98	AKT3	Akt3			11977	-0.777	-0.0794	No
99	YWHAZ	Ywhaz			11982	-0.778	-0.0724	No
100	RPS6KA3	Rps6ka3			12050	-0.800	-0.0692	No
101	YWHAE	Ywhae			12205	-0.844	-0.0714	No
102	SH2B3	Sh2b3			12242	-0.851	-0.0657	No
103	RAC1	Rac1			12614	-0.976	-0.0807	No
104	NFKBIE	Nfkbie			12634	-0.984	-0.0727	No
105	PTPN11	Ptpn11			12664	-0.992	-0.0653	No
106	MAPK13	Mapk13			12835	-1.057	-0.0665	No
107	CALM1	Calm1			13129	-1.174	-0.0745	No
108	CALM3	Calm3			13306	-1.252	-0.0743	No
109	PIK3CB	Pik3cb			13719	-1.479	-0.0872	No
110	PIK3R1	Pik3r1			13721	-1.480	-0.0734	No
111	CALM2	Calm2			13732	-1.487	-0.0602	No
112	CAMK2G	Camk2g			13858	-1.580	-0.0535	No
113	IRAK3	Irak3			14010	-1.702	-0.0474	No
114	CAMK2A	Camk2a			14142	-1.811	-0.0390	No
115	NFKB1	Nfkb1			14275	-1.949	-0.0293	No
116	SHC4	Shc4			14330	-2.013	-0.0140	No
117	JUN	Jun			14704	-2.538	-0.0145	No
118	ARHGDIB	Arhgdib			14869	-2.810	0.0011	No
119	CAMK2B	Camk2b			15410	-4.432	0.0075	No

Fig 2: KEGG_NEUROTROPHIN_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_NEUROTROPHIN_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_NEUROTROPHIN_SIGNALING_PATHWAY