Details for gene set KEGG_REGULATION_OF_ACTIN

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_HG.phenotype.cls#NGP_versus_HG_repos
Phenotype	phenotype.cls#NGP_versus_HG_repos
Upregulated in class	HG
GeneSet	KEGG_REGULATION_OF_ACTIN_CYTOSKELETON
Enrichment Score (ES)	-0.28337482
Normalized Enrichment Score (NES)	-1.5047853
Nominal p-value	0.0
FDR q-value	0.15386821
FWER p-Value	0.765

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FGF17	Fgf17	112	3.899	0.0143	No
2	PIP4K2C	Pip4k2c	322	3.238	0.0187	No
3	CYFIP2	Cyfip2	329	3.220	0.0361	No
4	EZR	Ezr	616	2.692	0.0324	No
5	ITGB7	Itgb7	810	2.407	0.0332	No
6	ITGA9	Itga9	822	2.396	0.0458	No
7	PIP5K1B	Pip5k1b	841	2.373	0.0578	No
8	GIT1	Git1	917	2.296	0.0656	No
9	SSH3	Ssh3	1061	2.131	0.0681	No
10	FGF22	Fgf22	1195	1.992	0.0705	No
11	CHRM1	Chrm1	1279	1.910	0.0757	No
12	ITGB5	Itgb5	1310	1.874	0.0841	No
13	FGFR3	Fgfr3	1358	1.838	0.0912	No
14	PIKFYVE	Pikfyve	1420	1.778	0.0971	No
15	PIK3CD	Pik3cd	1661	1.603	0.0904	No
16	NRAS	Nras	1999	1.405	0.0762	No
17	FGFR2	Fgfr2	2031	1.389	0.0819	No
18	ARHGEF6	Arhgef6	2061	1.378	0.0876	No
19	ENAH	Enah	2120	1.350	0.0913	No
20	PDGFB	Pdgfb	2294	1.269	0.0871	No
21	GNA13	Gna13	2383	1.233	0.0882	No
22	ITGB6	Itgb6	2499	1.178	0.0872	No
23	DIAPH2	Diaph2	2556	1.151	0.0900	No
24	FGF5	Fgf5	2817	1.046	0.0788	No
25	FGFR4	Fgfr4	2840	1.037	0.0831	No
26	APC2	Apc2	3148	0.936	0.0683	No
27	BCAR1	Bcar1	3392	0.865	0.0572	No
28	MYL12B	Myl12b	3439	0.856	0.0590	No
29	ITGA10	Gm42957	3450	0.853	0.0631	No
30	FGF11	Fgf11	3502	0.839	0.0644	No
31	FGF18	Fgf18	3517	0.834	0.0681	No
32	PIK3CG	Pik3cg	3524	0.831	0.0723	No
33	FN1	Fn1	3678	0.794	0.0668	No
34	WASL	Wasl	3722	0.784	0.0683	No
35	PIP5K1A	Pip5k1a	3748	0.776	0.0710	No
36	GNA12	Gna12	3817	0.756	0.0707	No
37	FGF23	Fgf23	3960	0.732	0.0655	No
38	MAPK3	Mapk3	4012	0.720	0.0662	No
39	PIP4K2A	Pip4k2a	4115	0.695	0.0634	No
40	PAK5	Pak7	4180	0.678	0.0630	No
41	MYH9	Myh9	4423	0.614	0.0506	No
42	ARHGAP35	Arhgap35	4541	0.582	0.0462	No
43	SOS2	Sos2	4544	0.582	0.0493	No
44	CHRM4	Chrm4	4578	0.575	0.0503	No
45	ARAF	Araf	4642	0.557	0.0493	No
46	CFL2	Cfl2	4849	0.507	0.0387	No
47	CHRM5	Chrm5	5312	0.428	0.0109	No
48	ITGB8	Itgb8	5402	0.417	0.0075	No
49	MYL10	Myl10	5411	0.415	0.0092	No
50	DIAPH1	Diaph1	5425	0.412	0.0107	No
51	BRAF	Braf	5445	0.408	0.0117	No
52	ITGA2B	Itga2b	5599	0.396	0.0039	No
53	ITGA3	Itga3	5667	0.382	0.0017	No
54	IQGAP1	Iqgap1	5698	0.375	0.0018	No
55	ARPC1A	Arpc1a	5719	0.369	0.0025	No
56	ARHGEF12	Arhgef12	5723	0.368	0.0044	No
57	VAV1	Vav1	5811	0.356	0.0007	No
58	VAV2	Vav2	6085	0.320	-0.0154	No
59	APC	Apc	6192	0.299	-0.0206	No
60	FGF2	Fgf2	6392	0.258	-0.0322	No
61	FGFR1	Fgfr1	6421	0.253	-0.0326	No
62	INSRR	Insrr	6454	0.246	-0.0333	No
63	FGD3	Fgd3	6466	0.241	-0.0327	No
64	CSK	Csk	6540	0.226	-0.0362	No
65	MRAS	Mras	6567	0.221	-0.0367	No
66	GNG12	Gng12	6617	0.212	-0.0387	No
67	ARPC4	Arpc4	6622	0.210	-0.0378	No
68	ARPC5	Arpc5	6673	0.201	-0.0399	No
69	LIMK1	Limk1	6779	0.181	-0.0458	No
70	F2	F2	6823	0.170	-0.0476	No
71	CHRM3	Chrm3	6842	0.166	-0.0479	No
72	NCKAP1	Nckap1	6888	0.157	-0.0499	No
73	ROCK1	Rock1	7085	0.119	-0.0621	No
74	CRK	Crk	7127	0.113	-0.0641	No
75	MSN	Msn	7312	0.075	-0.0757	No
76	SSH1	Ssh1	7359	0.067	-0.0783	No
77	PXN	Pxn	7416	0.059	-0.0816	No
78	ABI2	Abi2	7447	0.056	-0.0833	No
79	PIP5K1C	Pip5k1c	7567	0.035	-0.0909	No
80	PIK3CA	Pik3ca	7585	0.030	-0.0918	No
81	WAS	Was	7646	0.019	-0.0956	No
82	BDKRB2	Bdkrb2	7707	0.008	-0.0995	No
83	FGF9	Fgf9	7721	0.004	-0.1003	No
84	FGF6	Fgf6	7965	0.000	-0.1162	No
85	FGF19	Fgf15	8061	-0.009	-0.1223	No
86	MYLK3	Mylk3	8106	-0.017	-0.1251	No
87	LIMK2	Limk2	8144	-0.026	-0.1273	No
88	SOS1	Sos1	8166	-0.030	-0.1286	No
89	F2R	F2r	8183	-0.033	-0.1294	No
90	MYLK2	Mylk2	8447	-0.083	-0.1461	No
91	VAV3	Vav3	8467	-0.087	-0.1469	No
92	MYH14	Myh14	8506	-0.095	-0.1488	No
93	ARPC3	Arpc3	8527	-0.098	-0.1496	No
94	MYL2	Myl2	8535	-0.099	-0.1495	No
95	PAK6	Pak6	8612	-0.113	-0.1538	No
96	FGD1	Fgd1	8628	-0.115	-0.1542	No
97	ITGA5	Itga5	8800	-0.145	-0.1645	No
98	TIAM1	Tiam1	8817	-0.149	-0.1647	No
99	PIK3R5	Pik3r5	8900	-0.160	-0.1692	No
100	ITGAL	Itgal	8955	-0.169	-0.1718	No
101	RAC3	Rac3	9015	-0.180	-0.1746	No
102	PDGFA	Pdgfa	9111	-0.196	-0.1797	No
103	ACTN2	Actn2	9209	-0.215	-0.1849	No
104	RHOA	Rhoa	9229	-0.220	-0.1849	No
105	FGF12	Fgf12	9237	-0.221	-0.1841	No
106	RAC2	Rac2	9271	-0.227	-0.1850	No
107	HRAS	Hras	9287	-0.231	-0.1847	No
108	MAP2K1	Map2k1	9298	-0.232	-0.1841	No
109	WASF2	Wasf2	9358	-0.245	-0.1866	No
110	PFN1	Pfn1	9394	-0.252	-0.1874	No
111	ACTN1	Actn1	9458	-0.264	-0.1901	No
112	ARHGEF7	Arhgef7	9461	-0.264	-0.1887	No
113	ITGAM	Itgam	9504	-0.270	-0.1900	No
114	PAK4	Pak4	9515	-0.272	-0.1891	No
115	FGF10	Fgf10	9558	-0.280	-0.1903	No
116	ARPC2	Arpc2	9632	-0.295	-0.1934	No
117	CRKL	Crkl	9708	-0.310	-0.1966	No
118	PPP1R12A	Ppp1r12a	9753	-0.318	-0.1977	No
119	CFL1	Cfl1	9812	-0.332	-0.1997	No
120	ARPC1B	Arpc1b	9829	-0.334	-0.1989	No
121	PDGFC	Pdgfc	9842	-0.336	-0.1978	No
122	PAK3	Pak3	9856	-0.340	-0.1967	No
123	ACTB	Actb	10078	-0.384	-0.2090	No
124	SLC9A1	Slc9a1	10140	-0.396	-0.2108	No
125	ITGB1	Itgb1	10224	-0.414	-0.2139	No
126	ACTG1	Actg1	10326	-0.421	-0.2182	No
127	ITGA11	Itga11	10396	-0.426	-0.2203	No
128	PPP1CB	Ppp1cb	10446	-0.435	-0.2211	No
129	BAIAP2	Baiap2	10449	-0.435	-0.2188	No
130	ROCK2	Rock2	10537	-0.442	-0.2220	No
131	PAK2	Pak2	10634	-0.463	-0.2257	No
132	PFN2	Pfn2	10684	-0.475	-0.2263	No
133	MAPK1	Mapk1	10768	-0.489	-0.2290	No
134	CYFIP1	Cyfip1	10770	-0.491	-0.2263	No
135	MYLPF	Mylpf	10790	-0.494	-0.2248	No
136	CDC42	Cdc42	11074	-0.550	-0.2402	No
137	VCL	Vcl	11113	-0.558	-0.2396	No
138	KRAS	Kras	11151	-0.567	-0.2389	No
139	TIAM2	Tiam2	11232	-0.586	-0.2408	No
140	ARPC5L	Arpc5l	11253	-0.591	-0.2389	No
141	PIP4K2B	Pip4k2b	11350	-0.615	-0.2417	No
142	PTK2	Ptk2	11527	-0.655	-0.2496	No
143	RAF1	Raf1	11555	-0.662	-0.2477	No
144	FGF21	Fgf21	11557	-0.662	-0.2440	No
145	BRK1	Brk1	11580	-0.666	-0.2418	No
146	MYL12A	Myl12a	11642	-0.682	-0.2420	No
147	ITGAD	Itgad	11683	-0.694	-0.2407	No
148	ITGA7	Itga7	11843	-0.740	-0.2470	No
149	ITGAV	Itgav	12032	-0.796	-0.2549	No
150	PPP1CA	Ppp1ca	12259	-0.857	-0.2648	No
151	ARHGEF1	Arhgef1	12307	-0.869	-0.2631	No
152	RAC1	Rac1	12614	-0.976	-0.2776	No
153	TMSB4X	Tmsb4x	12703	-1.008	-0.2778	Yes
154	PPP1CC	Ppp1cc	12721	-1.015	-0.2733	Yes
155	SSH2	Ssh2	12732	-1.019	-0.2683	Yes
156	MYL9	Myl9	12847	-1.060	-0.2698	Yes
157	SCIN	Scin	13005	-1.122	-0.2738	Yes
158	MYH10	Myh10	13018	-1.127	-0.2684	Yes
159	DOCK1	Dock1	13026	-1.132	-0.2625	Yes
160	PAK1	Pak1	13152	-1.182	-0.2641	Yes
161	EGF	Egf	13161	-1.188	-0.2581	Yes
162	MYL7	Myl7	13295	-1.248	-0.2598	Yes
163	RRAS	Rras	13300	-1.249	-0.2531	Yes
164	RDX	Rdx	13370	-1.294	-0.2505	Yes
165	ACTN4	Actn4	13388	-1.302	-0.2443	Yes
166	FGF7	Fgf7	13408	-1.311	-0.2383	Yes
167	WASF1	Wasf1	13411	-1.313	-0.2312	Yes
168	FGF14	Fgf14	13412	-1.313	-0.2239	Yes
169	ITGA8	Itga8	13437	-1.329	-0.2181	Yes
170	GSN	Gsn	13471	-1.343	-0.2128	Yes
171	MOS	Mos	13547	-1.385	-0.2100	Yes
172	PIK3CB	Pik3cb	13719	-1.479	-0.2129	Yes
173	PIK3R1	Pik3r1	13721	-1.480	-0.2048	Yes
174	RRAS2	Rras2	13860	-1.582	-0.2050	Yes
175	ITGB4	Itgb4	14125	-1.795	-0.2123	Yes
176	ITGA6	Itga6	14158	-1.823	-0.2042	Yes
177	BDKRB1	Bdkrb1	14206	-1.872	-0.1969	Yes
178	PFN4	Pfn4	14217	-1.884	-0.1871	Yes
179	ITGA4	Itga4	14396	-2.091	-0.1871	Yes
180	PDGFRA	Pdgfra	14432	-2.130	-0.1776	Yes
181	PDGFD	Pdgfd	14454	-2.166	-0.1669	Yes
182	PDGFRB	Pdgfrb	14505	-2.226	-0.1578	Yes
183	EGFR	Egfr	14536	-2.270	-0.1472	Yes
184	CD14	Cd14	14584	-2.340	-0.1373	Yes
185	ITGA1	Itga1	14614	-2.383	-0.1259	Yes
186	IQGAP2	Iqgap2	14642	-2.438	-0.1142	Yes
187	ITGA2	Itga2	14691	-2.524	-0.1033	Yes
188	ACTN3	Actn3	14766	-2.627	-0.0935	Yes
189	MYLK	Mylk	14799	-2.685	-0.0807	Yes
190	ITGAE	Itgae	15042	-3.244	-0.0785	Yes
191	NCKAP1L	Nckap1l	15145	-3.560	-0.0654	Yes
192	FGF1	Fgf1	15206	-3.722	-0.0487	Yes
193	ITGAX	Itgax	15301	-4.050	-0.0323	Yes
194	DIAPH3	Diaph3	15343	-4.194	-0.0117	Yes
195	IQGAP3	Iqgap3	15355	-4.245	0.0111	Yes