Details for gene set KEGG_CELL_CYCLE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_CELL_CYCLE
Enrichment Score (ES)	-0.6553098
Normalized Enrichment Score (NES)	-2.522597
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_CELL_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GADD45A	Gadd45a			287	2.360	-0.0049	No
2	MDM2	Mdm2			859	1.605	-0.0326	No
3	PRKDC	Prkdc			1405	1.257	-0.0606	No
4	EP300	Ep300			1481	1.221	-0.0584	No
5	RB1	Rb1			1859	1.074	-0.0766	No
6	ZBTB17	Zbtb17			1863	1.072	-0.0706	No
7	CREBBP	Crebbp			2281	0.921	-0.0923	No
8	SMAD2	Smad2			2479	0.869	-0.1000	No
9	SMAD3	Smad3			3257	0.699	-0.1464	No
10	GSK3B	Gsk3b			3289	0.693	-0.1443	No
11	SMAD4	Smad4			3536	0.639	-0.1566	No
12	SFN	Sfn			3543	0.638	-0.1532	No
13	ATM	Atm			3647	0.615	-0.1563	No
14	ANAPC2	Anapc2			3840	0.569	-0.1655	No
15	SMC1B	Smc1b			4537	0.453	-0.2080	No
16	CDK4	Cdk4			4881	0.408	-0.2279	No
17	CDKN1A	Cdkn1a			5155	0.378	-0.2434	No
18	WEE2	Wee2			5307	0.356	-0.2511	No
19	STAG2	Stag2			5503	0.341	-0.2618	No
20	ORC3	Orc3			5772	0.294	-0.2775	No
21	RBL2	Rbl2			5898	0.274	-0.2840	No
22	YWHAG	Ywhag			6117	0.240	-0.2968	No
23	CCNB3	Ccnb3			6667	0.148	-0.3315	No
24	ABL1	Abl1			6836	0.119	-0.3417	No
25	SKP1	Skp1a			7132	0.074	-0.3605	No
26	CDC16	Cdc16			7331	0.044	-0.3730	No
27	CDC27	Cdc27			8247	-0.057	-0.4321	No
28	ORC4	Orc4			8296	-0.065	-0.4348	No
29	RBX1	Rbx1			8648	-0.115	-0.4569	No
30	ANAPC1	Anapc1			8685	-0.120	-0.4586	No
31	ANAPC4	Anapc4			8725	-0.128	-0.4604	No
32	GADD45B	Gadd45b			8870	-0.149	-0.4688	No
33	MAD2L2	Mad2l2			8884	-0.151	-0.4688	No
34	E2F5	E2f5			8895	-0.152	-0.4686	No
35	ANAPC10	Anapc10			9445	-0.234	-0.5028	No
36	CCNH	Ccnh			9469	-0.237	-0.5029	No
37	STAG1	Stag1			9517	-0.245	-0.5046	No
38	CDKN1C	Cdkn1c			9635	-0.261	-0.5106	No
39	YWHAB	Ywhab			9670	-0.266	-0.5113	No
40	ATR	Atr			9758	-0.283	-0.5153	No
41	TP53	Trp53			9922	-0.312	-0.5241	No
42	CUL1	Cul1			9979	-0.320	-0.5258	No
43	YWHAZ	Ywhaz			10001	-0.323	-0.5253	No
44	CDC26	Cdc26			10084	-0.337	-0.5287	No
45	ANAPC5	Anapc5			10206	-0.364	-0.5344	No
46	E2F3	E2f3			10310	-0.381	-0.5389	No
47	YWHAQ	Ywhaq			10604	-0.421	-0.5554	No
48	HDAC2	Hdac2			10806	-0.436	-0.5659	No
49	YWHAE	Ywhae			10828	-0.440	-0.5647	No
50	CDK7	Cdk7			10885	-0.449	-0.5658	No
51	YWHAH	Ywhah			10915	-0.456	-0.5650	No
52	PCNA	Pcna			11511	-0.560	-0.6003	No
53	CCND3	Ccnd3			11584	-0.575	-0.6017	No
54	ANAPC7	Anapc7			11689	-0.596	-0.6050	No
55	MAD1L1	Mad1l1			11874	-0.636	-0.6132	No
56	TGFB2	Tgfb2			11914	-0.646	-0.6120	No
57	CDC14A	Cdc14a			11927	-0.649	-0.6090	No
58	TGFB1	Tgfb1			12016	-0.671	-0.6108	No
59	CDC25B	Cdc25b			12065	-0.682	-0.6099	No
60	CDKN1B	Cdkn1b			12157	-0.705	-0.6117	No
61	BUB3	Bub3			12181	-0.710	-0.6091	No
62	CCNA1	Ccna1			12301	-0.740	-0.6125	No
63	ANAPC13	Anapc13			12419	-0.766	-0.6156	No
64	SMC1A	Smc1a			12461	-0.775	-0.6138	No
65	E2F4	E2f4			12642	-0.823	-0.6207	No
66	TFDP2	Tfdp2			12746	-0.846	-0.6224	No
67	MYC	Myc			12942	-0.905	-0.6298	No
68	CDC25A	Cdc25a			13161	-0.974	-0.6383	No
69	SMC3	Smc3			13232	-1.004	-0.6370	No
70	CDK6	Cdk6			13323	-1.045	-0.6368	No
71	E2F1	E2f1			13461	-1.093	-0.6393	No
72	FZR1	Fzr1			13466	-1.093	-0.6332	No
73	HDAC1	Hdac1			13793	-1.225	-0.6472	No
74	CDK2	Cdk2			13919	-1.295	-0.6478	Yes
75	RAD21	Rad21			13971	-1.318	-0.6434	Yes
76	ORC5	Orc5			13985	-1.327	-0.6365	Yes
77	TFDP1	Tfdp1			14006	-1.336	-0.6300	Yes
78	WEE1	Wee1			14060	-1.370	-0.6255	Yes
79	MCM7	Mcm7			14300	-1.525	-0.6321	Yes
80	CDC23	Cdc23			14399	-1.616	-0.6291	Yes
81	CHEK2	Chek2			14458	-1.668	-0.6232	Yes
82	GADD45G	Gadd45g			14592	-1.803	-0.6213	Yes
83	TGFB3	Tgfb3			14691	-1.893	-0.6166	Yes
84	ORC2	Orc2			14773	-1.989	-0.6103	Yes
85	DBF4	Dbf4			14780	-1.994	-0.5991	Yes
86	MCM2	Mcm2			14827	-2.038	-0.5902	Yes
87	SKP2	Skp2			14869	-2.091	-0.5807	Yes
88	E2F2	E2f2			14953	-2.242	-0.5730	Yes
89	ORC6	Orc6			14990	-2.313	-0.5619	Yes
90	CDC7	Cdc7			15033	-2.387	-0.5508	Yes
91	MCM4	Mcm4			15094	-2.529	-0.5399	Yes
92	CCND1	Ccnd1			15096	-2.535	-0.5252	Yes
93	CDKN2D	Cdkn2d			15186	-2.823	-0.5146	Yes
94	PKMYT1	Pkmyt1			15188	-2.827	-0.4982	Yes
95	CDKN2C	Cdkn2c			15228	-2.983	-0.4834	Yes
96	RBL1	Rbl1			15270	-3.172	-0.4676	Yes
97	MCM6	Mcm6			15295	-3.297	-0.4499	Yes
98	ORC1	Orc1			15315	-3.391	-0.4314	Yes
99	MCM3	Mcm3			15319	-3.408	-0.4118	Yes
100	MAD2L1	Mad2l1			15336	-3.510	-0.3924	Yes
101	CHEK1	Chek1			15361	-3.652	-0.3727	Yes
102	CDK1	Cdk1			15367	-3.695	-0.3515	Yes
103	CCNE1	Ccne1			15394	-3.949	-0.3302	Yes
104	CDC45	Cdc45			15398	-4.001	-0.3071	Yes
105	CCNE2	Ccne2			15410	-4.096	-0.2840	Yes
106	MCM5	Mcm5			15420	-4.154	-0.2604	Yes
107	CDC20	Cdc20			15468	-4.434	-0.2376	Yes
108	CDC25C	Cdc25c			15470	-4.435	-0.2119	Yes
109	ESPL1	Espl1			15483	-4.511	-0.1864	Yes
110	CCNB2	Ccnb2			15491	-4.557	-0.1603	Yes
111	CCNB1	Ccnb1			15492	-4.568	-0.1337	Yes
112	CDC6	Cdc6			15495	-4.576	-0.1072	Yes
113	BUB1	Bub1			15499	-4.609	-0.0806	Yes
114	TTK	Ttk			15503	-4.625	-0.0539	Yes
115	PLK1	Plk1			15517	-4.730	-0.0272	Yes
116	CCNA2	Ccna2			15521	-4.748	0.0003	Yes

Fig 2: KEGG_CELL_CYCLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_CELL_CYCLE: Random ES distribution   
Gene set null distribution of ES for KEGG_CELL_CYCLE