Details for gene set KEGG_PARKINSONS_DISEASE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_PARKINSONS_DISEASE
Enrichment Score (ES)	-0.44820452
Normalized Enrichment Score (NES)	-1.7317423
Nominal p-value	0.0
FDR q-value	0.02326611
FWER p-Value	0.241

Fig 1: Enrichment plot: KEGG_PARKINSONS_DISEASE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SLC25A31	Slc25a31			436	2.108	-0.0002	No
2	SNCA	Snca			939	1.538	-0.0123	No
3	SNCAIP	Sncaip			967	1.521	0.0062	No
4	CASP9	Casp9			1138	1.403	0.0139	No
5	COX7A2L	Cox7a2l			1253	1.335	0.0243	No
6	SLC18A1	Slc18a1			2513	0.864	-0.0459	No
7	PINK1	Pink1			2848	0.785	-0.0571	No
8	UCHL1	Uchl1			2854	0.783	-0.0470	No
9	NDUFA6	Ndufa6			2870	0.780	-0.0376	No
10	COX4I2	Cox4i2			2876	0.778	-0.0275	No
11	MT-CO1	mt-Co1			4912	0.401	-0.1542	No
12	SLC6A3	Slc6a3			5390	0.356	-0.1804	No
13	MT-ND4L	mt-Nd4l			5400	0.356	-0.1762	No
14	APAF1	Apaf1			5922	0.272	-0.2064	No
15	NDUFS2	Ndufs2			6088	0.245	-0.2139	No
16	PRKN	Prkn			6186	0.229	-0.2171	No
17	MT-ND4	mt-Nd4			6515	0.173	-0.2361	No
18	UBE2J1	Ube2j1			6767	0.130	-0.2506	No
19	MT-ND1	mt-Nd1			7022	0.089	-0.2659	No
20	NDUFB2	Ndufb2			7448	0.026	-0.2931	No
21	UQCRFS1	Uqcrfs1			7519	0.017	-0.2974	No
22	MT-ATP6	mt-Atp6			7689	0.000	-0.3084	No
23	MT-CO3	mt-Co3			7787	0.000	-0.3147	No
24	COX4I1	Cox4i1			8028	-0.025	-0.3299	No
25	UBA1	Uba1			8064	-0.030	-0.3318	No
26	MT-ND2	mt-Nd2			8167	-0.045	-0.3378	No
27	MT-ND6	mt-Nd6			8316	-0.068	-0.3465	No
28	CASP3	Casp3			8435	-0.085	-0.3530	No
29	MT-ND5	mt-Nd5			8443	-0.086	-0.3523	No
30	MT-CYB	mt-Cytb			8723	-0.128	-0.3687	No
31	SLC18A2	Slc18a2			8745	-0.131	-0.3684	No
32	NDUFB9	Ndufb9			9475	-0.238	-0.4125	No
33	SLC25A4	Slc25a4			9501	-0.243	-0.4109	No
34	NDUFB5	Ndufb5			9733	-0.280	-0.4221	No
35	COX6B1	Cox6b1			9788	-0.286	-0.4218	No
36	UBE2J2	Ube2j2			9805	-0.290	-0.4190	No
37	NDUFA10	Ndufa10			9814	-0.293	-0.4156	No
38	NDUFV1	Ndufv1			9824	-0.293	-0.4123	No
39	UBB	Ubb			9924	-0.312	-0.4145	No
40	COX7B	Cox7b			10104	-0.341	-0.4216	No
41	VDAC2	Vdac2			10247	-0.371	-0.4259	No
42	COX7C	Cox7c			10405	-0.397	-0.4308	No
43	COX7B2	Cox7b2			10634	-0.421	-0.4399	No
44	COX7A2	Cox7a2			10704	-0.427	-0.4387	No
45	SDHC	Sdhc			10851	-0.443	-0.4423	Yes
46	LRRK2	Lrrk2			10858	-0.444	-0.4368	Yes
47	UBE2G1	Ube2g1			10884	-0.449	-0.4324	Yes
48	NDUFS3	Ndufs3			10977	-0.465	-0.4322	Yes
49	MT-CO2	mt-Co2			11133	-0.487	-0.4358	Yes
50	NDUFB3	Ndufb3			11235	-0.505	-0.4356	Yes
51	COX8C	Cox8b			11277	-0.512	-0.4314	Yes
52	CYC1	Cyc1			11289	-0.515	-0.4253	Yes
53	UQCRC2	Uqcrc2			11303	-0.518	-0.4192	Yes
54	NDUFB1	Ndufb1-ps			11347	-0.526	-0.4150	Yes
55	NDUFS1	Ndufs1			11400	-0.535	-0.4113	Yes
56	ATP5F1C	Atp5c1			11459	-0.548	-0.4077	Yes
57	NDUFB4	Ndufb4			11466	-0.550	-0.4008	Yes
58	PPID	Ppid			11603	-0.578	-0.4019	Yes
59	NDUFA8	Ndufa8			11633	-0.584	-0.3960	Yes
60	NDUFA1	Ndufa1			11658	-0.590	-0.3897	Yes
61	VDAC3	Vdac3			11871	-0.635	-0.3950	Yes
62	NDUFB6	Ndufb6			11978	-0.661	-0.3931	Yes
63	COX5A	Cox5a			12040	-0.676	-0.3880	Yes
64	SLC25A5	Slc25a5			12066	-0.682	-0.3805	Yes
65	NDUFAB1	Ndufab1			12069	-0.683	-0.3716	Yes
66	NDUFA9	Ndufa9			12260	-0.729	-0.3742	Yes
67	NDUFA2	Ndufa2			12284	-0.734	-0.3659	Yes
68	UQCRQ	Uqcrq			12315	-0.742	-0.3580	Yes
69	NDUFS8	Ndufs8			12364	-0.755	-0.3510	Yes
70	ATP5PF	Atp5j			12388	-0.760	-0.3424	Yes
71	NDUFS7	Ndufs7			12392	-0.763	-0.3324	Yes
72	NDUFS6	Ndufs6			12410	-0.765	-0.3233	Yes
73	SDHB	Sdhb			12441	-0.770	-0.3150	Yes
74	COX6A2	Cox6a2			12497	-0.785	-0.3081	Yes
75	NDUFA3	Ndufa3			12510	-0.788	-0.2984	Yes
76	ATP5PD	Atp5h			12515	-0.789	-0.2882	Yes
77	PARK7	Park7			12517	-0.790	-0.2777	Yes
78	VDAC1	Vdac1			12573	-0.806	-0.2706	Yes
79	ATP5F1A	Atp5a1			12609	-0.813	-0.2620	Yes
80	ATP5F1E	Atp5e			12626	-0.818	-0.2521	Yes
81	NDUFS4	Ndufs4			12711	-0.837	-0.2464	Yes
82	NDUFB7	Ndufb7			12713	-0.838	-0.2353	Yes
83	ATP5MC3	Atp5g3			12728	-0.842	-0.2250	Yes
84	NDUFB10	Ndufb10			12741	-0.845	-0.2146	Yes
85	ATP5F1D	Atp5d			12832	-0.865	-0.2089	Yes
86	COX5B	Cox5b			12858	-0.875	-0.1989	Yes
87	COX8A	Cox8a			12920	-0.897	-0.1909	Yes
88	UQCRC1	Uqcrc1			12932	-0.902	-0.1796	Yes
89	NDUFA4	Ndufa4			12975	-0.914	-0.1701	Yes
90	UQCRB	Uqcrb			12991	-0.917	-0.1589	Yes
91	NDUFV3	Ndufv3			13106	-0.957	-0.1535	Yes
92	ATP5F1B	Atp5b			13119	-0.961	-0.1415	Yes
93	COX6C	Cox6c			13135	-0.967	-0.1296	Yes
94	CYCS	Cycs			13225	-1.002	-0.1220	Yes
95	COX6B2	Cox6b2			13229	-1.003	-0.1089	Yes
96	NDUFV2	Ndufv2			13351	-1.057	-0.1026	Yes
97	UBA7	Uba7			13386	-1.070	-0.0906	Yes
98	COX6A1	Cox6a1			13416	-1.080	-0.0781	Yes
99	NDUFC1	Ndufc1			13643	-1.161	-0.0773	Yes
100	UQCR10	Uqcr10			13754	-1.211	-0.0683	Yes
101	HTRA2	Htra2			13941	-1.305	-0.0630	Yes
102	NDUFS5	Ndufs5			14012	-1.341	-0.0497	Yes
103	UBE2G2	Ube2g2			14027	-1.350	-0.0326	Yes
104	NDUFA5	Ndufa5			14340	-1.554	-0.0321	Yes
105	UBE2L6	Ube2l6			14515	-1.727	-0.0204	Yes
106	COX7A1	Cox7a1			14746	-1.951	-0.0093	Yes
107	NDUFA4L2	Ndufa4l2			14864	-2.080	0.0108	Yes
108	TH	Th			15041	-2.405	0.0314	Yes

Fig 2: KEGG_PARKINSONS_DISEASE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_PARKINSONS_DISEASE: Random ES distribution   
Gene set null distribution of ES for KEGG_PARKINSONS_DISEASE