Details for gene set KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	NGP
GeneSet	KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM
Enrichment Score (ES)	0.31263858
Normalized Enrichment Score (NES)	1.2217058
Nominal p-value	0.12328767
FDR q-value	0.5966352
FWER p-Value	1.0

Fig 1: Enrichment plot: KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIP5K1B	Pip5k1b			228	2.492	0.0282	Yes
2	CDS1	Cds1			234	2.470	0.0705	Yes
3	INPP5D	Inpp5d			521	1.970	0.0860	Yes
4	PIP4K2C	Pip4k2c			654	1.826	0.1090	Yes
5	DGKQ	Dgkq			671	1.808	0.1392	Yes
6	PLCG1	Plcg1			698	1.760	0.1678	Yes
7	PIKFYVE	Pikfyve			925	1.543	0.1799	Yes
8	DGKH	Dgkh			963	1.522	0.2037	Yes
9	INPP4A	Inpp4a			1169	1.391	0.2145	Yes
10	DGKD	Dgkd			1200	1.362	0.2360	Yes
11	ITPR3	Itpr3			1202	1.362	0.2594	Yes
12	PIK3CD	Pik3cd			1218	1.353	0.2818	Yes
13	PIK3C2A	Pik3c2a			1283	1.321	0.3005	Yes
14	INPP5E	Inpp5e			1543	1.197	0.3043	Yes
15	ITPR2	Itpr2			1842	1.079	0.3037	Yes
16	PLCG2	Plcg2			2250	0.934	0.2935	Yes
17	INPPL1	Inppl1			2365	0.899	0.3016	Yes
18	CDS2	Cds2			2431	0.883	0.3126	Yes
19	INPP5J	Inpp5j			2828	0.788	0.3006	No
20	PLCB4	Plcb4			3120	0.733	0.2944	No
21	PIK3C3	Pik3c3			3322	0.686	0.2933	No
22	PIK3CA	Pik3ca			3461	0.655	0.2956	No
23	SYNJ1	Synj1			4016	0.538	0.2691	No
24	PIP5K1A	Pip5k1a			4047	0.532	0.2763	No
25	DGKI	Dgki			5011	0.401	0.2209	No
26	PLCB2	Plcb2			5198	0.371	0.2153	No
27	DGKA	Dgka			5212	0.369	0.2208	No
28	PI4KB	Pi4kb			6046	0.251	0.1712	No
29	PLCD3	Plcd3			6108	0.241	0.1714	No
30	PIP4K2A	Pip4k2a			6272	0.213	0.1646	No
31	PIK3C2B	Pik3c2b			6303	0.207	0.1662	No
32	INPP5A	Inpp5a			6461	0.183	0.1592	No
33	ITPR1	Itpr1			6560	0.165	0.1557	No
34	SYNJ2	Synj2			6743	0.135	0.1463	No
35	CALML3	Calml3			6917	0.107	0.1369	No
36	PIP5K1C	Pip5k1c			6949	0.102	0.1367	No
37	PIP4K2B	Pip4k2b			7074	0.082	0.1301	No
38	PIK3CG	Pik3cg			7113	0.076	0.1289	No
39	PLCD1	Plcd1			7313	0.047	0.1168	No
40	ITPKB	Itpkb			7931	-0.007	0.0770	No
41	PLCB3	Plcb3			8062	-0.030	0.0691	No
42	ITPK1	Itpk1			8226	-0.053	0.0595	No
43	PRKCG	Prkcg			8709	-0.126	0.0305	No
44	PI4KA	Pi4ka			8811	-0.143	0.0264	No
45	PTEN	Pten			8901	-0.154	0.0233	No
46	IMPA1	Impa1			8989	-0.167	0.0206	No
47	PIK3C2G	Pik3c2g			8996	-0.167	0.0231	No
48	DGKG	Dgkg			9051	-0.172	0.0225	No
49	INPP5K	Inpp5k			9144	-0.186	0.0198	No
50	IPPK	Ippk			9885	-0.305	-0.0228	No
51	DGKZ	Dgkz			10316	-0.382	-0.0441	No
52	DGKE	Dgke			10850	-0.443	-0.0709	No
53	INPP1	Inpp1			10928	-0.458	-0.0680	No
54	PLCD4	Plcd4			10937	-0.460	-0.0606	No
55	PRKCA	Prkca			11139	-0.487	-0.0652	No
56	CDIPT	Cdipt			11267	-0.510	-0.0646	No
57	PLCE1	Plce1			11369	-0.530	-0.0620	No
58	PIK3R5	Pik3r5			11573	-0.572	-0.0652	No
59	OCRL	Ocrl			11611	-0.581	-0.0576	No
60	INPP5B	Inpp5b			11683	-0.595	-0.0519	No
61	ITPKA	Itpka			11762	-0.611	-0.0465	No
62	DGKB	Dgkb			12383	-0.758	-0.0735	No
63	PIK3R1	Pik3r1			13222	-1.001	-0.1104	No
64	CALM3	Calm3			13425	-1.084	-0.1048	No
65	CALM2	Calm2			13917	-1.295	-0.1142	No
66	PIK3CB	Pik3cb			14292	-1.520	-0.1122	No
67	CALM1	Calm1			14310	-1.533	-0.0869	No
68	INPP4B	Inpp4b			14849	-2.062	-0.0861	No
69	IMPA2	Impa2			14906	-2.149	-0.0527	No
70	PRKCB	Prkcb			15007	-2.336	-0.0188	No
71	PLCB1	Plcb1			15237	-3.030	0.0186	No

Fig 2: KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM: Random ES distribution   
Gene set null distribution of ES for KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM