Details for gene set KEGG_PYRIMIDINE

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_PYRIMIDINE_METABOLISM
Enrichment Score (ES)	-0.547432
Normalized Enrichment Score (NES)	-2.0411935
Nominal p-value	0.0
FDR q-value	3.0200157E-4
FWER p-Value	0.002

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	POLR2A	Polr2a	1279	1.322	-0.0683	No
2	DPYS	Dpys	1514	1.209	-0.0701	No
3	UCKL1	Uckl1	1530	1.202	-0.0578	No
4	UPB1	Upb1	1537	1.198	-0.0450	No
5	POLR3A	Polr3a	2144	0.970	-0.0735	No
6	TXNRD1	Txnrd1	2310	0.914	-0.0741	No
7	POLR1C	Polr1c	2676	0.827	-0.0887	No
8	ENTPD3	Entpd3	3060	0.741	-0.1053	No
9	UPRT	Uprt	4085	0.525	-0.1658	No
10	ENTPD8	Entpd8	4359	0.479	-0.1782	No
11	POLR3F	Polr3f	4510	0.458	-0.1829	No
12	NME5	Nme5	4530	0.454	-0.1791	No
13	NT5C	Nt5c	4717	0.430	-0.1864	No
14	CANT1	Cant1	5083	0.390	-0.2058	No
15	NME4	Nme4	5785	0.293	-0.2479	No
16	AK3	Ak3	6361	0.197	-0.2830	No
17	POLR3C	Polr3c	6439	0.187	-0.2859	No
18	POLR2K	Polr2k	6533	0.170	-0.2901	No
19	CTPS2	Ctps2	6562	0.165	-0.2901	No
20	POLR3B	Polr3b	6660	0.148	-0.2947	No
21	TK2	Tk2	6873	0.113	-0.3072	No
22	TXNRD2	Txnrd2	7070	0.082	-0.3190	No
23	POLR1D	Polr1d	7211	0.062	-0.3274	No
24	RRM2B	Rrm2b	7528	0.015	-0.3477	No
25	POLR2E	Polr2e	7885	-0.000	-0.3707	No
26	POLR2B	Polr2b	8603	-0.111	-0.4159	No
27	POLE4	Pole4	8754	-0.132	-0.4242	No
28	POLR3D	Polr3d	8818	-0.144	-0.4267	No
29	ENTPD5	Entpd5	9114	-0.181	-0.4438	No
30	NME7	Nme7	9923	-0.312	-0.4927	No
31	POLR2H	Polr2h	10136	-0.349	-0.5026	No
32	CMPK1	Cmpk1	10562	-0.411	-0.5256	No
33	ENTPD4	Entpd4b	10733	-0.432	-0.5318	No
34	POLR1A	Polr1a	10830	-0.440	-0.5332	No
35	POLR2G	Polr2g	10854	-0.443	-0.5298	No
36	CMPK2	Cmpk2	10890	-0.450	-0.5271	No
37	NUDT2	Nudt2	10960	-0.463	-0.5264	No
38	ZNRD1	Znrd1	11035	-0.476	-0.5260	No
39	POLR2I	Polr2i	11145	-0.489	-0.5277	No
40	NT5C2	Nt5c2	11291	-0.515	-0.5314	No
41	TYMP	Tymp	11295	-0.516	-0.5259	No
42	NT5C3A	Nt5c3	11318	-0.519	-0.5216	No
43	POLR3K	Polr3k	11577	-0.573	-0.5320	No
44	POLR1E	Polr1e	11668	-0.593	-0.5313	No
45	POLR2F	Polr2f	11750	-0.606	-0.5298	No
46	NME1	Nme1	11779	-0.614	-0.5249	No
47	POLR2C	Polr2c	11845	-0.629	-0.5221	No
48	PNP	Pnp	11964	-0.658	-0.5225	No
49	UPP1	Upp1	11990	-0.663	-0.5168	No
50	NME6	Nme6	12074	-0.684	-0.5147	No
51	POLR2L	Polr2l	12313	-0.742	-0.5219	No
52	NME2	Nme2	12378	-0.757	-0.5177	No
53	ENTPD6	Entpd6	12567	-0.804	-0.5210	No
54	UCK1	Uck1	12833	-0.865	-0.5287	No
55	CAD	Cad	13124	-0.964	-0.5368	Yes
56	NT5M	Nt5m	13236	-1.007	-0.5329	Yes
57	UPP2	Upp2	13281	-1.029	-0.5244	Yes
58	UCK2	Uck2	13407	-1.077	-0.5206	Yes
59	POLR2D	Polr2d	13573	-1.136	-0.5188	Yes
60	ENTPD1	Entpd1	13706	-1.190	-0.5142	Yes
61	POLR1B	Polr1b	13708	-1.191	-0.5012	Yes
62	UMPS	Umps	13859	-1.260	-0.4970	Yes
63	PNPT1	Pnpt1	13876	-1.270	-0.4840	Yes
64	DPYD	Dpyd	14014	-1.341	-0.4781	Yes
65	DHODH	Dhodh	14051	-1.364	-0.4654	Yes
66	DCTD	Dctd	14227	-1.477	-0.4604	Yes
67	POLD1	Pold1	14287	-1.514	-0.4476	Yes
68	POLR3H	Polr3h	14483	-1.689	-0.4416	Yes
69	DTYMK	Dtymk	14485	-1.692	-0.4230	Yes
70	POLE3	Pole3	14552	-1.771	-0.4077	Yes
71	CDA	Cda	14616	-1.831	-0.3916	Yes
72	CTPS1	Ctps	14766	-1.979	-0.3795	Yes
73	ITPA	Itpa	14791	-2.005	-0.3589	Yes
74	POLD2	Pold2	14805	-2.019	-0.3375	Yes
75	POLE2	Pole2	14892	-2.125	-0.3196	Yes
76	NT5E	Nt5e	14899	-2.139	-0.2964	Yes
77	PRIM2	Prim2	15147	-2.715	-0.2825	Yes
78	DUT	Dut	15162	-2.753	-0.2531	Yes
79	DCK	Dck	15218	-2.933	-0.2243	Yes
80	TYMS	Tyms	15273	-3.185	-0.1927	Yes
81	RRM1	Rrm1	15294	-3.282	-0.1578	Yes
82	POLA1	Pola1	15332	-3.491	-0.1217	Yes
83	POLE	Pole	15345	-3.558	-0.0832	Yes
84	TK1	Tk1	15397	-3.985	-0.0426	Yes
85	RRM2	Rrm2	15500	-4.610	0.0016	Yes