Details for gene set KEGG_SPLICEOSOME[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	LG
GeneSet	KEGG_SPLICEOSOME
Enrichment Score (ES)	-0.42828196
Normalized Enrichment Score (NES)	-1.6373243
Nominal p-value	0.0
FDR q-value	0.04644959
FWER p-Value	0.541

Fig 1: Enrichment plot: KEGG_SPLICEOSOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HSPA8	Hspa8			348	2.249	0.0047	No
2	THOC2	Thoc2			844	1.618	-0.0078	No
3	PRPF40B	Prpf40b			1334	1.294	-0.0239	No
4	DHX8	Dhx8			1828	1.086	-0.0427	No
5	THOC1	Thoc1			2811	0.791	-0.0968	No
6	SNRNP200	Snrnp200			2835	0.787	-0.0888	No
7	SF3B3	Sf3b3			3005	0.751	-0.0906	No
8	SRSF5	Srsf5			3227	0.706	-0.0964	No
9	SF3B2	Sf3b2			3791	0.580	-0.1259	No
10	DDX39B	Ddx39b			4049	0.532	-0.1361	No
11	SF3B1	Sf3b1			4132	0.515	-0.1352	No
12	XAB2	Xab2			4291	0.489	-0.1395	No
13	BCAS2	Bcas2			4476	0.462	-0.1459	No
14	SLU7	Slu7			4562	0.449	-0.1459	No
15	DHX38	Dhx38			4598	0.443	-0.1428	No
16	DHX16	Dhx16			5096	0.388	-0.1704	No
17	SYF2	Syf2			5097	0.388	-0.1657	No
18	PUF60	Puf60			5122	0.384	-0.1626	No
19	U2SURP	U2surp			5124	0.383	-0.1580	No
20	PRPF8	Prpf8			5213	0.368	-0.1592	No
21	PCBP1	Pcbp1			5513	0.340	-0.1745	No
22	PRPF6	Prpf6			5991	0.260	-0.2023	No
23	PLRG1	Plrg1			6453	0.184	-0.2300	No
24	CRNKL1	Crnkl1			6554	0.167	-0.2345	No
25	DDX42	Ddx42			6640	0.152	-0.2382	No
26	CHERP	Cherp			6661	0.148	-0.2377	No
27	U2AF2	U2af2			6663	0.148	-0.2359	No
28	SF3B4	Sf3b4			6941	0.103	-0.2526	No
29	HSPA2	Hspa2			7011	0.092	-0.2560	No
30	AQR	Aqr			7173	0.067	-0.2656	No
31	SF3A2	Sf3a2			7450	0.025	-0.2832	No
32	RBM8A	Rbm8a			8068	-0.030	-0.3229	No
33	DDX23	Ddx23			8134	-0.040	-0.3266	No
34	SNRPA	Snrpa			8270	-0.060	-0.3347	No
35	TXNL4A	Txnl4a			8335	-0.071	-0.3380	No
36	HNRNPK	Hnrnpk			8571	-0.104	-0.3520	No
37	SNW1	Snw1			8839	-0.146	-0.3675	No
38	SMNDC1	Smndc1			8905	-0.154	-0.3699	No
39	RBM17	Rbm17			9162	-0.188	-0.3842	No
40	SNRNP70	Snrnp70			9272	-0.205	-0.3888	No
41	RBM22	Rbm22			9274	-0.206	-0.3863	No
42	CTNNBL1	Ctnnbl1			9344	-0.218	-0.3882	No
43	SNRPC	Snrpc			9592	-0.254	-0.4011	No
44	SNRPB	Snrpb			9706	-0.274	-0.4051	No
45	SF3A1	Sf3a1			9961	-0.317	-0.4178	No
46	NCBP1	Ncbp1			10081	-0.336	-0.4214	No
47	PQBP1	Pqbp1			10115	-0.344	-0.4194	No
48	SART1	Sart1			10213	-0.365	-0.4213	No
49	CDC5L	Cdc5l			10275	-0.375	-0.4207	No
50	CDC40	Cdc40			10351	-0.387	-0.4208	No
51	PHF5A	Phf5a			10367	-0.389	-0.4171	No
52	CWC15	Cwc15			10445	-0.403	-0.4172	No
53	PRPF40A	Prpf40a			10464	-0.407	-0.4135	No
54	SF3B5	Sf3b5			10555	-0.410	-0.4143	No
55	PPIE	Ppie			10685	-0.424	-0.4175	No
56	SNRNP27	Snrnp27			10724	-0.431	-0.4148	No
57	DDX5	Ddx5			10933	-0.459	-0.4227	Yes
58	ACIN1	Acin1			10962	-0.463	-0.4189	Yes
59	BUD31	Bud31			10963	-0.463	-0.4133	Yes
60	RBM25	Rbm25			11088	-0.481	-0.4155	Yes
61	SNRPD3	Snrpd3			11192	-0.497	-0.4162	Yes
62	HSPA1L	Hspa1l			11233	-0.503	-0.4127	Yes
63	LSM8	Lsm8			11378	-0.532	-0.4156	Yes
64	HNRNPU	Hnrnpu			11522	-0.562	-0.4180	Yes
65	SRSF4	Srsf4			11540	-0.567	-0.4123	Yes
66	ALYREF	4931428L18Rik			11615	-0.581	-0.4100	Yes
67	SNRPG	Snrpg			11620	-0.582	-0.4032	Yes
68	MAGOH	Magoh			11745	-0.605	-0.4039	Yes
69	DHX15	Dhx15			11758	-0.608	-0.3973	Yes
70	ZMAT2	Zmat2			11785	-0.615	-0.3916	Yes
71	PRPF19	Prpf19			12014	-0.670	-0.3983	Yes
72	DDX46	Ddx46			12131	-0.699	-0.3973	Yes
73	SNU13	Snu13			12149	-0.703	-0.3899	Yes
74	EFTUD2	Eftud2			12171	-0.708	-0.3827	Yes
75	SRSF6	Srsf6			12203	-0.713	-0.3760	Yes
76	SF3A3	Sf3a3			12302	-0.740	-0.3734	Yes
77	SNRPB2	Snrpb2			12309	-0.741	-0.3648	Yes
78	HNRNPA3	Gm17190			12413	-0.765	-0.3622	Yes
79	SF3B6	Sf3b6			12520	-0.791	-0.3595	Yes
80	CCDC12	Ccdc12			12596	-0.811	-0.3546	Yes
81	EIF4A3	Eif4a3			12674	-0.828	-0.3495	Yes
82	SRSF9	Srsf9			12780	-0.852	-0.3460	Yes
83	HNRNPM	Hnrnpm			12800	-0.858	-0.3368	Yes
84	PRPF3	Prpf3			12869	-0.879	-0.3306	Yes
85	TCERG1	Tcerg1			12880	-0.883	-0.3205	Yes
86	USP39	Usp39			12898	-0.889	-0.3109	Yes
87	PRPF4	Prpf4			12966	-0.910	-0.3042	Yes
88	LSM7	Lsm7			13079	-0.947	-0.3000	Yes
89	PRPF38A	Prpf38a			13157	-0.973	-0.2932	Yes
90	SNRPD2	Snrpd2			13182	-0.982	-0.2828	Yes
91	LSM4	Lsm4			13295	-1.035	-0.2775	Yes
92	THOC3	Thoc3			13385	-1.070	-0.2703	Yes
93	PRPF31	Prpf31			13617	-1.154	-0.2713	Yes
94	SNRPD1	Snrpd1			13634	-1.159	-0.2583	Yes
95	NCBP2	Ncbp2			13687	-1.181	-0.2474	Yes
96	SRSF10	Srsf10			13784	-1.220	-0.2388	Yes
97	LSM2	Lsm2			13819	-1.237	-0.2260	Yes
98	TRA2A	Tra2a			14015	-1.342	-0.2224	Yes
99	RBMX	Rbmx			14019	-1.346	-0.2063	Yes
100	LSM6	Lsm6			14035	-1.356	-0.1908	Yes
101	SNRPF	Snrpf			14084	-1.387	-0.1771	Yes
102	PPIH	Gm7879			14201	-1.461	-0.1669	Yes
103	SNRNP40	Snrnp40			14249	-1.492	-0.1519	Yes
104	SRSF2	Srsf2			14277	-1.511	-0.1353	Yes
105	HNRNPA1	Hnrnpa1			14286	-1.513	-0.1175	Yes
106	SRSF7	Srsf7			14476	-1.685	-0.1094	Yes
107	LSM5	Lsm5			14501	-1.708	-0.0902	Yes
108	LSM3	Lsm3			14813	-2.023	-0.0859	Yes
109	MAGOHB	Magohb			14823	-2.031	-0.0618	Yes
110	TRA2B	Tra2b			14828	-2.039	-0.0374	Yes
111	SRSF3	Srsf3			14871	-2.098	-0.0147	Yes
112	PPIL1	Ppil1			14923	-2.180	0.0084	Yes
113	SNRPA1	Snrpa1			15089	-2.520	0.0283	Yes

Fig 2: KEGG_SPLICEOSOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_SPLICEOSOME: Random ES distribution   
Gene set null distribution of ES for KEGG_SPLICEOSOME