Details for gene set KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_LG.phenotype.cls#NGP_versus_LG_repos
Phenotype	phenotype.cls#NGP_versus_LG_repos
Upregulated in class	NGP
GeneSet	KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	0.2765091
Normalized Enrichment Score (NES)	1.1353918
Nominal p-value	0.1993865
FDR q-value	0.6675182
FWER p-Value	1.0

Fig 1: Enrichment plot: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CD28	Cd28			45	3.429	0.0427	Yes
2	FOS	Fos			152	2.726	0.0720	Yes
3	LAT	Lat			213	2.533	0.1018	Yes
4	TEC	Tec			424	2.118	0.1164	Yes
5	IKBKG	Ikbkg			478	2.041	0.1401	Yes
6	CBLB	Cblb			600	1.881	0.1572	Yes
7	TNF	Tnf			615	1.864	0.1811	Yes
8	PLCG1	Plcg1			698	1.760	0.1992	Yes
9	NFAT5	Nfat5			701	1.754	0.2224	Yes
10	IL4	Il4			756	1.694	0.2414	Yes
11	PIK3CD	Pik3cd			1218	1.353	0.2295	Yes
12	VAV3	Vav3			1374	1.276	0.2364	Yes
13	CD247	Cd247			1883	1.064	0.2177	Yes
14	ICOS	Icos			2061	0.991	0.2194	Yes
15	MAPK12	Mapk12			2104	0.983	0.2297	Yes
16	NRAS	Nras			2132	0.975	0.2409	Yes
17	CBL	Cbl			2177	0.958	0.2508	Yes
18	DLG1	Dlg1			2424	0.886	0.2466	Yes
19	NCK2	Nck2			2636	0.836	0.2441	Yes
20	CHP2	Chp2			2711	0.819	0.2502	Yes
21	SOS2	Sos2			3239	0.702	0.2254	Yes
22	GRAP2	Grap2			3254	0.699	0.2337	Yes
23	MAPK3	Mapk3			3274	0.697	0.2418	Yes
24	GSK3B	Gsk3b			3289	0.693	0.2501	Yes
25	PAK5	Pak7			3367	0.678	0.2541	Yes
26	CHUK	Chuk			3408	0.666	0.2604	Yes
27	PIK3CA	Pik3ca			3461	0.655	0.2657	Yes
28	LCK	Lck			3532	0.640	0.2697	Yes
29	MAP2K7	Map2k7			3558	0.635	0.2765	Yes
30	IKBKB	Ikbkb			3825	0.572	0.2669	No
31	IL5	Il5			4053	0.531	0.2592	No
32	BCL10	Bcl10			4394	0.475	0.2435	No
33	PRKCQ	Prkcq			4635	0.440	0.2338	No
34	CARD11	Card11			4729	0.428	0.2335	No
35	MAP3K8	Map3k8			4865	0.412	0.2302	No
36	CDK4	Cdk4			4881	0.408	0.2346	No
37	PPP3R2	Ppp3r2			4958	0.401	0.2351	No
38	IL10	Il10			4976	0.401	0.2393	No
39	CTLA4	Ctla4			4998	0.401	0.2432	No
40	CD4	Cd4			5276	0.357	0.2300	No
41	VAV1	Vav1			5304	0.356	0.2330	No
42	MAP2K1	Map2k1			5442	0.350	0.2288	No
43	NFKBIA	Nfkbia			5607	0.322	0.2225	No
44	IL2	Il2			5616	0.320	0.2262	No
45	MALT1	Malt1			6146	0.236	0.1951	No
46	CHP1	Chp1			6216	0.224	0.1936	No
47	RELA	Rela			6219	0.223	0.1964	No
48	PDPK1	Pdpk1			6452	0.184	0.1838	No
49	AKT1	Akt1			6571	0.164	0.1783	No
50	MAP3K7	Map3k7			6762	0.130	0.1678	No
51	AKT2	Akt2			6803	0.125	0.1668	No
52	SOS1	Sos1			6848	0.116	0.1655	No
53	NFATC4	Nfatc4			6926	0.106	0.1619	No
54	PIK3CG	Pik3cg			7113	0.076	0.1509	No
55	PPP3CB	Ppp3cb			8260	-0.059	0.0774	No
56	NCK1	Nck1			8346	-0.073	0.0729	No
57	PAK4	Pak4			8362	-0.075	0.0729	No
58	NFKBIE	Nfkbie			8453	-0.087	0.0682	No
59	NFATC3	Nfatc3			8782	-0.138	0.0488	No
60	ZAP70	Zap70			8932	-0.159	0.0413	No
61	PPP3CA	Ppp3ca			9141	-0.186	0.0302	No
62	CBLC	Cblc			9382	-0.224	0.0177	No
63	NFKBIB	Nfkbib			9549	-0.248	0.0102	No
64	MAPK11	Mapk11			9637	-0.261	0.0081	No
65	RHOA	Rhoa			9715	-0.276	0.0067	No
66	PAK2	Pak2			9784	-0.286	0.0061	No
67	AKT3	Akt3			9809	-0.291	0.0084	No
68	VAV2	Vav2			9900	-0.308	0.0067	No
69	CDC42	Cdc42			10548	-0.409	-0.0298	No
70	NFATC1	Nfatc1			10715	-0.429	-0.0348	No
71	MAPK1	Mapk1			10902	-0.453	-0.0409	No
72	CSF2	Csf2			10999	-0.469	-0.0409	No
73	FYN	Fyn			11465	-0.549	-0.0637	No
74	GRB2	Grb2			11488	-0.555	-0.0577	No
75	PIK3R5	Pik3r5			11573	-0.572	-0.0556	No
76	ITK	Itk			11651	-0.589	-0.0527	No
77	PAK1	Pak1			11717	-0.600	-0.0490	No
78	RAF1	Raf1			11747	-0.605	-0.0428	No
79	RASGRP1	Rasgrp1			11804	-0.619	-0.0382	No
80	MAPK9	Mapk9			12013	-0.670	-0.0428	No
81	PTPRC	Ptprc			12305	-0.740	-0.0518	No
82	KRAS	Kras			12675	-0.828	-0.0647	No
83	NFKB1	Nfkb1			12888	-0.885	-0.0667	No
84	MAPK14	Mapk14			13103	-0.956	-0.0678	No
85	PIK3R1	Pik3r1			13222	-1.001	-0.0622	No
86	HRAS	Hras			13248	-1.014	-0.0503	No
87	PTPN6	Ptpn6			13700	-1.188	-0.0637	No
88	PAK3	Pak3			13741	-1.206	-0.0503	No
89	PAK6	Pak6			13766	-1.215	-0.0357	No
90	MAP3K14	Map3k14			13933	-1.303	-0.0291	No
91	PPP3CC	Ppp3cc			14137	-1.416	-0.0234	No
92	PIK3CB	Pik3cb			14292	-1.520	-0.0132	No
93	JUN	Jun			14788	-2.002	-0.0187	No
94	MAPK13	Mapk13			14956	-2.243	0.0003	No
95	NFATC2	Nfatc2			15159	-2.746	0.0237	No

Fig 2: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY