Details for gene set KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_NG.phenotype.cls#NGP_versus_NG_repos
Phenotype	phenotype.cls#NGP_versus_NG_repos
Upregulated in class	NGP
GeneSet	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC
Enrichment Score (ES)	0.32255676
Normalized Enrichment Score (NES)	1.1456864
Nominal p-value	0.21035059
FDR q-value	0.7760984
FWER p-Value	1.0

Fig 1: Enrichment plot: KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CACNA1D	Cacna1d			5	3.519	0.0822	Yes
2	CTNNA2	Ctnna2			42	2.455	0.1375	Yes
3	CACNG7	Cacng7			162	1.757	0.1710	Yes
4	CACNA2D2	Cacna2d2			437	1.215	0.1818	Yes
5	CACNG4	Cacng4			597	1.047	0.1960	Yes
6	ITGB7	Itgb7			697	0.982	0.2127	Yes
7	SLC8A1	Slc8a1			742	0.945	0.2320	Yes
8	ITGA2B	Itga2b			953	0.849	0.2383	Yes
9	CACNG8	Cacng8			1012	0.822	0.2538	Yes
10	ACTG1	Actg1			1080	0.805	0.2684	Yes
11	CACNA2D3	Cacna2d3			1202	0.763	0.2784	Yes
12	CACNG6	Cacng6			1297	0.741	0.2897	Yes
13	ACTB	Actb			1313	0.740	0.3061	Yes
14	ITGA9	Itga9			1524	0.669	0.3082	Yes
15	CTNNA3	Ctnna3			1544	0.663	0.3226	Yes
16	DSC2	Dsc2			2426	0.473	0.2767	No
17	TCF7L1	Tcf7l1			2560	0.450	0.2786	No
18	GJA1	Gja6			2598	0.446	0.2867	No
19	CACNB3	Cacnb3			2881	0.418	0.2782	No
20	CACNB1	Cacnb1			3178	0.388	0.2682	No
21	RYR2	Ryr2			3306	0.368	0.2686	No
22	CDH2	Cdh2			3343	0.362	0.2748	No
23	EMD	Emd			3355	0.360	0.2825	No
24	ITGA3	Itga3			3869	0.310	0.2566	No
25	PKP2	Pkp2			4605	0.227	0.2143	No
26	LEF1	Lef1			4943	0.195	0.1971	No
27	ACTN1	Actn1			5225	0.170	0.1829	No
28	CTNNB1	Ctnnb1			5547	0.143	0.1655	No
29	LAMA2	Lama2			6157	0.094	0.1283	No
30	SGCB	Sgcb			6279	0.085	0.1225	No
31	ITGA5	Itga5			6290	0.084	0.1238	No
32	SGCA	Sgca			6299	0.084	0.1253	No
33	SGCG	Sgcg			6491	0.071	0.1146	No
34	CACNG3	Cacng3			7645	0.000	0.0400	No
35	CACNG5	Cacng5			7646	0.000	0.0400	No
36	ACTN4	Actn4			8219	-0.025	0.0036	No
37	ATP2A2	Atp2a2			8419	-0.038	-0.0084	No
38	CTNNA1	Ctnna1			8624	-0.052	-0.0204	No
39	LMNA	Lmna			8874	-0.070	-0.0348	No
40	ITGB6	Itgb6			10249	-0.172	-0.1197	No
41	ITGB5	Itgb5			10790	-0.214	-0.1496	No
42	ITGA10	Gm42957			10991	-0.232	-0.1571	No
43	CACNB2	Cacnb2			11382	-0.270	-0.1760	No
44	JUP	Jup			11408	-0.273	-0.1712	No
45	ACTN3	Actn3			11480	-0.279	-0.1693	No
46	CACNA2D1	Cacna2d1			11528	-0.283	-0.1657	No
47	ITGB1	Itgb1			11611	-0.292	-0.1641	No
48	TCF7	Tcf7			11844	-0.317	-0.1717	No
49	CACNA1F	Cacna1f			12021	-0.338	-0.1752	No
50	ITGA6	Itga6			12220	-0.357	-0.1796	No
51	TCF7L2	Tcf7l2			12621	-0.404	-0.1960	No
52	ACTN2	Actn2			13212	-0.478	-0.2230	No
53	CACNG2	Cacng2			13384	-0.501	-0.2223	No
54	CACNA2D4	Cacna2d4			13536	-0.524	-0.2197	No
55	CACNA1C	Cacna1c			13597	-0.532	-0.2111	No
56	DMD	Dmd			13692	-0.551	-0.2043	No
57	ITGA8	Itga8			14006	-0.615	-0.2101	No
58	DAG1	Dag1			14182	-0.657	-0.2060	No
59	ITGB4	Itgb4			14189	-0.658	-0.1910	No
60	ITGAV	Itgav			14285	-0.689	-0.1810	No
61	DES	Des			14489	-0.757	-0.1764	No
62	ITGA11	Itga11			14522	-0.769	-0.1604	No
63	ITGA1	Itga1			14645	-0.821	-0.1491	No
64	ITGA7	Itga7			15001	-1.007	-0.1484	No
65	ITGB8	Itgb8			15052	-1.054	-0.1269	No
66	ITGA4	Itga4			15139	-1.134	-0.1059	No
67	ITGA2	Itga2			15178	-1.187	-0.0805	No
68	DSP	Dsp			15271	-1.317	-0.0556	No
69	CACNA1S	Cacna1s			15291	-1.364	-0.0248	No
70	SGCD	Sgcd			15427	-1.700	0.0063	No

Fig 2: KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC: Random ES distribution   
Gene set null distribution of ES for KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC