Details for gene set KEGG_CELL_CYCLE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_NG.phenotype.cls#NGP_versus_NG_repos
Phenotype	phenotype.cls#NGP_versus_NG_repos
Upregulated in class	NG
GeneSet	KEGG_CELL_CYCLE
Enrichment Score (ES)	-0.55503106
Normalized Enrichment Score (NES)	-2.2941787
Nominal p-value	0.0
FDR q-value	0.0
FWER p-Value	0.0

Fig 1: Enrichment plot: KEGG_CELL_CYCLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CDKN1C	Cdkn1c			1525	0.668	-0.0865	No
2	MDM2	Mdm2			1689	0.623	-0.0855	No
3	CDK4	Cdk4			2265	0.493	-0.1136	No
4	TGFB2	Tgfb2			2621	0.442	-0.1284	No
5	MCM7	Mcm7			2857	0.420	-0.1358	No
6	WEE2	Wee2			3405	0.356	-0.1647	No
7	CDKN1A	Cdkn1a			3630	0.341	-0.1729	No
8	ORC5	Orc5			3635	0.341	-0.1668	No
9	CDC25A	Cdc25a			3703	0.331	-0.1650	No
10	ORC3	Orc3			3961	0.299	-0.1761	No
11	MAD1L1	Mad1l1			4124	0.279	-0.1814	No
12	ZBTB17	Zbtb17			4168	0.274	-0.1791	No
13	ATR	Atr			4198	0.271	-0.1759	No
14	CCNB3	Ccnb3			4343	0.254	-0.1805	No
15	MYC	Myc			4500	0.237	-0.1862	No
16	PRKDC	Prkdc			4717	0.216	-0.1962	No
17	E2F3	E2f3			4778	0.209	-0.1962	No
18	TP53	Trp53			4907	0.199	-0.2008	No
19	ABL1	Abl1			5035	0.187	-0.2056	No
20	SMAD4	Smad4			5051	0.185	-0.2031	No
21	HDAC2	Hdac2			5129	0.179	-0.2048	No
22	ANAPC2	Anapc2			5216	0.171	-0.2072	No
23	SFN	Sfn			5260	0.167	-0.2068	No
24	CDC26	Cdc26			5398	0.156	-0.2128	No
25	ATM	Atm			5515	0.145	-0.2176	No
26	RB1	Rb1			5556	0.143	-0.2176	No
27	SKP2	Skp2			5702	0.131	-0.2246	No
28	E2F5	E2f5			5817	0.121	-0.2297	No
29	CDK7	Cdk7			5960	0.110	-0.2369	No
30	EP300	Ep300			5976	0.109	-0.2358	No
31	CDC16	Cdc16			6103	0.099	-0.2421	No
32	E2F4	E2f4			6131	0.096	-0.2421	No
33	RBX1	Rbx1			6414	0.077	-0.2590	No
34	SMAD3	Smad3			6415	0.077	-0.2576	No
35	ANAPC4	Anapc4			6445	0.075	-0.2580	No
36	MAD2L2	Mad2l2			6585	0.065	-0.2659	No
37	CDC25B	Cdc25b			6635	0.062	-0.2679	No
38	GADD45B	Gadd45b			6667	0.059	-0.2688	No
39	SMC1B	Smc1b			6730	0.054	-0.2718	No
40	SKP1	Skp1a			6868	0.043	-0.2799	No
41	ANAPC5	Anapc5			6928	0.039	-0.2830	No
42	BUB3	Bub3			7242	0.016	-0.3030	No
43	ORC2	Orc2			7408	0.004	-0.3136	No
44	CDKN2C	Cdkn2c			7899	-0.003	-0.3454	No
45	ANAPC10	Anapc10			8032	-0.012	-0.3537	No
46	ORC4	Orc4			8259	-0.028	-0.3679	No
47	YWHAE	Ywhae			8296	-0.031	-0.3696	No
48	SMC1A	Smc1a			8464	-0.041	-0.3797	No
49	YWHAQ	Ywhaq			8484	-0.043	-0.3801	No
50	ANAPC1	Anapc1			8693	-0.058	-0.3926	No
51	ANAPC7	Anapc7			8744	-0.061	-0.3947	No
52	CCNH	Ccnh			9107	-0.087	-0.4165	No
53	GADD45A	Gadd45a			9434	-0.110	-0.4356	No
54	CCND3	Ccnd3			9564	-0.120	-0.4418	No
55	RAD21	Rad21			9655	-0.128	-0.4452	No
56	SMAD2	Smad2			9721	-0.132	-0.4470	No
57	CUL1	Cul1			9964	-0.152	-0.4599	No
58	CREBBP	Crebbp			9980	-0.152	-0.4580	No
59	DBF4	Dbf4			10287	-0.175	-0.4746	No
60	GSK3B	Gsk3b			10504	-0.192	-0.4850	No
61	FZR1	Fzr1			10507	-0.192	-0.4816	No
62	TFDP2	Tfdp2			10681	-0.205	-0.4890	No
63	RBL2	Rbl2			10696	-0.206	-0.4861	No
64	SMC3	Smc3			10718	-0.208	-0.4835	No
65	MCM2	Mcm2			10802	-0.215	-0.4849	No
66	YWHAG	Ywhag			10830	-0.218	-0.4826	No
67	TFDP1	Tfdp1			10866	-0.220	-0.4808	No
68	CDC27	Cdc27			10918	-0.225	-0.4799	No
69	PCNA	Pcna			11055	-0.238	-0.4843	No
70	STAG2	Stag2			11196	-0.252	-0.4887	No
71	E2F1	E2f1			11282	-0.260	-0.4894	No
72	ORC6	Orc6			11802	-0.311	-0.5172	No
73	CDC14A	Cdc14a			11838	-0.316	-0.5136	No
74	E2F2	E2f2			11841	-0.317	-0.5078	No
75	STAG1	Stag1			11973	-0.332	-0.5102	No
76	YWHAB	Ywhab			12014	-0.337	-0.5065	No
77	CDC23	Cdc23			12078	-0.344	-0.5042	No
78	YWHAZ	Ywhaz			12235	-0.358	-0.5076	No
79	CHEK2	Chek2			12702	-0.416	-0.5301	No
80	HDAC1	Hdac1			12724	-0.420	-0.5236	No
81	TGFB1	Tgfb1			12771	-0.426	-0.5187	No
82	RBL1	Rbl1			13007	-0.448	-0.5256	No
83	YWHAH	Ywhah			13149	-0.468	-0.5260	No
84	ANAPC13	Anapc13			13302	-0.496	-0.5266	No
85	CDK2	Cdk2			13529	-0.524	-0.5315	No
86	CCNE1	Ccne1			13892	-0.591	-0.5440	Yes
87	MAD2L1	Mad2l1			14001	-0.614	-0.5396	Yes
88	CHEK1	Chek1			14031	-0.620	-0.5299	Yes
89	GADD45G	Gadd45g			14062	-0.627	-0.5202	Yes
90	CDKN2D	Cdkn2d			14151	-0.649	-0.5138	Yes
91	CCNA1	Ccna1			14156	-0.651	-0.5019	Yes
92	CDKN1B	Cdkn1b			14187	-0.658	-0.4916	Yes
93	MCM6	Mcm6			14196	-0.661	-0.4798	Yes
94	CCNE2	Ccne2			14309	-0.696	-0.4741	Yes
95	PKMYT1	Pkmyt1			14359	-0.714	-0.4640	Yes
96	CDC7	Cdc7			14384	-0.721	-0.4521	Yes
97	CDK1	Cdk1			14397	-0.727	-0.4393	Yes
98	MCM4	Mcm4			14554	-0.779	-0.4349	Yes
99	ORC1	Orc1			14582	-0.790	-0.4220	Yes
100	CDK6	Cdk6			14796	-0.885	-0.4193	Yes
101	MCM3	Mcm3			14865	-0.927	-0.4064	Yes
102	CCND1	Ccnd1			14921	-0.960	-0.3921	Yes
103	WEE1	Wee1			14965	-0.985	-0.3766	Yes
104	MCM5	Mcm5			15094	-1.089	-0.3646	Yes
105	CDC20	Cdc20			15097	-1.097	-0.3443	Yes
106	TGFB3	Tgfb3			15310	-1.400	-0.3320	Yes
107	CDC45	Cdc45			15327	-1.438	-0.3062	Yes
108	CDC25C	Cdc25c			15401	-1.621	-0.2807	Yes
109	ESPL1	Espl1			15422	-1.681	-0.2507	Yes
110	TTK	Ttk			15429	-1.705	-0.2193	Yes
111	CDC6	Cdc6			15430	-1.707	-0.1875	Yes
112	PLK1	Plk1			15467	-1.900	-0.1545	Yes
113	CCNB2	Ccnb2			15470	-1.905	-0.1191	Yes
114	BUB1	Bub1			15485	-2.064	-0.0815	Yes
115	CCNB1	Ccnb1			15492	-2.124	-0.0424	Yes
116	CCNA2	Ccna2			15511	-2.386	0.0009	Yes

Fig 2: KEGG_CELL_CYCLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_CELL_CYCLE: Random ES distribution   
Gene set null distribution of ES for KEGG_CELL_CYCLE