Details for gene set KEGG_FOCAL

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_NG.phenotype.cls#NGP_versus_NG_repos
Phenotype	phenotype.cls#NGP_versus_NG_repos
Upregulated in class	NG
GeneSet	KEGG_FOCAL_ADHESION
Enrichment Score (ES)	-0.3705011
Normalized Enrichment Score (NES)	-1.6393081
Nominal p-value	0.0
FDR q-value	0.07905926
FWER p-Value	0.425

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COMP	Comp	317	1.391	-0.0042	No
2	PIK3CD	Pik3cd	423	1.233	0.0035	No
3	ITGB7	Itgb7	697	0.982	-0.0027	No
4	ZYX	Zyx	817	0.904	0.0003	No
5	KDR	Kdr	927	0.859	0.0033	No
6	SHC3	Shc3	945	0.853	0.0123	No
7	ITGA2B	Itga2b	953	0.849	0.0219	No
8	ACTG1	Actg1	1080	0.805	0.0232	No
9	BCAR1	Bcar1	1232	0.750	0.0222	No
10	ACTB	Actb	1313	0.740	0.0258	No
11	THBS1	Thbs1	1423	0.703	0.0270	No
12	PAK5	Pak7	1494	0.678	0.0304	No
13	ITGA9	Itga9	1524	0.669	0.0364	No
14	ILK	Ilk	1702	0.620	0.0322	No
15	PARVG	Parvg	1846	0.574	0.0297	No
16	PDGFRA	Pdgfra	1936	0.552	0.0304	No
17	PRKCG	Prkcg	1985	0.540	0.0337	No
18	LAMC3	Lamc3	2124	0.517	0.0308	No
19	COL11A2	Col11a2	2163	0.509	0.0343	No
20	LAMB1	Lamb1	2243	0.497	0.0350	No
21	VAV3	Vav3	2527	0.457	0.0220	No
22	COL6A6	Col6a6	2659	0.440	0.0187	No
23	RELN	Reln	2836	0.424	0.0122	No
24	VCL	Vcl	2874	0.419	0.0147	No
25	VTN	Vtn	3047	0.401	0.0083	No
26	MYL2	Myl2	3055	0.401	0.0125	No
27	TNXB	Tnxb	3243	0.378	0.0048	No
28	VAV1	Vav1	3402	0.356	-0.0013	No
29	IBSP	Ibsp	3434	0.356	0.0009	No
30	MYL10	Myl10	3527	0.356	-0.0009	No
31	RAC2	Rac2	3662	0.338	-0.0056	No
32	FLNA	Flna	3855	0.312	-0.0145	No
33	ITGA3	Itga3	3869	0.310	-0.0116	No
34	PGF	Pgf	4268	0.263	-0.0345	No
35	MYLK2	Mylk2	4632	0.225	-0.0555	No
36	VASP	Vasp	4673	0.220	-0.0555	No
37	VAV2	Vav2	4685	0.219	-0.0536	No
38	MAPK8	Mapk8	4781	0.209	-0.0574	No
39	VEGFB	Vegfb	4822	0.206	-0.0575	No
40	ERBB2	Erbb2	4924	0.197	-0.0618	No
41	PAK4	Pak4	5123	0.179	-0.0726	No
42	VWF	Vwf	5203	0.173	-0.0757	No
43	ACTN1	Actn1	5225	0.170	-0.0750	No
44	TNN	Tnn	5426	0.154	-0.0863	No
45	CTNNB1	Ctnnb1	5547	0.143	-0.0924	No
46	MAPK3	Mapk3	5579	0.140	-0.0928	No
47	LAMA1	Lama1	5640	0.135	-0.0951	No
48	MYL9	Myl9	5705	0.130	-0.0977	No
49	PDGFC	Pdgfc	5812	0.121	-0.1032	No
50	PARVB	Parvb	5894	0.116	-0.1071	No
51	AKT1	Akt1	6108	0.098	-0.1198	No
52	LAMA2	Lama2	6157	0.094	-0.1218	No
53	ITGA5	Itga5	6290	0.084	-0.1295	No
54	AKT2	Akt2	6509	0.070	-0.1428	No
55	XIAP	Xiap	6636	0.061	-0.1503	No
56	COL2A1	Col2a1	6640	0.061	-0.1498	No
57	ARHGAP35	Arhgap35	6771	0.051	-0.1577	No
58	PAK6	Pak6	6781	0.050	-0.1577	No
59	PAK1	Pak1	6823	0.047	-0.1598	No
60	SRC	Src	6873	0.043	-0.1625	No
61	BIRC2	Birc2	7012	0.033	-0.1711	No
62	LAMB2	Lamb2	7217	0.018	-0.1842	No
63	MYLPF	Mylpf	7248	0.015	-0.1860	No
64	FLNC	Flnc	7975	-0.008	-0.2332	No
65	EGF	Egf	7992	-0.009	-0.2342	No
66	PPP1CC	Ppp1cc	8181	-0.023	-0.2461	No
67	ACTN4	Actn4	8219	-0.025	-0.2483	No
68	PIK3CA	Pik3ca	8340	-0.034	-0.2557	No
69	SOS1	Sos1	8438	-0.040	-0.2615	No
70	PTK2	Ptk2	8469	-0.041	-0.2630	No
71	CAV3	Cav3	8939	-0.075	-0.2927	No
72	CRKL	Crkl	9039	-0.082	-0.2982	No
73	MAPK9	Mapk9	9049	-0.083	-0.2978	No
74	SOS2	Sos2	9062	-0.084	-0.2976	No
75	PPP1R12A	Ppp1r12a	9228	-0.094	-0.3072	No
76	RAP1A	Rap1a	9366	-0.105	-0.3149	No
77	PXN	Pxn	9450	-0.111	-0.3190	No
78	HGF	Hgf	9454	-0.111	-0.3179	No
79	PIP5K1C	Pip5k1c	9486	-0.113	-0.3186	No
80	RAF1	Raf1	9494	-0.114	-0.3177	No
81	MYL12A	Myl12a	9495	-0.114	-0.3164	No
82	GRB2	Grb2	9534	-0.118	-0.3174	No
83	CCND3	Ccnd3	9564	-0.120	-0.3179	No
84	VEGFC	Vegfc	9604	-0.123	-0.3190	No
85	RAPGEF1	Rapgef1	9753	-0.135	-0.3271	No
86	COL4A6	Col4a6	9840	-0.142	-0.3310	No
87	IGF1	Igf1	9853	-0.143	-0.3301	No
88	CAPN2	Capn2	9901	-0.147	-0.3314	No
89	IGF1R	Igf1r	10217	-0.170	-0.3499	No
90	ITGB6	Itgb6	10249	-0.172	-0.3499	No
91	FYN	Fyn	10250	-0.172	-0.3479	No
92	LAMC1	Lamc1	10281	-0.175	-0.3478	No
93	PAK2	Pak2	10297	-0.177	-0.3467	No
94	PPP1CB	Ppp1cb	10473	-0.190	-0.3558	No
95	GSK3B	Gsk3b	10504	-0.192	-0.3555	No
96	MAP2K1	Map2k1	10546	-0.196	-0.3559	No
97	PPP1CA	Ppp1ca	10577	-0.198	-0.3555	No
98	ROCK2	Rock2	10619	-0.200	-0.3558	No
99	MAPK1	Mapk1	10708	-0.207	-0.3591	No
100	CRK	Crk	10736	-0.210	-0.3584	No
101	ITGB5	Itgb5	10790	-0.214	-0.3593	No
102	MAPK10	Mapk10	10797	-0.215	-0.3572	No
103	PIK3CG	Pik3cg	10818	-0.216	-0.3559	No
104	PDPK1	Pdpk1	10897	-0.223	-0.3584	No
105	ITGA10	Gm42957	10991	-0.232	-0.3617	No
106	TLN1	Tln1	11050	-0.238	-0.3626	No
107	SHC4	Shc4	11135	-0.246	-0.3652	No
108	FLNB	Flnb	11217	-0.254	-0.3675	Yes
109	AKT3	Akt3	11260	-0.258	-0.3672	Yes
110	FN1	Fn1	11306	-0.262	-0.3670	Yes
111	JUN	Jun	11324	-0.264	-0.3650	Yes
112	EGFR	Egfr	11360	-0.268	-0.3641	Yes
113	DIAPH1	Diaph1	11370	-0.269	-0.3615	Yes
114	SPP1	Spp1	11427	-0.274	-0.3619	Yes
115	CHAD	Chad	11439	-0.275	-0.3594	Yes
116	MYL7	Myl7	11466	-0.277	-0.3578	Yes
117	ACTN3	Actn3	11480	-0.279	-0.3553	Yes
118	PDGFA	Pdgfa	11487	-0.280	-0.3524	Yes
119	PTEN	Pten	11511	-0.282	-0.3506	Yes
120	ITGB1	Itgb1	11611	-0.292	-0.3536	Yes
121	BIRC3	Birc3	11686	-0.300	-0.3549	Yes
122	MET	Met	11695	-0.300	-0.3518	Yes
123	ROCK1	Rock1	11801	-0.311	-0.3550	Yes
124	COL4A1	Col4a1	11819	-0.313	-0.3524	Yes
125	CDC42	Cdc42	11896	-0.324	-0.3535	Yes
126	MYLK3	Mylk3	11899	-0.324	-0.3498	Yes
127	TLN2	Tln2	11940	-0.328	-0.3486	Yes
128	BCL2	Bcl2	12075	-0.344	-0.3532	Yes
129	BRAF	Braf	12139	-0.348	-0.3532	Yes
130	RHOA	Rhoa	12195	-0.354	-0.3526	Yes
131	ITGA6	Itga6	12220	-0.357	-0.3500	Yes
132	HRAS	Hras	12233	-0.358	-0.3465	Yes
133	BAD	Bad	12251	-0.360	-0.3434	Yes
134	PARVA	Parva	12373	-0.374	-0.3468	Yes
135	RAC1	Rac1	12380	-0.375	-0.3428	Yes
136	SHC1	Shc1	12435	-0.383	-0.3418	Yes
137	LAMC2	Lamc2	12467	-0.387	-0.3392	Yes
138	RAP1B	Rap1b	12581	-0.401	-0.3419	Yes
139	ELK1	Elk1	12586	-0.401	-0.3374	Yes
140	PIK3R5	Pik3r5	12592	-0.402	-0.3330	Yes
141	COL4A2	Col4a2	12687	-0.414	-0.3342	Yes
142	PRKCA	Prkca	12751	-0.423	-0.3333	Yes
143	DOCK1	Dock1	12778	-0.426	-0.3300	Yes
144	PIK3R1	Pik3r1	12996	-0.447	-0.3388	Yes
145	MYL12B	Myl12b	13167	-0.472	-0.3443	Yes
146	ACTN2	Actn2	13212	-0.478	-0.3415	Yes
147	LAMA4	Lama4	13247	-0.484	-0.3380	Yes
148	MYLK	Mylk	13274	-0.491	-0.3339	Yes
149	RAC3	Rac3	13294	-0.495	-0.3293	Yes
150	VEGFD	Vegfd	13416	-0.504	-0.3312	Yes
151	VEGFA	Vegfa	13510	-0.521	-0.3311	Yes
152	PAK3	Pak3	13553	-0.527	-0.3277	Yes
153	COL11A1	Col11a1	13641	-0.540	-0.3269	Yes
154	CAV1	Cav1	13720	-0.556	-0.3255	Yes
155	PDGFRB	Pdgfrb	13723	-0.557	-0.3190	Yes
156	ARHGAP5	Arhgap5	13738	-0.561	-0.3133	Yes
157	COL6A1	Col6a1	13839	-0.580	-0.3130	Yes
158	LAMA5	Lama5	13933	-0.600	-0.3119	Yes
159	COL6A3	Col6a3	13951	-0.603	-0.3059	Yes
160	PRKCB	Prkcb	13958	-0.605	-0.2991	Yes
161	TNR	Tnr	13971	-0.608	-0.2927	Yes
162	ITGA8	Itga8	14006	-0.615	-0.2877	Yes
163	THBS3	Thbs3	14080	-0.632	-0.2850	Yes
164	RASGRF1	Rasgrf1	14108	-0.639	-0.2792	Yes
165	ITGB4	Itgb4	14189	-0.658	-0.2766	Yes
166	ITGAV	Itgav	14285	-0.689	-0.2746	Yes
167	TNC	Tnc	14428	-0.735	-0.2752	Yes
168	ITGA11	Itga11	14522	-0.769	-0.2722	Yes
169	COL1A2	Col1a2	14592	-0.795	-0.2673	Yes
170	ITGA1	Itga1	14645	-0.821	-0.2610	Yes
171	PDGFB	Pdgfb	14669	-0.829	-0.2527	Yes
172	COL6A2	Col6a2	14684	-0.839	-0.2437	Yes
173	CAV2	Cav2	14721	-0.854	-0.2359	Yes
174	FLT1	Flt1	14807	-0.893	-0.2309	Yes
175	COL5A2	Col5a2	14890	-0.944	-0.2251	Yes
176	CCND1	Ccnd1	14921	-0.960	-0.2157	Yes
177	COL3A1	Col3a1	14977	-0.993	-0.2075	Yes
178	ITGA7	Itga7	15001	-1.007	-0.1971	Yes
179	ITGB8	Itgb8	15052	-1.054	-0.1879	Yes
180	LAMA3	Lama3	15079	-1.075	-0.1769	Yes
181	ITGA4	Itga4	15139	-1.134	-0.1673	Yes
182	LAMB3	Lamb3	15148	-1.149	-0.1542	Yes
183	COL5A1	Col5a1	15174	-1.182	-0.1419	Yes
184	ITGA2	Itga2	15178	-1.187	-0.1281	Yes
185	THBS4	Thbs4	15245	-1.275	-0.1173	Yes
186	THBS2	Thbs2	15251	-1.286	-0.1024	Yes
187	PIK3CB	Pik3cb	15260	-1.300	-0.0875	Yes
188	COL5A3	Col5a3	15370	-1.534	-0.0765	Yes
189	FLT4	Flt4	15375	-1.541	-0.0586	Yes
190	COL4A4	Col4a4	15411	-1.647	-0.0414	Yes
191	COL1A1	Col1a1	15434	-1.720	-0.0224	Yes
192	PDGFD	Pdgfd	15513	-2.394	0.0008	Yes