Details for gene set KEGG_PARKINSONS_DISEASE[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_NG.phenotype.cls#NGP_versus_NG_repos
Phenotype	phenotype.cls#NGP_versus_NG_repos
Upregulated in class	NG
GeneSet	KEGG_PARKINSONS_DISEASE
Enrichment Score (ES)	-0.40436158
Normalized Enrichment Score (NES)	-1.6546981
Nominal p-value	0.0
FDR q-value	0.0749144
FWER p-Value	0.377

Fig 1: Enrichment plot: KEGG_PARKINSONS_DISEASE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SNCAIP	Sncaip			753	0.941	-0.0229	No
2	SLC25A31	Slc25a31			766	0.933	0.0021	No
3	COX6B2	Cox6b2			984	0.837	0.0112	No
4	COX8C	Cox8b			1280	0.741	0.0125	No
5	COX4I2	Cox4i2			1333	0.734	0.0294	No
6	SLC25A5	Slc25a5			2270	0.493	-0.0177	No
7	SLC6A3	Slc6a3			3504	0.356	-0.0878	No
8	MT-ND4L	mt-Nd4l			3514	0.356	-0.0785	No
9	PRKN	Prkn			3900	0.306	-0.0951	No
10	PPID	Ppid			4439	0.244	-0.1232	No
11	NDUFA6	Ndufa6			5344	0.161	-0.1774	No
12	UQCRFS1	Uqcrfs1			5418	0.155	-0.1779	No
13	UBA1	Uba1			5474	0.149	-0.1773	No
14	UBE2J2	Ube2j2			5592	0.139	-0.1811	No
15	NDUFB2	Ndufb2			5696	0.131	-0.1841	No
16	NDUFA10	Ndufa10			5721	0.129	-0.1821	No
17	CYC1	Cyc1			5740	0.126	-0.1798	No
18	SLC18A2	Slc18a2			5750	0.125	-0.1769	No
19	NDUFV1	Ndufv1			5870	0.117	-0.1814	No
20	CASP3	Casp3			6007	0.107	-0.1873	No
21	APAF1	Apaf1			6075	0.101	-0.1888	No
22	UBB	Ubb			6088	0.100	-0.1868	No
23	NDUFS3	Ndufs3			6158	0.093	-0.1887	No
24	COX7A2L	Cox7a2l			6167	0.093	-0.1867	No
25	NDUFB5	Ndufb5			6335	0.082	-0.1952	No
26	CYCS	Cycs			7103	0.027	-0.2443	No
27	NDUFS2	Ndufs2			7378	0.006	-0.2619	No
28	UQCRC2	Uqcrc2			7439	0.002	-0.2657	No
29	TH	Th			7493	0.000	-0.2692	No
30	COX7B2	Cox7b2			7652	0.000	-0.2794	No
31	MT-CO2	mt-Co2			7705	0.000	-0.2828	No
32	NDUFA4L2	Ndufa4l2			8009	-0.011	-0.3021	No
33	NDUFS7	Ndufs7			8011	-0.011	-0.3019	No
34	ATP5F1C	Atp5c1			8083	-0.016	-0.3061	No
35	SLC25A4	Slc25a4			8214	-0.025	-0.3138	No
36	COX6A2	Cox6a2			8390	-0.037	-0.3241	No
37	ATP5F1B	Atp5b			8399	-0.037	-0.3236	No
38	NDUFB9	Ndufb9			8817	-0.066	-0.3488	No
39	NDUFAB1	Ndufab1			9031	-0.081	-0.3604	No
40	NDUFA9	Ndufa9			9127	-0.088	-0.3641	No
41	VDAC1	Vdac1			9299	-0.099	-0.3725	No
42	NDUFS4	Ndufs4			9344	-0.103	-0.3725	No
43	COX5B	Cox5b			9355	-0.103	-0.3703	No
44	SDHC	Sdhc			9435	-0.110	-0.3724	No
45	COX4I1	Cox4i1			9535	-0.118	-0.3755	No
46	SNCA	Snca			9568	-0.120	-0.3743	No
47	ATP5F1A	Atp5a1			9760	-0.135	-0.3830	No
48	VDAC3	Vdac3			9787	-0.138	-0.3808	No
49	COX7C	Cox7c			9876	-0.145	-0.3825	No
50	NDUFS1	Ndufs1			9952	-0.151	-0.3832	No
51	COX6B1	Cox6b1			10014	-0.155	-0.3829	No
52	NDUFV2	Ndufv2			10048	-0.157	-0.3807	No
53	HTRA2	Htra2			10049	-0.157	-0.3764	No
54	UBE2J1	Ube2j1			10179	-0.167	-0.3801	No
55	MT-ND4	mt-Nd4			10184	-0.167	-0.3758	No
56	SDHB	Sdhb			10474	-0.190	-0.3893	No
57	CASP9	Casp9			10476	-0.190	-0.3841	No
58	VDAC2	Vdac2			10516	-0.193	-0.3813	No
59	NDUFB10	Ndufb10			10571	-0.197	-0.3793	No
60	NDUFB3	Ndufb3			10631	-0.200	-0.3776	No
61	NDUFA8	Ndufa8			10676	-0.204	-0.3748	No
62	COX5A	Cox5a			10781	-0.213	-0.3757	No
63	COX7A2	Cox7a2			11224	-0.255	-0.3973	Yes
64	UBE2G2	Ube2g2			11245	-0.257	-0.3915	Yes
65	MT-CYB	mt-Cytb			11374	-0.270	-0.3924	Yes
66	UQCRC1	Uqcrc1			11468	-0.278	-0.3907	Yes
67	UBE2G1	Ube2g1			11525	-0.283	-0.3865	Yes
68	MT-ND6	mt-Nd6			11587	-0.289	-0.3825	Yes
69	NDUFB1	Ndufb1-ps			11756	-0.306	-0.3849	Yes
70	COX8A	Cox8a			11885	-0.321	-0.3844	Yes
71	UQCRB	Uqcrb			11992	-0.334	-0.3820	Yes
72	PINK1	Pink1			12112	-0.345	-0.3802	Yes
73	PARK7	Park7			12255	-0.361	-0.3794	Yes
74	ATP5MC3	Atp5g3			12291	-0.365	-0.3716	Yes
75	NDUFB6	Ndufb6			12354	-0.372	-0.3653	Yes
76	NDUFA3	Ndufa3			12359	-0.373	-0.3553	Yes
77	ATP5F1D	Atp5d			12403	-0.379	-0.3476	Yes
78	MT-ND2	mt-Nd2			12428	-0.382	-0.3386	Yes
79	ATP5PD	Atp5h			12479	-0.388	-0.3311	Yes
80	COX7B	Cox7b			12512	-0.392	-0.3224	Yes
81	COX7A1	Cox7a1			12522	-0.394	-0.3121	Yes
82	MT-CO1	mt-Co1			12585	-0.401	-0.3050	Yes
83	MT-ND5	mt-Nd5			12840	-0.436	-0.3094	Yes
84	MT-ATP6	mt-Atp6			12940	-0.443	-0.3036	Yes
85	UCHL1	Uchl1			13080	-0.458	-0.3000	Yes
86	NDUFB7	Ndufb7			13279	-0.492	-0.2992	Yes
87	MT-CO3	mt-Co3			13320	-0.498	-0.2881	Yes
88	ATP5F1E	Atp5e			13433	-0.508	-0.2813	Yes
89	COX6C	Cox6c			13521	-0.523	-0.2725	Yes
90	NDUFB4	Ndufb4			13601	-0.534	-0.2629	Yes
91	NDUFS8	Ndufs8			13664	-0.545	-0.2518	Yes
92	NDUFA1	Ndufa1			13759	-0.566	-0.2423	Yes
93	ATP5PF	Atp5j			13797	-0.573	-0.2288	Yes
94	NDUFS6	Ndufs6			13984	-0.610	-0.2241	Yes
95	NDUFA2	Ndufa2			14058	-0.626	-0.2115	Yes
96	NDUFV3	Ndufv3			14135	-0.645	-0.1986	Yes
97	MT-ND1	mt-Nd1			14152	-0.649	-0.1817	Yes
98	UQCR10	Uqcr10			14215	-0.666	-0.1673	Yes
99	NDUFA4	Ndufa4			14228	-0.671	-0.1496	Yes
100	COX6A1	Cox6a1			14276	-0.686	-0.1337	Yes
101	UQCRQ	Uqcrq			14286	-0.690	-0.1152	Yes
102	NDUFC1	Ndufc1			14306	-0.695	-0.0972	Yes
103	NDUFA5	Ndufa5			14324	-0.701	-0.0789	Yes
104	LRRK2	Lrrk2			14662	-0.827	-0.0779	Yes
105	NDUFS5	Ndufs5			14975	-0.990	-0.0708	Yes
106	UBA7	Uba7			15125	-1.126	-0.0494	Yes
107	UBE2L6	Ube2l6			15270	-1.316	-0.0223	Yes
108	SLC18A1	Slc18a1			15313	-1.405	0.0138	Yes

Fig 2: KEGG_PARKINSONS_DISEASE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_PARKINSONS_DISEASE: Random ES distribution   
Gene set null distribution of ES for KEGG_PARKINSONS_DISEASE