Details for gene set KEGG_WNT_SIGNALING_PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	preliminary.phenotype.cls#NGP_versus_NG.phenotype.cls#NGP_versus_NG_repos
Phenotype	phenotype.cls#NGP_versus_NG_repos
Upregulated in class	NG
GeneSet	KEGG_WNT_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.35001454
Normalized Enrichment Score (NES)	-1.5041187
Nominal p-value	0.0026809652
FDR q-value	0.14791079
FWER p-Value	0.83

Fig 1: Enrichment plot: KEGG_WNT_SIGNALING_PATHWAY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	WIF1	Wif1			325	1.369	0.0058	No
2	WNT6	Wnt6			350	1.331	0.0305	No
3	CHP2	Chp2			1035	0.819	0.0022	No
4	NKD1	Nkd1			1137	0.786	0.0111	No
5	VANGL2	Vangl2			1362	0.721	0.0108	No
6	WNT11	Wnt11			1556	0.660	0.0113	No
7	FZD3	Fzd3			1677	0.626	0.0158	No
8	WNT1	Wnt1			1769	0.596	0.0216	No
9	PRKCG	Prkcg			1985	0.540	0.0183	No
10	FOSL1	Fosl1			1997	0.539	0.0282	No
11	FZD9	Fzd9			2215	0.500	0.0239	No
12	SFRP5	Sfrp5			2272	0.492	0.0300	No
13	TCF7L1	Tcf7l1			2560	0.450	0.0202	No
14	WNT9B	Wnt9b			3022	0.401	-0.0018	No
15	PPP3R2	Ppp3r2			3033	0.401	0.0054	No
16	WNT3	Wnt3			3360	0.359	-0.0087	No
17	RAC2	Rac2			3662	0.338	-0.0216	No
18	DVL3	Dvl3			3721	0.328	-0.0189	No
19	CSNK2A2	Csnk2a2			4035	0.289	-0.0335	No
20	PORCN	Porcn			4319	0.257	-0.0469	No
21	MYC	Myc			4500	0.237	-0.0539	No
22	AXIN1	Axin1			4555	0.232	-0.0528	No
23	BTRC	Btrc			4669	0.220	-0.0558	No
24	RUVBL1	Ruvbl1			4700	0.217	-0.0535	No
25	MAPK8	Mapk8			4781	0.209	-0.0546	No
26	PRKACB	Prkacb			4785	0.209	-0.0507	No
27	PPP2CB	Ppp2cb			4832	0.205	-0.0496	No
28	TP53	Trp53			4907	0.199	-0.0505	No
29	LEF1	Lef1			4943	0.195	-0.0489	No
30	SMAD4	Smad4			5051	0.185	-0.0522	No
31	PPP2R5D	Ppp2r5d			5058	0.185	-0.0490	No
32	NKD2	Nkd2			5213	0.171	-0.0556	No
33	FRAT2	Frat2			5214	0.171	-0.0522	No
34	SFRP2	Sfrp2			5346	0.160	-0.0576	No
35	CTNNB1	Ctnnb1			5547	0.143	-0.0678	No
36	NLK	Nlk			5957	0.111	-0.0922	No
37	EP300	Ep300			5976	0.109	-0.0912	No
38	CTBP1	Ctbp1			6085	0.101	-0.0962	No
39	CTNNBIP1	Ctnnbip1			6166	0.093	-0.0996	No
40	WNT10A	Wnt10a			6186	0.091	-0.0990	No
41	PLCB3	Plcb3			6255	0.087	-0.1017	No
42	CSNK2B	Csnk2b			6402	0.078	-0.1097	No
43	RBX1	Rbx1			6414	0.077	-0.1089	No
44	SMAD3	Smad3			6415	0.077	-0.1074	No
45	WNT7B	Wnt7b			6455	0.074	-0.1085	No
46	PPP3CC	Ppp3cc			6577	0.065	-0.1150	No
47	PPP2R5C	Ppp2r5c			6579	0.065	-0.1138	No
48	PSEN1	Psen1			6617	0.063	-0.1150	No
49	APC2	Apc2			6705	0.056	-0.1196	No
50	SKP1	Skp1a			6868	0.043	-0.1292	No
51	SENP2	Senp2			6980	0.035	-0.1357	No
52	FBXW11	Fbxw11			7033	0.032	-0.1385	No
53	WNT5B	Wnt5b			7043	0.031	-0.1385	No
54	PPP2R1A	Ppp2r1a			7070	0.029	-0.1396	No
55	FRAT1	Frat1			7071	0.029	-0.1390	No
56	LRP5	Lrp5			7094	0.027	-0.1399	No
57	MMP7	Mmp7			7583	0.000	-0.1716	No
58	WNT3A	Wnt3a			7623	0.000	-0.1742	No
59	SOX17	Sox17			7748	0.000	-0.1822	No
60	CACYBP	Cacybp			8046	-0.014	-0.2013	No
61	MAP3K7	Map3k7			8246	-0.027	-0.2137	No
62	PPP2R1B	Ppp2r1b			8265	-0.028	-0.2143	No
63	CSNK1A1	Csnk1a1			8272	-0.029	-0.2141	No
64	SIAH1	Siah1a			8317	-0.033	-0.2163	No
65	WNT8B	Wnt8b			8451	-0.041	-0.2242	No
66	DVL2	Dvl2			8518	-0.046	-0.2275	No
67	CHD8	Chd8			8683	-0.057	-0.2371	No
68	PPARD	Ppard			8914	-0.073	-0.2506	No
69	MAPK9	Mapk9			9049	-0.083	-0.2577	No
70	PPP2R5E	Ppp2r5e			9342	-0.103	-0.2746	No
71	WNT4	Wnt4			9463	-0.111	-0.2802	No
72	WNT16	Wnt16			9537	-0.118	-0.2826	No
73	CCND3	Ccnd3			9564	-0.120	-0.2820	No
74	CTBP2	Ctbp2			9575	-0.121	-0.2802	No
75	CAMK2G	Camk2g			9587	-0.121	-0.2786	No
76	PLCB4	Plcb4			9624	-0.125	-0.2784	No
77	SMAD2	Smad2			9721	-0.132	-0.2821	No
78	CUL1	Cul1			9964	-0.152	-0.2948	No
79	CREBBP	Crebbp			9980	-0.152	-0.2928	No
80	PPP2CA	Ppp2ca			10147	-0.165	-0.3003	No
81	GSK3B	Gsk3b			10504	-0.192	-0.3197	No
82	NFATC3	Nfatc3			10510	-0.192	-0.3162	No
83	ROCK2	Rock2			10619	-0.200	-0.3193	No
84	NFATC4	Nfatc4			10645	-0.202	-0.3169	No
85	MAPK10	Mapk10			10797	-0.215	-0.3225	No
86	PPP3CB	Ppp3cb			10834	-0.218	-0.3206	No
87	LRP6	Lrp6			10904	-0.223	-0.3207	No
88	APC	Apc			10972	-0.230	-0.3205	No
89	FZD6	Fzd6			11240	-0.257	-0.3328	No
90	DVL1	Dvl1			11277	-0.260	-0.3300	No
91	JUN	Jun			11324	-0.264	-0.3278	No
92	DAAM2	Daam2			11537	-0.284	-0.3360	No
93	WNT9A	Wnt9a			11705	-0.301	-0.3409	No
94	ROCK1	Rock1			11801	-0.311	-0.3409	No
95	TCF7	Tcf7			11844	-0.317	-0.3374	No
96	WNT5A	Wnt5a			12039	-0.341	-0.3433	Yes
97	FZD2	Fzd2			12041	-0.341	-0.3367	Yes
98	RHOA	Rhoa			12195	-0.354	-0.3396	Yes
99	DKK1	Dkk1			12288	-0.365	-0.3384	Yes
100	PPP2R5B	Ppp2r5b			12360	-0.373	-0.3357	Yes
101	RAC1	Rac1			12380	-0.375	-0.3295	Yes
102	PRICKLE2	Prickle2			12474	-0.388	-0.3279	Yes
103	FZD4	Fzd4			12501	-0.391	-0.3219	Yes
104	WNT10B	Wnt10b			12526	-0.394	-0.3157	Yes
105	TCF7L2	Tcf7l2			12621	-0.404	-0.3139	Yes
106	VANGL1	Vangl1			12665	-0.410	-0.3086	Yes
107	PRKCA	Prkca			12751	-0.423	-0.3058	Yes
108	FZD1	Fzd1			12813	-0.432	-0.3012	Yes
109	WNT8A	Wnt8a			12875	-0.438	-0.2966	Yes
110	PRKACA	Prkaca			13065	-0.456	-0.2999	Yes
111	NFAT5	Nfat5			13098	-0.460	-0.2929	Yes
112	PPP3CA	Ppp3ca			13145	-0.468	-0.2867	Yes
113	SFRP4	Sfrp4			13160	-0.471	-0.2783	Yes
114	NFATC1	Nfatc1			13225	-0.480	-0.2730	Yes
115	RAC3	Rac3			13294	-0.495	-0.2677	Yes
116	FZD8	Fzd8			13528	-0.523	-0.2725	Yes
117	TBL1XR1	Tbl1xr1			13617	-0.535	-0.2677	Yes
118	CXXC4	Cxxc4			13669	-0.546	-0.2602	Yes
119	NFATC2	Nfatc2			13711	-0.555	-0.2520	Yes
120	SFRP1	Sfrp1			13949	-0.603	-0.2555	Yes
121	CHP1	Chp1			13957	-0.605	-0.2440	Yes
122	PRKCB	Prkcb			13958	-0.605	-0.2321	Yes
123	WNT2B	Wnt2b			13977	-0.609	-0.2213	Yes
124	FZD7	Fzd7			14004	-0.614	-0.2109	Yes
125	PPP2R5A	Ppp2r5a			14284	-0.689	-0.2154	Yes
126	CAMK2B	Camk2b			14425	-0.735	-0.2100	Yes
127	DAAM1	Daam1			14445	-0.743	-0.1966	Yes
128	FZD5	Fzd5			14666	-0.828	-0.1946	Yes
129	FZD10	Fzd10			14685	-0.842	-0.1792	Yes
130	WNT7A	Wnt7a			14879	-0.933	-0.1733	Yes
131	CCND1	Ccnd1			14921	-0.960	-0.1571	Yes
132	PLCB1	Plcb1			15093	-1.088	-0.1468	Yes
133	PLCB2	Plcb2			15231	-1.247	-0.1311	Yes
134	WNT2	Wnt2			15256	-1.292	-0.1072	Yes
135	CAMK2A	Camk2a			15284	-1.351	-0.0824	Yes
136	PRICKLE1	Prickle1			15307	-1.389	-0.0564	Yes
137	DKK2	Dkk2			15382	-1.564	-0.0304	Yes
138	AXIN2	Axin2			15479	-2.011	0.0030	Yes

Fig 2: KEGG_WNT_SIGNALING_PATHWAY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: KEGG_WNT_SIGNALING_PATHWAY: Random ES distribution   
Gene set null distribution of ES for KEGG_WNT_SIGNALING_PATHWAY