Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | FSHD2 |
| GeneSet | BIOCARTA_IL1R_PATHWAY |
| Enrichment Score (ES) | 0.4682692 |
| Normalized Enrichment Score (NES) | 1.5844591 |
| Nominal p-value | 0.016863406 |
| FDR q-value | 0.20016852 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | TGFB2 | ENSG00000092969.12 | 152 | 1.317 | 0.1356 | Yes | ||
| 2 | IL1RN | ENSG00000136689.18 | 579 | 0.987 | 0.2296 | Yes | ||
| 3 | IL1R1 | ENSG00000115594.12 | 1321 | 0.799 | 0.2961 | Yes | ||
| 4 | IFNA1 | ENSG00000197919.6 | 2927 | 0.612 | 0.3218 | Yes | ||
| 5 | MAP3K1 | ENSG00000095015.6 | 3142 | 0.596 | 0.3796 | Yes | ||
| 6 | IL1B | ENSG00000125538.12 | 3430 | 0.572 | 0.4332 | Yes | ||
| 7 | IL1A | ENSG00000115008.5 | 4274 | 0.526 | 0.4683 | Yes | ||
| 8 | MYD88 | ENSG00000172936.14 | 10743 | 0.301 | 0.3428 | No | ||
| 9 | TAB1 | ENSG00000100324.14 | 16096 | 0.143 | 0.2278 | No | ||
| 10 | IRAK1 | ENSG00000184216.14 | 16673 | 0.126 | 0.2271 | No | ||
| 11 | NFKB1 | ENSG00000109320.13 | 19218 | 0.059 | 0.1715 | No | ||
| 12 | IL1RAP | ENSG00000196083.10 | 19912 | 0.041 | 0.1590 | No | ||
| 13 | TGFB3 | ENSG00000119699.7 | 20364 | 0.029 | 0.1511 | No | ||
| 14 | IRAK3 | ENSG00000090376.11 | 21419 | 0.001 | 0.1255 | No | ||
| 15 | IKBKB | ENSG00000104365.15 | 21539 | -0.002 | 0.1229 | No | ||
| 16 | TNF | ENSG00000232810.4 | 21705 | -0.006 | 0.1195 | No | ||
| 17 | MAP3K14 | ENSG00000006062.17 | 22220 | -0.019 | 0.1090 | No | ||
| 18 | NFKBIA | ENSG00000100906.10 | 22848 | -0.035 | 0.0974 | No | ||
| 19 | RELA | ENSG00000173039.19 | 23632 | -0.056 | 0.0843 | No | ||
| 20 | MAPK8 | ENSG00000107643.16 | 23655 | -0.057 | 0.0897 | No | ||
| 21 | TRAF6 | ENSG00000175104.15 | 26280 | -0.128 | 0.0395 | No | ||
| 22 | MAPK14 | ENSG00000112062.10 | 26416 | -0.133 | 0.0503 | No | ||
| 23 | TGFB1 | ENSG00000105329.10 | 26855 | -0.145 | 0.0549 | No | ||
| 24 | MAP2K6 | ENSG00000108984.15 | 28890 | -0.208 | 0.0275 | No | ||
| 25 | MAP3K7 | ENSG00000135341.18 | 29362 | -0.223 | 0.0396 | No | ||
| 26 | IL6 | ENSG00000136244.12 | 29624 | -0.231 | 0.0578 | No | ||
| 27 | IRAK2 | ENSG00000134070.5 | 32907 | -0.332 | 0.0131 | No | ||
| 28 | CHUK | ENSG00000213341.11 | 36107 | -0.409 | -0.0213 | No | ||
| 29 | MAP2K3 | ENSG00000034152.19 | 38842 | -0.584 | -0.0260 | No | ||
| 30 | JUN | ENSG00000177606.7 | 40305 | -0.779 | 0.0208 | No |
