Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | FSHD2 |
| GeneSet | KEGG_HISTIDINE_METABOLISM |
| Enrichment Score (ES) | 0.48907533 |
| Normalized Enrichment Score (NES) | 1.6901951 |
| Nominal p-value | 0.008818342 |
| FDR q-value | 0.17213328 |
| FWER p-Value | 0.993 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HAL | ENSG00000084110.11 | 464 | 1.029 | 0.0863 | Yes | ||
| 2 | ALDH3A2 | ENSG00000072210.19 | 745 | 0.927 | 0.1674 | Yes | ||
| 3 | HDC | ENSG00000140287.11 | 854 | 0.897 | 0.2499 | Yes | ||
| 4 | HNMT | ENSG00000150540.14 | 1730 | 0.743 | 0.2990 | Yes | ||
| 5 | ALDH3A1 | ENSG00000108602.18 | 2386 | 0.664 | 0.3461 | Yes | ||
| 6 | HEMK1 | ENSG00000114735.9 | 3461 | 0.570 | 0.3740 | Yes | ||
| 7 | FTCD | ENSG00000160282.14 | 4777 | 0.506 | 0.3901 | Yes | ||
| 8 | ALDH3B2 | ENSG00000132746.14 | 5289 | 0.472 | 0.4224 | Yes | ||
| 9 | UROC1 | ENSG00000159650.9 | 5666 | 0.449 | 0.4559 | Yes | ||
| 10 | AMDHD1 | ENSG00000139344.8 | 5993 | 0.434 | 0.4891 | Yes | ||
| 11 | ACY3 | ENSG00000132744.8 | 9880 | 0.316 | 0.4246 | No | ||
| 12 | CNDP1 | ENSG00000150656.15 | 11672 | 0.283 | 0.4079 | No | ||
| 13 | TRMT11 | ENSG00000066651.20 | 13072 | 0.236 | 0.3963 | No | ||
| 14 | ALDH2 | ENSG00000111275.13 | 15545 | 0.158 | 0.3511 | No | ||
| 15 | BUD23 | ENSG00000071462.11 | 16762 | 0.123 | 0.3333 | No | ||
| 16 | LCMT1 | ENSG00000205629.12 | 16829 | 0.122 | 0.3432 | No | ||
| 17 | MAOA | ENSG00000189221.9 | 17441 | 0.106 | 0.3384 | No | ||
| 18 | ALDH7A1 | ENSG00000164904.18 | 20671 | 0.020 | 0.2618 | No | ||
| 19 | MAOB | ENSG00000069535.14 | 21045 | 0.010 | 0.2538 | No | ||
| 20 | METTL6 | ENSG00000206562.11 | 21200 | 0.007 | 0.2507 | No | ||
| 21 | METTL2B | ENSG00000165055.15 | 24283 | -0.073 | 0.1826 | No | ||
| 22 | ALDH9A1 | ENSG00000143149.12 | 26176 | -0.125 | 0.1485 | No | ||
| 23 | ASPA | ENSG00000108381.11 | 26231 | -0.127 | 0.1592 | No | ||
| 24 | LCMT2 | ENSG00000168806.8 | 26842 | -0.145 | 0.1581 | No | ||
| 25 | AOC1 | ENSG00000002726.20 | 26947 | -0.148 | 0.1696 | No | ||
| 26 | ALDH1A3 | ENSG00000184254.17 | 34635 | -0.353 | 0.0162 | No | ||
| 27 | DDC | ENSG00000132437.18 | 37176 | -0.462 | -0.0017 | No | ||
| 28 | ALDH1B1 | ENSG00000137124.8 | 37698 | -0.502 | 0.0332 | No | ||
| 29 | ALDH3B1 | ENSG00000006534.16 | 38133 | -0.537 | 0.0736 | No |
