Details for gene set NABA_CORE_MATRISOME[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	NABA_CORE_MATRISOME
Enrichment Score (ES)	0.3501
Normalized Enrichment Score (NES)	1.7441887
Nominal p-value	0.0
FDR q-value	0.12960571
FWER p-Value	0.959

Fig 1: Enrichment plot: NABA_CORE_MATRISOME   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	COL26A1	ENSG00000160963.14			26	1.811	0.0163	Yes
2	NELL2	ENSG00000184613.10			198	1.241	0.0238	Yes
3	COL14A1	ENSG00000187955.12			202	1.233	0.0353	Yes
4	COL11A2	ENSG00000204248.10			261	1.164	0.0447	Yes
5	FMOD	ENSG00000122176.12			266	1.161	0.0555	Yes
6	LAMA1	ENSG00000101680.15			292	1.136	0.0656	Yes
7	TECTA	ENSG00000109927.10			293	1.135	0.0762	Yes
8	BGLAP	ENSG00000242252.2			299	1.133	0.0867	Yes
9	COL9A3	ENSG00000092758.18			301	1.131	0.0972	Yes
10	VWCE	ENSG00000167992.13			337	1.099	0.1067	Yes
11	VWA5A	ENSG00000110002.16			433	1.042	0.1141	Yes
12	SPOCK1	ENSG00000152377.14			444	1.039	0.1236	Yes
13	MFAP4	ENSG00000166482.11			456	1.033	0.1330	Yes
14	GLDN	ENSG00000186417.14			573	0.990	0.1395	Yes
15	EFEMP1	ENSG00000115380.20			575	0.988	0.1487	Yes
16	RSPO1	ENSG00000169218.14			606	0.975	0.1571	Yes
17	SLIT1	ENSG00000187122.17			635	0.962	0.1654	Yes
18	FBLN1	ENSG00000077942.19			705	0.938	0.1725	Yes
19	CHAD	ENSG00000136457.10			741	0.927	0.1804	Yes
20	NTN4	ENSG00000074527.12			840	0.901	0.1864	Yes
21	MGP	ENSG00000111341.10			913	0.879	0.1929	Yes
22	TNN	ENSG00000120332.16			965	0.867	0.1998	Yes
23	NTN5	ENSG00000142233.11			1001	0.859	0.2070	Yes
24	HAPLN2	ENSG00000132702.13			1053	0.848	0.2136	Yes
25	TSPEAR	ENSG00000175894.18			1291	0.804	0.2154	Yes
26	RELN	ENSG00000189056.14			1303	0.802	0.2226	Yes
27	PCOLCE2	ENSG00000163710.9			1312	0.800	0.2299	Yes
28	TINAG	ENSG00000137251.16			1358	0.793	0.2363	Yes
29	PRG2	ENSG00000186652.10			1606	0.758	0.2373	Yes
30	VWA5B2	ENSG00000145198.14			1649	0.754	0.2434	Yes
31	EDIL3	ENSG00000164176.13			1748	0.740	0.2479	Yes
32	NTNG1	ENSG00000162631.18			1784	0.736	0.2539	Yes
33	LTBP4	ENSG00000090006.17			1825	0.729	0.2598	Yes
34	EMID1	ENSG00000186998.16			1845	0.725	0.2661	Yes
35	SNED1	ENSG00000162804.14			1875	0.721	0.2722	Yes
36	LAMB4	ENSG00000091128.13			2043	0.699	0.2746	Yes
37	LTBP1	ENSG00000049323.16			2175	0.686	0.2778	Yes
38	IGFBP3	ENSG00000146674.15			2420	0.661	0.2781	Yes
39	SMOC2	ENSG00000112562.18			2598	0.644	0.2798	Yes
40	NTNG2	ENSG00000196358.11			2685	0.635	0.2836	Yes
41	CRISPLD1	ENSG00000121005.9			2756	0.628	0.2878	Yes
42	COL6A6	ENSG00000206384.10			2896	0.614	0.2901	Yes
43	COL25A1	ENSG00000188517.16			3211	0.590	0.2880	Yes
44	LUM	ENSG00000139329.5			3247	0.588	0.2926	Yes
45	PRG4	ENSG00000116690.12			3250	0.588	0.2981	Yes
46	RSPO3	ENSG00000146374.14			3267	0.586	0.3032	Yes
47	SBSPON	ENSG00000164764.11			3341	0.581	0.3069	Yes
48	LAMB1	ENSG00000091136.14			3394	0.576	0.3110	Yes
49	SPON1	ENSG00000262655.4			3535	0.565	0.3129	Yes
50	IGFBP4	ENSG00000141753.7			3723	0.556	0.3135	Yes
51	MMRN2	ENSG00000173269.14			3779	0.551	0.3173	Yes
52	CRELD1	ENSG00000163703.17			4296	0.524	0.3096	Yes
53	LGI3	ENSG00000168481.9			4431	0.519	0.3112	Yes
54	SSPO	ENSG00000197558.12			4521	0.518	0.3139	Yes
55	HAPLN3	ENSG00000140511.11			4726	0.509	0.3136	Yes
56	LAMC3	ENSG00000050555.18			4992	0.492	0.3118	Yes
57	COL22A1	ENSG00000169436.17			5053	0.487	0.3149	Yes
58	COL4A4	ENSG00000081052.12			5076	0.485	0.3189	Yes
59	COL21A1	ENSG00000124749.17			5120	0.482	0.3223	Yes
60	LAMA3	ENSG00000053747.16			5156	0.480	0.3260	Yes
61	CCN5	ENSG00000064205.10			5220	0.476	0.3289	Yes
62	VWF	ENSG00000110799.13			5222	0.476	0.3333	Yes
63	ANOS1	ENSG00000011201.12			5269	0.473	0.3367	Yes
64	NID2	ENSG00000087303.18			5592	0.454	0.3330	Yes
65	LAMA5	ENSG00000130702.15			5685	0.448	0.3350	Yes
66	EYS	ENSG00000188107.15			5877	0.440	0.3344	Yes
67	PCOLCE	ENSG00000106333.13			5878	0.440	0.3385	Yes
68	COLQ	ENSG00000206561.13			6095	0.428	0.3373	Yes
69	SPARCL1	ENSG00000152583.12			6166	0.425	0.3396	Yes
70	COCH	ENSG00000100473.18			6222	0.421	0.3422	Yes
71	COL2A1	ENSG00000139219.19			6306	0.417	0.3440	Yes
72	COL16A1	ENSG00000084636.18			6521	0.407	0.3426	Yes
73	LTBP3	ENSG00000168056.16			6522	0.407	0.3464	Yes
74	LGI4	ENSG00000153902.14			6529	0.407	0.3501	Yes
75	NTN3	ENSG00000162068.2			6808	0.396	0.3470	No
76	CCN3	ENSG00000136999.5			6958	0.391	0.3470	No
77	RSPO2	ENSG00000147655.12			7153	0.382	0.3459	No
78	FGG	ENSG00000171557.17			7287	0.376	0.3461	No
79	COL23A1	ENSG00000050767.17			7594	0.367	0.3421	No
80	VWA7	ENSG00000204396.11			7599	0.367	0.3454	No
81	ADIPOQ	ENSG00000181092.10			7776	0.363	0.3445	No
82	HAPLN4	ENSG00000187664.9			8255	0.352	0.3361	No
83	COL9A1	ENSG00000112280.16			8277	0.352	0.3389	No
84	ZP2	ENSG00000103310.10			8318	0.352	0.3413	No
85	BGN	ENSG00000182492.16			8477	0.352	0.3407	No
86	MEPE	ENSG00000152595.16			8577	0.348	0.3415	No
87	VWA2	ENSG00000165816.13			8831	0.342	0.3386	No
88	COL27A1	ENSG00000196739.15			8861	0.341	0.3410	No
89	OPTC	ENSG00000188770.10			8936	0.338	0.3424	No
90	COL20A1	ENSG00000101203.16			9244	0.326	0.3379	No
91	OGN	ENSG00000106809.11			9884	0.316	0.3253	No
92	COL24A1	ENSG00000171502.15			10695	0.303	0.3083	No
93	FNDC1	ENSG00000164694.17			10822	0.298	0.3080	No
94	PXDNL	ENSG00000147485.13			11090	0.288	0.3042	No
95	DSPP	ENSG00000152591.15			11156	0.285	0.3053	No
96	TNR	ENSG00000116147.17			11282	0.285	0.3049	No
97	CTHRC1	ENSG00000164932.13			11661	0.284	0.2983	No
98	CHADL	ENSG00000100399.16			11790	0.279	0.2978	No
99	VWA3A	ENSG00000175267.15			12007	0.271	0.2950	No
100	COL6A3	ENSG00000163359.15			12073	0.268	0.2960	No
101	COL28A1	ENSG00000215018.10			12515	0.254	0.2876	No
102	NID1	ENSG00000116962.15			12648	0.250	0.2867	No
103	COL13A1	ENSG00000197467.14			12717	0.247	0.2873	No
104	BCAN	ENSG00000132692.19			12750	0.246	0.2888	No
105	USH2A	ENSG00000042781.13			12814	0.244	0.2896	No
106	CCN6	ENSG00000112761.20			13264	0.230	0.2808	No
107	VTN	ENSG00000109072.14			13279	0.229	0.2826	No
108	IGFBPL1	ENSG00000137142.5			13388	0.226	0.2820	No
109	IGFBP2	ENSG00000115457.10			13426	0.224	0.2832	No
110	MATN4	ENSG00000124159.15			13437	0.223	0.2851	No
111	MATN1	ENSG00000162510.6			13868	0.210	0.2765	No
112	TNFAIP6	ENSG00000123610.5			14070	0.204	0.2735	No
113	PRELP	ENSG00000188783.6			14400	0.194	0.2673	No
114	LAMA2	ENSG00000196569.12			14748	0.182	0.2605	No
115	COL6A2	ENSG00000142173.15			14929	0.176	0.2578	No
116	COL4A3	ENSG00000169031.19			15183	0.168	0.2532	No
117	IGFALS	ENSG00000099769.5			15231	0.167	0.2536	No
118	VWA3B	ENSG00000168658.19			15379	0.162	0.2515	No
119	SPON2	ENSG00000159674.12			15536	0.158	0.2492	No
120	HMCN2	ENSG00000148357.16			15639	0.155	0.2481	No
121	MFGE8	ENSG00000140545.15			15705	0.153	0.2480	No
122	EMILIN3	ENSG00000183798.5			15977	0.146	0.2427	No
123	IGSF10	ENSG00000152580.8			16016	0.145	0.2431	No
124	EMILIN1	ENSG00000138080.14			16451	0.132	0.2338	No
125	LGI1	ENSG00000108231.13			16455	0.132	0.2349	No
126	COL8A2	ENSG00000171812.13			16605	0.128	0.2325	No
127	COL7A1	ENSG00000114270.17			16820	0.122	0.2284	No
128	SMOC1	ENSG00000198732.10			16826	0.122	0.2294	No
129	NTN1	ENSG00000065320.9			17067	0.116	0.2246	No
130	COL4A6	ENSG00000197565.15			17112	0.114	0.2246	No
131	SVEP1	ENSG00000165124.18			17205	0.112	0.2234	No
132	LAMB3	ENSG00000196878.15			17382	0.108	0.2201	No
133	SPOCK2	ENSG00000107742.13			17942	0.092	0.2073	No
134	AGRN	ENSG00000188157.15			18021	0.090	0.2063	No
135	FBN1	ENSG00000166147.13			18163	0.087	0.2036	No
136	COL6A1	ENSG00000142156.14			18165	0.087	0.2044	No
137	OMD	ENSG00000127083.7			18338	0.083	0.2010	No
138	SLIT3	ENSG00000184347.14			18947	0.067	0.1867	No
139	KCP	ENSG00000135253.13			18949	0.066	0.1873	No
140	ZP1	ENSG00000149506.11			19012	0.065	0.1864	No
141	CRELD2	ENSG00000184164.14			19149	0.061	0.1837	No
142	CILP2	ENSG00000160161.9			19234	0.059	0.1822	No
143	COL5A3	ENSG00000080573.7			19257	0.058	0.1822	No
144	THBS2	ENSG00000186340.15			19463	0.052	0.1777	No
145	SPOCK3	ENSG00000196104.11			19732	0.045	0.1715	No
146	MFAP2	ENSG00000117122.14			19781	0.044	0.1708	No
147	DCN	ENSG00000011465.17			20288	0.032	0.1587	No
148	VIT	ENSG00000205221.12			20556	0.023	0.1524	No
149	NELL1	ENSG00000165973.19			20760	0.019	0.1476	No
150	FGA	ENSG00000171560.16			20943	0.014	0.1433	No
151	VCAN	ENSG00000038427.16			20990	0.012	0.1423	No
152	AMELX	ENSG00000125363.14			21206	0.007	0.1371	No
153	FBLN2	ENSG00000163520.14			21217	0.006	0.1369	No
154	CRISPLD2	ENSG00000103196.12			21721	-0.007	0.1246	No
155	COL8A1	ENSG00000144810.16			21914	-0.012	0.1201	No
156	THBS1	ENSG00000137801.11			22033	-0.015	0.1173	No
157	INTS14	ENSG00000138614.15			22139	-0.016	0.1149	No
158	CCN2	ENSG00000118523.6			22253	-0.019	0.1123	No
159	TSKU	ENSG00000182704.8			22329	-0.022	0.1107	No
160	FNDC8	ENSG00000073598.6			22463	-0.026	0.1077	No
161	COL5A1	ENSG00000130635.15			22567	-0.028	0.1054	No
162	PXDN	ENSG00000130508.11			22625	-0.029	0.1043	No
163	PAPLN	ENSG00000100767.16			22695	-0.031	0.1029	No
164	COL18A1	ENSG00000182871.16			22895	-0.036	0.0984	No
165	COL1A2	ENSG00000164692.17			23053	-0.041	0.0949	No
166	COL1A1	ENSG00000108821.13			23206	-0.045	0.0916	No
167	EMILIN2	ENSG00000132205.11			23319	-0.047	0.0893	No
168	HSPG2	ENSG00000142798.20			24057	-0.066	0.0719	No
169	VWA1	ENSG00000179403.12			24198	-0.070	0.0691	No
170	IMPG2	ENSG00000081148.12			24354	-0.075	0.0660	No
171	PODN	ENSG00000174348.13			24474	-0.076	0.0639	No
172	OIT3	ENSG00000138315.13			24592	-0.080	0.0617	No
173	COL3A1	ENSG00000168542.14			24737	-0.084	0.0590	No
174	COL4A5	ENSG00000188153.13			24793	-0.085	0.0585	No
175	LAMA4	ENSG00000112769.20			24827	-0.086	0.0585	No
176	EFEMP2	ENSG00000172638.13			24938	-0.090	0.0566	No
177	IMPG1	ENSG00000112706.12			25707	-0.111	0.0389	No
178	ACAN	ENSG00000157766.17			25721	-0.112	0.0396	No
179	DMP1	ENSG00000152592.14			26068	-0.123	0.0323	No
180	FBN2	ENSG00000138829.12			26300	-0.129	0.0279	No
181	FNDC7	ENSG00000143107.10			26336	-0.130	0.0282	No
182	COL4A2	ENSG00000134871.19			26354	-0.131	0.0290	No
183	PODNL1	ENSG00000132000.13			26840	-0.145	0.0185	No
184	IGFBP5	ENSG00000115461.5			27066	-0.151	0.0144	No
185	TNXB	ENSG00000168477.19			27304	-0.158	0.0101	No
186	THBS3	ENSG00000169231.13			27375	-0.160	0.0099	No
187	COL15A1	ENSG00000204291.11			27409	-0.161	0.0106	No
188	NCAN	ENSG00000130287.14			27413	-0.161	0.0121	No
189	MATN2	ENSG00000132561.14			27429	-0.162	0.0132	No
190	SPARC	ENSG00000113140.11			28014	-0.181	0.0006	No
191	COL11A1	ENSG00000060718.22			28377	-0.192	-0.0064	No
192	MFAP3	ENSG00000037749.12			28424	-0.194	-0.0057	No
193	ECM2	ENSG00000106823.12			28489	-0.196	-0.0055	No
194	ZP3	ENSG00000188372.15			28519	-0.197	-0.0043	No
195	IGFBP1	ENSG00000146678.10			28557	-0.198	-0.0034	No
196	LTBP2	ENSG00000119681.12			28615	-0.200	-0.0029	No
197	LAMC1	ENSG00000135862.6			28753	-0.203	-0.0044	No
198	COL12A1	ENSG00000111799.21			29059	-0.214	-0.0098	No
199	MFAP1	ENSG00000140259.7			29124	-0.216	-0.0094	No
200	POMZP3	ENSG00000146707.14			29178	-0.217	-0.0086	No
201	CCN1	ENSG00000142871.17			30290	-0.253	-0.0334	No
202	MXRA5	ENSG00000101825.8			30601	-0.263	-0.0385	No
203	INTS6L	ENSG00000165359.15			30623	-0.263	-0.0366	No
204	RSPO4	ENSG00000101282.9			30644	-0.264	-0.0346	No
205	EGFLAM	ENSG00000164318.18			30681	-0.265	-0.0330	No
206	COMP	ENSG00000105664.11			31006	-0.277	-0.0383	No
207	FBN3	ENSG00000142449.13			31009	-0.277	-0.0358	No
208	SRPX	ENSG00000101955.15			31035	-0.278	-0.0338	No
209	FBLN5	ENSG00000140092.14			31116	-0.281	-0.0331	No
210	LAMC2	ENSG00000058085.15			31167	-0.284	-0.0317	No
211	THSD4	ENSG00000187720.14			31761	-0.288	-0.0435	No
212	ESM1	ENSG00000164283.13			31854	-0.292	-0.0430	No
213	LGI2	ENSG00000153012.12			32016	-0.297	-0.0441	No
214	MFAP5	ENSG00000197614.11			32055	-0.298	-0.0423	No
215	COL19A1	ENSG00000082293.13			32153	-0.302	-0.0418	No
216	COL5A2	ENSG00000204262.14			32186	-0.304	-0.0397	No
217	COL6A5	ENSG00000172752.14			32299	-0.309	-0.0396	No
218	DMBT1	ENSG00000187908.19			32453	-0.315	-0.0404	No
219	FGL2	ENSG00000127951.7			32655	-0.323	-0.0423	No
220	LAMB2	ENSG00000172037.14			32705	-0.324	-0.0404	No
221	VWA5B1	ENSG00000158816.15			32729	-0.325	-0.0379	No
222	FGB	ENSG00000171564.11			33043	-0.336	-0.0424	No
223	ABI3BP	ENSG00000154175.17			33553	-0.338	-0.0517	No
224	THBS4	ENSG00000113296.14			34200	-0.350	-0.0642	No
225	ELN	ENSG00000049540.17			35316	-0.380	-0.0879	No
226	ASPN	ENSG00000106819.13			36236	-0.413	-0.1066	No
227	TINAGL1	ENSG00000142910.16			36281	-0.415	-0.1037	No
228	CCN4	ENSG00000104415.14			36365	-0.419	-0.1018	No
229	COL4A1	ENSG00000187498.16			36388	-0.420	-0.0984	No
230	IGFBP7	ENSG00000163453.11			36410	-0.421	-0.0950	No
231	TNC	ENSG00000041982.16			36501	-0.427	-0.0932	No
232	COL9A2	ENSG00000049089.15			36608	-0.432	-0.0918	No
233	AEBP1	ENSG00000106624.11			36626	-0.432	-0.0881	No
234	FBLN7	ENSG00000144152.13			36684	-0.435	-0.0854	No
235	POSTN	ENSG00000133110.15			36812	-0.441	-0.0844	No
236	CILP	ENSG00000138615.6			36960	-0.449	-0.0838	No
237	SRPX2	ENSG00000102359.7			37299	-0.471	-0.0877	No
238	CRIM1	ENSG00000150938.10			37543	-0.488	-0.0890	No
239	SRGN	ENSG00000122862.5			37616	-0.495	-0.0861	No
240	TGFBI	ENSG00000120708.17			37818	-0.514	-0.0862	No
241	ZPLD1	ENSG00000170044.8			37968	-0.525	-0.0850	No
242	SLIT2	ENSG00000145147.20			38005	-0.528	-0.0809	No
243	KERA	ENSG00000139330.5			38199	-0.543	-0.0805	No
244	NYX	ENSG00000188937.5			38377	-0.556	-0.0797	No
245	OTOG	ENSG00000188162.11			38476	-0.558	-0.0768	No
246	TECTB	ENSG00000119913.6			38653	-0.566	-0.0758	No
247	SPP1	ENSG00000118785.14			38686	-0.569	-0.0713	No
248	FRAS1	ENSG00000138759.19			38912	-0.591	-0.0712	No
249	EPYC	ENSG00000083782.8			39077	-0.611	-0.0695	No
250	IGFBP6	ENSG00000167779.9			39424	-0.628	-0.0721	No
251	IBSP	ENSG00000029559.7			39472	-0.633	-0.0673	No
252	NPNT	ENSG00000168743.12			39626	-0.650	-0.0650	No
253	HAPLN1	ENSG00000145681.11			39630	-0.650	-0.0589	No
254	COL17A1	ENSG00000065618.21			39690	-0.661	-0.0542	No
255	NDNF	ENSG00000173376.14			39706	-0.662	-0.0484	No
256	ECM1	ENSG00000143369.15			39921	-0.699	-0.0470	No
257	GAS6	ENSG00000183087.15			39997	-0.713	-0.0422	No
258	DPT	ENSG00000143196.5			40183	-0.749	-0.0397	No
259	COL10A1	ENSG00000123500.10			40191	-0.750	-0.0329	No
260	HMCN1	ENSG00000143341.12			40444	-0.822	-0.0313	No
261	FN1	ENSG00000115414.19			40842	-0.991	-0.0317	No
262	MATN3	ENSG00000132031.13			41030	-1.191	-0.0252	No
263	BMPER	ENSG00000164619.10			41089	-1.386	-0.0136	No
264	VWDE	ENSG00000146530.14			41124	-1.636	0.0009	No

Fig 2: NABA_CORE_MATRISOME   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: NABA_CORE_MATRISOME: Random ES distribution   
Gene set null distribution of ES for NABA_CORE_MATRISOME