Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | PID_AURORA_A_PATHWAY |
| Enrichment Score (ES) | -0.63482696 |
| Normalized Enrichment Score (NES) | -2.3859928 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.520282E-5 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CPEB1 | ENSG00000214575.9 | 2509 | 0.653 | 0.0097 | No | ||
| 2 | CDC25B | ENSG00000101224.17 | 15629 | 0.156 | -0.2924 | No | ||
| 3 | AURKAIP1 | ENSG00000175756.13 | 21621 | -0.004 | -0.4376 | No | ||
| 4 | AKT1 | ENSG00000142208.16 | 21695 | -0.006 | -0.4387 | No | ||
| 5 | ARHGEF7 | ENSG00000102606.18 | 21717 | -0.007 | -0.4385 | No | ||
| 6 | NFKBIA | ENSG00000100906.10 | 22848 | -0.035 | -0.4623 | No | ||
| 7 | NDEL1 | ENSG00000166579.15 | 22882 | -0.036 | -0.4592 | No | ||
| 8 | GADD45A | ENSG00000116717.13 | 23989 | -0.064 | -0.4792 | No | ||
| 9 | GIT1 | ENSG00000108262.15 | 24150 | -0.068 | -0.4757 | No | ||
| 10 | PRKACA | ENSG00000072062.14 | 24521 | -0.077 | -0.4763 | No | ||
| 11 | MDM2 | ENSG00000135679.25 | 24559 | -0.079 | -0.4687 | No | ||
| 12 | FZR1 | ENSG00000105325.14 | 24842 | -0.087 | -0.4661 | No | ||
| 13 | PPP2R5D | ENSG00000112640.15 | 24932 | -0.090 | -0.4586 | No | ||
| 14 | TP53 | ENSG00000141510.17 | 27245 | -0.156 | -0.4979 | No | ||
| 15 | OAZ1 | ENSG00000104904.12 | 27453 | -0.163 | -0.4853 | No | ||
| 16 | AJUBA | ENSG00000129474.16 | 29753 | -0.236 | -0.5157 | No | ||
| 17 | RASA1 | ENSG00000145715.15 | 34655 | -0.354 | -0.5965 | Yes | ||
| 18 | TACC3 | ENSG00000013810.19 | 35296 | -0.378 | -0.5711 | Yes | ||
| 19 | TACC1 | ENSG00000147526.20 | 35303 | -0.379 | -0.5303 | Yes | ||
| 20 | BIRC5 | ENSG00000089685.15 | 36279 | -0.415 | -0.5091 | Yes | ||
| 21 | RAN | ENSG00000132341.12 | 36507 | -0.427 | -0.4684 | Yes | ||
| 22 | PAK1 | ENSG00000149269.9 | 36549 | -0.430 | -0.4229 | Yes | ||
| 23 | AURKB | ENSG00000178999.13 | 37485 | -0.484 | -0.3933 | Yes | ||
| 24 | GSK3B | ENSG00000082701.15 | 37577 | -0.491 | -0.3423 | Yes | ||
| 25 | DLGAP5 | ENSG00000126787.13 | 37762 | -0.508 | -0.2918 | Yes | ||
| 26 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.2375 | Yes | ||
| 27 | CENPA | ENSG00000115163.15 | 37993 | -0.527 | -0.1848 | Yes | ||
| 28 | AURKA | ENSG00000087586.17 | 38638 | -0.565 | -0.1393 | Yes | ||
| 29 | TPX2 | ENSG00000088325.16 | 38681 | -0.569 | -0.0787 | Yes | ||
| 30 | TDRD7 | ENSG00000196116.8 | 38973 | -0.598 | -0.0211 | Yes | ||
| 31 | BRCA1 | ENSG00000012048.22 | 39857 | -0.687 | 0.0317 | Yes |
