Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | PID_ILK_PATHWAY |
| Enrichment Score (ES) | -0.55658996 |
| Normalized Enrichment Score (NES) | -2.2831962 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.8028426E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PPP1R14C | ENSG00000198729.5 | 661 | 0.955 | 0.0464 | No | ||
| 2 | SNAI1 | ENSG00000124216.4 | 12117 | 0.267 | -0.2147 | No | ||
| 3 | ILK | ENSG00000166333.13 | 13665 | 0.217 | -0.2381 | No | ||
| 4 | ILKAP | ENSG00000132323.9 | 15087 | 0.171 | -0.2615 | No | ||
| 5 | NCK2 | ENSG00000071051.14 | 17333 | 0.109 | -0.3089 | No | ||
| 6 | RICTOR | ENSG00000164327.13 | 19806 | 0.043 | -0.3662 | No | ||
| 7 | AKT1 | ENSG00000142208.16 | 21695 | -0.006 | -0.4117 | No | ||
| 8 | ARHGEF7 | ENSG00000102606.18 | 21717 | -0.007 | -0.4118 | No | ||
| 9 | PPP1R14A | ENSG00000167641.11 | 22008 | -0.015 | -0.4179 | No | ||
| 10 | CDC37 | ENSG00000105401.9 | 23007 | -0.040 | -0.4396 | No | ||
| 11 | PXN | ENSG00000089159.16 | 24055 | -0.066 | -0.4608 | No | ||
| 12 | CTNNB1 | ENSG00000168036.18 | 24288 | -0.073 | -0.4616 | No | ||
| 13 | TNS1 | ENSG00000079308.19 | 24766 | -0.084 | -0.4677 | No | ||
| 14 | ZYX | ENSG00000159840.16 | 25419 | -0.103 | -0.4768 | No | ||
| 15 | NACA | ENSG00000196531.11 | 26863 | -0.145 | -0.5024 | No | ||
| 16 | RHOG | ENSG00000177105.10 | 26871 | -0.145 | -0.4931 | No | ||
| 17 | CREB1 | ENSG00000118260.15 | 27269 | -0.157 | -0.4924 | No | ||
| 18 | ACTN1 | ENSG00000072110.13 | 28265 | -0.188 | -0.5043 | No | ||
| 19 | RUVBL2 | ENSG00000183207.14 | 28623 | -0.200 | -0.4999 | No | ||
| 20 | PARP1 | ENSG00000143799.13 | 28744 | -0.203 | -0.4895 | No | ||
| 21 | ELMO2 | ENSG00000062598.18 | 29480 | -0.226 | -0.4926 | No | ||
| 22 | PARVG | ENSG00000138964.17 | 29768 | -0.237 | -0.4841 | No | ||
| 23 | DIAPH1 | ENSG00000131504.17 | 29982 | -0.243 | -0.4733 | No | ||
| 24 | ARHGEF6 | ENSG00000129675.16 | 30786 | -0.269 | -0.4752 | No | ||
| 25 | LIMS2 | ENSG00000072163.19 | 34132 | -0.347 | -0.5339 | Yes | ||
| 26 | LIMS1 | ENSG00000169756.16 | 34742 | -0.358 | -0.5253 | Yes | ||
| 27 | TACC3 | ENSG00000013810.19 | 35296 | -0.378 | -0.5140 | Yes | ||
| 28 | PPP1R14B | ENSG00000173457.11 | 36245 | -0.413 | -0.5100 | Yes | ||
| 29 | GIT2 | ENSG00000139436.21 | 37018 | -0.453 | -0.4991 | Yes | ||
| 30 | ZEB1 | ENSG00000148516.21 | 37086 | -0.457 | -0.4708 | Yes | ||
| 31 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.4438 | Yes | ||
| 32 | RAC1 | ENSG00000136238.18 | 37298 | -0.471 | -0.4146 | Yes | ||
| 33 | PARVB | ENSG00000188677.14 | 37513 | -0.486 | -0.3880 | Yes | ||
| 34 | GSK3B | ENSG00000082701.15 | 37577 | -0.491 | -0.3574 | Yes | ||
| 35 | CKAP5 | ENSG00000175216.15 | 37814 | -0.514 | -0.3295 | Yes | ||
| 36 | HSP90AA1 | ENSG00000080824.18 | 37823 | -0.514 | -0.2960 | Yes | ||
| 37 | PARVA | ENSG00000197702.14 | 37874 | -0.518 | -0.2633 | Yes | ||
| 38 | CDC42 | ENSG00000070831.17 | 38194 | -0.542 | -0.2355 | Yes | ||
| 39 | CCND1 | ENSG00000110092.3 | 38307 | -0.552 | -0.2021 | Yes | ||
| 40 | IQGAP1 | ENSG00000140575.13 | 38621 | -0.564 | -0.1728 | Yes | ||
| 41 | AURKA | ENSG00000087586.17 | 38638 | -0.565 | -0.1362 | Yes | ||
| 42 | RUVBL1 | ENSG00000175792.12 | 39033 | -0.604 | -0.1062 | Yes | ||
| 43 | PPP1R12A | ENSG00000058272.19 | 40248 | -0.765 | -0.0857 | Yes | ||
| 44 | JUN | ENSG00000177606.7 | 40305 | -0.779 | -0.0360 | Yes | ||
| 45 | MYL9 | ENSG00000101335.10 | 40576 | -0.868 | 0.0142 | Yes |
