Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX |
| Enrichment Score (ES) | -0.6058788 |
| Normalized Enrichment Score (NES) | -2.2708461 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.1385227E-4 |
| FWER p-Value | 0.007 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | POLE4 | ENSG00000115350.12 | 15368 | 0.163 | -0.3592 | No | ||
| 2 | RPA2 | ENSG00000117748.10 | 16945 | 0.118 | -0.3871 | No | ||
| 3 | MCM7 | ENSG00000166508.17 | 17495 | 0.104 | -0.3913 | No | ||
| 4 | POLE | ENSG00000177084.17 | 19403 | 0.054 | -0.4329 | No | ||
| 5 | ORC2 | ENSG00000115942.9 | 19607 | 0.048 | -0.4335 | No | ||
| 6 | ORC5 | ENSG00000164815.11 | 23413 | -0.050 | -0.5216 | No | ||
| 7 | POLE3 | ENSG00000148229.13 | 23456 | -0.051 | -0.5181 | No | ||
| 8 | POLA2 | ENSG00000014138.9 | 24862 | -0.087 | -0.5445 | No | ||
| 9 | DBF4 | ENSG00000006634.8 | 25980 | -0.120 | -0.5611 | No | ||
| 10 | POLA1 | ENSG00000101868.11 | 26537 | -0.136 | -0.5626 | No | ||
| 11 | GMNN | ENSG00000112312.10 | 27728 | -0.171 | -0.5763 | No | ||
| 12 | RPA4 | ENSG00000204086.4 | 28029 | -0.182 | -0.5676 | No | ||
| 13 | ORC4 | ENSG00000115947.13 | 28129 | -0.185 | -0.5536 | No | ||
| 14 | MCM3 | ENSG00000112118.20 | 29007 | -0.212 | -0.5562 | No | ||
| 15 | MCM8 | ENSG00000125885.13 | 31052 | -0.279 | -0.5812 | Yes | ||
| 16 | RPA1 | ENSG00000132383.12 | 31119 | -0.282 | -0.5579 | Yes | ||
| 17 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.5581 | Yes | ||
| 18 | MCM2 | ENSG00000073111.14 | 32546 | -0.318 | -0.5372 | Yes | ||
| 19 | MCM6 | ENSG00000076003.5 | 34728 | -0.357 | -0.5586 | Yes | ||
| 20 | CDT1 | ENSG00000167513.9 | 35789 | -0.401 | -0.5489 | Yes | ||
| 21 | MCM5 | ENSG00000100297.16 | 35805 | -0.402 | -0.5136 | Yes | ||
| 22 | ORC3 | ENSG00000135336.14 | 36389 | -0.421 | -0.4906 | Yes | ||
| 23 | RPA3 | ENSG00000106399.11 | 36661 | -0.434 | -0.4587 | Yes | ||
| 24 | ORC1 | ENSG00000085840.13 | 37179 | -0.462 | -0.4304 | Yes | ||
| 25 | POLE2 | ENSG00000100479.13 | 37582 | -0.492 | -0.3966 | Yes | ||
| 26 | CDC7 | ENSG00000097046.13 | 38052 | -0.531 | -0.3610 | Yes | ||
| 27 | PRIM1 | ENSG00000198056.15 | 38325 | -0.554 | -0.3185 | Yes | ||
| 28 | CDC45 | ENSG00000093009.10 | 38822 | -0.583 | -0.2790 | Yes | ||
| 29 | ORC6 | ENSG00000091651.9 | 38888 | -0.589 | -0.2284 | Yes | ||
| 30 | PRIM2 | ENSG00000146143.19 | 39937 | -0.702 | -0.1918 | Yes | ||
| 31 | CDC6 | ENSG00000094804.12 | 40060 | -0.723 | -0.1307 | Yes | ||
| 32 | MCM4 | ENSG00000104738.18 | 40591 | -0.872 | -0.0665 | Yes | ||
| 33 | MCM10 | ENSG00000065328.16 | 40670 | -0.907 | 0.0119 | Yes |
