Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | FSHD2 |
| GeneSet | REACTOME_CHOLESTEROL_BIOSYNTHESIS |
| Enrichment Score (ES) | 0.4910822 |
| Normalized Enrichment Score (NES) | 1.6288521 |
| Nominal p-value | 0.011608624 |
| FDR q-value | 0.17732479 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | ENSG00000116133.13 | 2975 | 0.608 | 0.0151 | Yes | ||
| 2 | MVD | ENSG00000167508.12 | 4547 | 0.516 | 0.0511 | Yes | ||
| 3 | DHCR7 | ENSG00000172893.15 | 4598 | 0.514 | 0.1238 | Yes | ||
| 4 | HMGCR | ENSG00000113161.16 | 5676 | 0.449 | 0.1621 | Yes | ||
| 5 | PLPP6 | ENSG00000205808.6 | 5686 | 0.448 | 0.2264 | Yes | ||
| 6 | EBP | ENSG00000147155.11 | 6973 | 0.391 | 0.2513 | Yes | ||
| 7 | SC5D | ENSG00000109929.10 | 7132 | 0.384 | 0.3026 | Yes | ||
| 8 | LBR | ENSG00000143815.15 | 7515 | 0.370 | 0.3465 | Yes | ||
| 9 | TM7SF2 | ENSG00000149809.15 | 7658 | 0.364 | 0.3955 | Yes | ||
| 10 | CYP51A1 | ENSG00000001630.17 | 10022 | 0.310 | 0.3827 | Yes | ||
| 11 | MVK | ENSG00000110921.14 | 10148 | 0.305 | 0.4236 | Yes | ||
| 12 | HMGCS1 | ENSG00000112972.15 | 11768 | 0.279 | 0.4244 | Yes | ||
| 13 | FDFT1 | ENSG00000079459.13 | 12228 | 0.263 | 0.4511 | Yes | ||
| 14 | FDPS | ENSG00000160752.14 | 13271 | 0.229 | 0.4587 | Yes | ||
| 15 | MSMO1 | ENSG00000052802.13 | 13294 | 0.229 | 0.4911 | Yes | ||
| 16 | SQLE | ENSG00000104549.12 | 16232 | 0.139 | 0.4396 | No | ||
| 17 | ACAT2 | ENSG00000120437.9 | 18961 | 0.066 | 0.3828 | No | ||
| 18 | IDI1 | ENSG00000067064.11 | 20552 | 0.023 | 0.3475 | No | ||
| 19 | LSS | ENSG00000160285.15 | 21576 | -0.003 | 0.3232 | No | ||
| 20 | HSD17B7 | ENSG00000132196.14 | 22040 | -0.015 | 0.3141 | No | ||
| 21 | ARV1 | ENSG00000173409.14 | 23808 | -0.061 | 0.2799 | No | ||
| 22 | NSDHL | ENSG00000147383.11 | 24881 | -0.088 | 0.2664 | No | ||
| 23 | IDI2 | ENSG00000148377.6 | 25933 | -0.118 | 0.2579 | No | ||
| 24 | PMVK | ENSG00000163344.6 | 32790 | -0.327 | 0.1382 | No | ||
| 25 | GGPS1 | ENSG00000152904.11 | 37024 | -0.454 | 0.1006 | No |
