Details for gene set REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
Enrichment Score (ES)	0.57747173
Normalized Enrichment Score (NES)	1.6693226
Nominal p-value	0.016638935
FDR q-value	0.15561283
FWER p-Value	0.997

Fig 1: Enrichment plot: REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1S	ENSG00000182326.15			1233	0.811	0.1152	Yes
2	COLEC11	ENSG00000118004.17			2760	0.627	0.1903	Yes
3	C1R	ENSG00000159403.18			2987	0.607	0.2934	Yes
4	MASP2	ENSG00000009724.17			4725	0.509	0.3422	Yes
5	FCN1	ENSG00000085265.11			7665	0.364	0.3359	Yes
6	IGLV1-51	ENSG00000211644.3			7791	0.363	0.3978	Yes
7	IGLV3-1	ENSG00000211673.2			7856	0.362	0.4610	Yes
8	COLEC10	ENSG00000184374.3			8219	0.353	0.5153	Yes
9	MBL2	ENSG00000165471.6			9409	0.319	0.5435	Yes
10	CRP	ENSG00000132693.12			10259	0.305	0.5775	Yes
11	MASP1	ENSG00000127241.16			13988	0.206	0.5237	No
12	FCN3	ENSG00000142748.12			21773	-0.008	0.3361	No
13	IGLC2	ENSG00000211677.2			22079	-0.016	0.3315	No
14	C1QB	ENSG00000173369.16			33116	-0.336	0.1235	No
15	C1QA	ENSG00000173372.17			35837	-0.402	0.1294	No

Fig 2: REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS: Random ES distribution   
Gene set null distribution of ES for REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS