Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION |
| Enrichment Score (ES) | -0.65046734 |
| Normalized Enrichment Score (NES) | -2.3520203 |
| Nominal p-value | 0.0 |
| FDR q-value | 1.3335656E-4 |
| FWER p-Value | 0.002 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | E2F5 | ENSG00000133740.11 | 2048 | 0.699 | 0.0087 | No | ||
| 2 | TFDP2 | ENSG00000114126.17 | 15564 | 0.157 | -0.3067 | No | ||
| 3 | CCNA1 | ENSG00000133101.10 | 17734 | 0.098 | -0.3512 | No | ||
| 4 | RBBP4 | ENSG00000162521.19 | 18441 | 0.081 | -0.3616 | No | ||
| 5 | E2F4 | ENSG00000205250.9 | 19102 | 0.062 | -0.3725 | No | ||
| 6 | RBL2 | ENSG00000103479.16 | 20946 | 0.014 | -0.4161 | No | ||
| 7 | LIN37 | ENSG00000267796.8 | 23851 | -0.062 | -0.4816 | No | ||
| 8 | HDAC1 | ENSG00000116478.12 | 26306 | -0.129 | -0.5304 | No | ||
| 9 | POLA1 | ENSG00000101868.11 | 26537 | -0.136 | -0.5246 | No | ||
| 10 | E2F6 | ENSG00000169016.17 | 28829 | -0.206 | -0.5631 | No | ||
| 11 | LIN54 | ENSG00000189308.11 | 30719 | -0.267 | -0.5867 | No | ||
| 12 | CCNE1 | ENSG00000105173.14 | 32197 | -0.305 | -0.5971 | No | ||
| 13 | LIN52 | ENSG00000205659.10 | 32727 | -0.325 | -0.5828 | No | ||
| 14 | TFDP1 | ENSG00000198176.13 | 35512 | -0.389 | -0.6179 | Yes | ||
| 15 | CDT1 | ENSG00000167513.9 | 35789 | -0.401 | -0.5910 | Yes | ||
| 16 | TK1 | ENSG00000167900.12 | 36493 | -0.426 | -0.5725 | Yes | ||
| 17 | PCNA | ENSG00000132646.11 | 37166 | -0.461 | -0.5502 | Yes | ||
| 18 | ORC1 | ENSG00000085840.13 | 37179 | -0.462 | -0.5118 | Yes | ||
| 19 | LIN9 | ENSG00000183814.15 | 37237 | -0.466 | -0.4742 | Yes | ||
| 20 | RBL1 | ENSG00000080839.12 | 37521 | -0.487 | -0.4403 | Yes | ||
| 21 | FBXO5 | ENSG00000112029.10 | 37782 | -0.511 | -0.4039 | Yes | ||
| 22 | E2F1 | ENSG00000101412.13 | 38085 | -0.533 | -0.3666 | Yes | ||
| 23 | CDC45 | ENSG00000093009.10 | 38822 | -0.583 | -0.3357 | Yes | ||
| 24 | CDK1 | ENSG00000170312.16 | 39453 | -0.632 | -0.2982 | Yes | ||
| 25 | RRM2 | ENSG00000171848.15 | 39983 | -0.710 | -0.2517 | Yes | ||
| 26 | CDC6 | ENSG00000094804.12 | 40060 | -0.723 | -0.1930 | Yes | ||
| 27 | CDC25A | ENSG00000164045.12 | 40263 | -0.768 | -0.1337 | Yes | ||
| 28 | TYMS | ENSG00000176890.16 | 40602 | -0.877 | -0.0685 | Yes | ||
| 29 | DHFR | ENSG00000228716.7 | 40826 | -0.981 | 0.0081 | Yes |
