Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT |
| Enrichment Score (ES) | -0.45917264 |
| Normalized Enrichment Score (NES) | -2.283536 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.8747105E-4 |
| FWER p-Value | 0.006 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PLA2G6 | ENSG00000184381.20 | 1918 | 0.714 | -0.0310 | No | ||
| 2 | KIF12 | ENSG00000136883.14 | 2094 | 0.694 | -0.0201 | No | ||
| 3 | KIF19 | ENSG00000196169.15 | 3593 | 0.563 | -0.0442 | No | ||
| 4 | KIF5A | ENSG00000155980.12 | 3665 | 0.560 | -0.0336 | No | ||
| 5 | PLA2G4A | ENSG00000116711.10 | 4587 | 0.514 | -0.0448 | No | ||
| 6 | KIFC2 | ENSG00000167702.12 | 5026 | 0.489 | -0.0447 | No | ||
| 7 | KIF26A | ENSG00000066735.14 | 5366 | 0.467 | -0.0427 | No | ||
| 8 | KIF16B | ENSG00000089177.18 | 5681 | 0.449 | -0.0405 | No | ||
| 9 | KIF21B | ENSG00000116852.14 | 5815 | 0.443 | -0.0340 | No | ||
| 10 | KIF26B | ENSG00000162849.16 | 5972 | 0.435 | -0.0283 | No | ||
| 11 | KLC4 | ENSG00000137171.15 | 6556 | 0.406 | -0.0336 | No | ||
| 12 | DYNC1I1 | ENSG00000158560.14 | 7076 | 0.386 | -0.0377 | No | ||
| 13 | ARFGAP1 | ENSG00000101199.13 | 7678 | 0.364 | -0.0444 | No | ||
| 14 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.0475 | No | ||
| 15 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.1033 | No | ||
| 16 | USE1 | ENSG00000053501.13 | 12070 | 0.268 | -0.1310 | No | ||
| 17 | KIF1A | ENSG00000130294.16 | 12289 | 0.261 | -0.1306 | No | ||
| 18 | NAPB | ENSG00000125814.17 | 13487 | 0.222 | -0.1549 | No | ||
| 19 | KLC1 | ENSG00000126214.21 | 14819 | 0.180 | -0.1833 | No | ||
| 20 | AC027237.1 | ENSG00000259191.2 | 15280 | 0.165 | -0.1909 | No | ||
| 21 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.1955 | No | ||
| 22 | ARFGAP2 | ENSG00000149182.15 | 17482 | 0.104 | -0.2388 | No | ||
| 23 | TMED9 | ENSG00000184840.12 | 18711 | 0.073 | -0.2671 | No | ||
| 24 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.2800 | No | ||
| 25 | KDELR1 | ENSG00000105438.9 | 19315 | 0.056 | -0.2793 | No | ||
| 26 | KIF25 | ENSG00000125337.19 | 21057 | 0.010 | -0.3216 | No | ||
| 27 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.3270 | No | ||
| 28 | NAPG | ENSG00000134265.13 | 21412 | 0.001 | -0.3300 | No | ||
| 29 | ARF5 | ENSG00000004059.11 | 21663 | -0.006 | -0.3360 | No | ||
| 30 | KLC2 | ENSG00000174996.11 | 22207 | -0.018 | -0.3488 | No | ||
| 31 | AGPAT3 | ENSG00000160216.19 | 22294 | -0.021 | -0.3505 | No | ||
| 32 | TMED2 | ENSG00000086598.11 | 22331 | -0.022 | -0.3509 | No | ||
| 33 | RAB6B | ENSG00000154917.11 | 22675 | -0.030 | -0.3586 | No | ||
| 34 | KDELR3 | ENSG00000100196.11 | 22740 | -0.032 | -0.3594 | No | ||
| 35 | DCTN3 | ENSG00000137100.16 | 22796 | -0.033 | -0.3601 | No | ||
| 36 | KIF9 | ENSG00000088727.12 | 22944 | -0.037 | -0.3628 | No | ||
| 37 | ARF1 | ENSG00000143761.16 | 23029 | -0.040 | -0.3640 | No | ||
| 38 | GALNT1 | ENSG00000141429.13 | 23031 | -0.040 | -0.3631 | No | ||
| 39 | GALNT2 | ENSG00000143641.10 | 23333 | -0.048 | -0.3694 | No | ||
| 40 | DYNLL2 | ENSG00000264364.3 | 23336 | -0.048 | -0.3684 | No | ||
| 41 | SURF4 | ENSG00000148248.14 | 23692 | -0.058 | -0.3758 | No | ||
| 42 | COPE | ENSG00000105669.14 | 23839 | -0.062 | -0.3780 | No | ||
| 43 | BICD1 | ENSG00000151746.14 | 23875 | -0.062 | -0.3775 | No | ||
| 44 | KIF27 | ENSG00000165115.15 | 24228 | -0.071 | -0.3845 | No | ||
| 45 | PAFAH1B3 | ENSG00000079462.7 | 24885 | -0.088 | -0.3985 | No | ||
| 46 | TMED3 | ENSG00000166557.13 | 25030 | -0.093 | -0.4000 | No | ||
| 47 | COPA | ENSG00000122218.16 | 25255 | -0.097 | -0.4033 | No | ||
| 48 | DYNC1LI2 | ENSG00000135720.13 | 25352 | -0.101 | -0.4035 | No | ||
| 49 | NAPA | ENSG00000105402.8 | 26346 | -0.131 | -0.4248 | No | ||
| 50 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.4264 | No | ||
| 51 | ARF3 | ENSG00000134287.10 | 26805 | -0.144 | -0.4298 | No | ||
| 52 | STX18 | ENSG00000168818.10 | 26910 | -0.147 | -0.4291 | No | ||
| 53 | KDELR2 | ENSG00000136240.10 | 26978 | -0.149 | -0.4275 | No | ||
| 54 | NBAS | ENSG00000151779.13 | 27131 | -0.153 | -0.4278 | No | ||
| 55 | RINT1 | ENSG00000135249.8 | 27607 | -0.168 | -0.4357 | No | ||
| 56 | KIFAP3 | ENSG00000075945.13 | 27710 | -0.171 | -0.4344 | No | ||
| 57 | RAB1B | ENSG00000174903.16 | 27815 | -0.174 | -0.4331 | No | ||
| 58 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.4296 | No | ||
| 59 | KIF21A | ENSG00000139116.18 | 27919 | -0.177 | -0.4279 | No | ||
| 60 | COPZ1 | ENSG00000111481.10 | 28332 | -0.190 | -0.4337 | No | ||
| 61 | RAB3GAP2 | ENSG00000118873.16 | 28368 | -0.192 | -0.4304 | No | ||
| 62 | DCTN4 | ENSG00000132912.12 | 28497 | -0.197 | -0.4292 | No | ||
| 63 | SEC22B | ENSG00000265808.4 | 29171 | -0.217 | -0.4408 | No | ||
| 64 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.4398 | No | ||
| 65 | RAB18 | ENSG00000099246.16 | 30126 | -0.248 | -0.4537 | Yes | ||
| 66 | RAB1A | ENSG00000138069.18 | 30150 | -0.249 | -0.4488 | Yes | ||
| 67 | GBF1 | ENSG00000107862.4 | 30343 | -0.255 | -0.4479 | Yes | ||
| 68 | TMED10 | ENSG00000170348.9 | 30459 | -0.259 | -0.4450 | Yes | ||
| 69 | BICD2 | ENSG00000185963.14 | 30528 | -0.260 | -0.4409 | Yes | ||
| 70 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.4397 | Yes | ||
| 71 | COPG1 | ENSG00000181789.14 | 30735 | -0.267 | -0.4342 | Yes | ||
| 72 | ARFGAP3 | ENSG00000242247.11 | 30822 | -0.270 | -0.4304 | Yes | ||
| 73 | ZW10 | ENSG00000086827.9 | 30856 | -0.271 | -0.4252 | Yes | ||
| 74 | KIF22 | ENSG00000079616.12 | 30925 | -0.274 | -0.4208 | Yes | ||
| 75 | DCTN5 | ENSG00000166847.10 | 31044 | -0.279 | -0.4176 | Yes | ||
| 76 | KIF3C | ENSG00000084731.15 | 31061 | -0.279 | -0.4119 | Yes | ||
| 77 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.4067 | Yes | ||
| 78 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.4178 | Yes | ||
| 79 | COPB2 | ENSG00000184432.10 | 32009 | -0.297 | -0.4158 | Yes | ||
| 80 | DCTN2 | ENSG00000175203.15 | 32923 | -0.333 | -0.4307 | Yes | ||
| 81 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.4297 | Yes | ||
| 82 | PAFAH1B2 | ENSG00000168092.14 | 34182 | -0.349 | -0.4463 | Yes | ||
| 83 | KIF1C | ENSG00000129250.12 | 34212 | -0.350 | -0.4394 | Yes | ||
| 84 | KIF1B | ENSG00000054523.17 | 34654 | -0.354 | -0.4423 | Yes | ||
| 85 | KIF3A | ENSG00000131437.15 | 35070 | -0.368 | -0.4444 | Yes | ||
| 86 | TMED7 | ENSG00000134970.14 | 35148 | -0.371 | -0.4381 | Yes | ||
| 87 | CAPZB | ENSG00000077549.18 | 35414 | -0.384 | -0.4361 | Yes | ||
| 88 | RAB6A | ENSG00000175582.19 | 35427 | -0.385 | -0.4279 | Yes | ||
| 89 | RAB3GAP1 | ENSG00000115839.17 | 35438 | -0.385 | -0.4197 | Yes | ||
| 90 | DCTN1 | ENSG00000204843.12 | 35697 | -0.397 | -0.4173 | Yes | ||
| 91 | KIF20A | ENSG00000112984.12 | 35970 | -0.404 | -0.4150 | Yes | ||
| 92 | PAFAH1B1 | ENSG00000007168.13 | 36076 | -0.408 | -0.4086 | Yes | ||
| 93 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.4014 | Yes | ||
| 94 | DCTN6 | ENSG00000104671.8 | 36330 | -0.417 | -0.3965 | Yes | ||
| 95 | NSF | ENSG00000073969.18 | 36513 | -0.428 | -0.3916 | Yes | ||
| 96 | ARCN1 | ENSG00000095139.14 | 36550 | -0.430 | -0.3830 | Yes | ||
| 97 | COPB1 | ENSG00000129083.12 | 36728 | -0.437 | -0.3777 | Yes | ||
| 98 | KIF2C | ENSG00000142945.13 | 36852 | -0.443 | -0.3710 | Yes | ||
| 99 | KIF18B | ENSG00000186185.14 | 36892 | -0.446 | -0.3622 | Yes | ||
| 100 | ACTR1A | ENSG00000138107.13 | 36970 | -0.450 | -0.3541 | Yes | ||
| 101 | KIF2A | ENSG00000068796.16 | 36994 | -0.452 | -0.3448 | Yes | ||
| 102 | BNIP1 | ENSG00000113734.17 | 37050 | -0.455 | -0.3361 | Yes | ||
| 103 | KIF13B | ENSG00000197892.13 | 37199 | -0.463 | -0.3295 | Yes | ||
| 104 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3242 | Yes | ||
| 105 | ARF4 | ENSG00000168374.11 | 37528 | -0.487 | -0.3163 | Yes | ||
| 106 | KIF4A | ENSG00000090889.12 | 37615 | -0.495 | -0.3075 | Yes | ||
| 107 | KIF3B | ENSG00000101350.8 | 37801 | -0.512 | -0.3008 | Yes | ||
| 108 | CAPZA2 | ENSG00000198898.14 | 38185 | -0.541 | -0.2982 | Yes | ||
| 109 | KIF15 | ENSG00000163808.17 | 38204 | -0.543 | -0.2867 | Yes | ||
| 110 | DYNC1LI1 | ENSG00000144635.9 | 38271 | -0.548 | -0.2763 | Yes | ||
| 111 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2652 | Yes | ||
| 112 | KIFC1 | ENSG00000237649.8 | 38364 | -0.556 | -0.2541 | Yes | ||
| 113 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2475 | Yes | ||
| 114 | COPZ2 | ENSG00000005243.10 | 39066 | -0.608 | -0.2455 | Yes | ||
| 115 | CAPZA1 | ENSG00000116489.13 | 39314 | -0.624 | -0.2378 | Yes | ||
| 116 | ACTR10 | ENSG00000131966.14 | 39413 | -0.627 | -0.2264 | Yes | ||
| 117 | RACGAP1 | ENSG00000161800.13 | 39469 | -0.633 | -0.2139 | Yes | ||
| 118 | KIF4B | ENSG00000226650.6 | 39776 | -0.670 | -0.2066 | Yes | ||
| 119 | KIF6 | ENSG00000164627.18 | 39943 | -0.703 | -0.1952 | Yes | ||
| 120 | COPG2 | ENSG00000158623.14 | 40017 | -0.716 | -0.1813 | Yes | ||
| 121 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.1673 | Yes | ||
| 122 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.1512 | Yes | ||
| 123 | CENPE | ENSG00000138778.12 | 40145 | -0.740 | -0.1358 | Yes | ||
| 124 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.1219 | Yes | ||
| 125 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.1093 | Yes | ||
| 126 | KIF11 | ENSG00000138160.6 | 40519 | -0.845 | -0.0909 | Yes | ||
| 127 | KLC3 | ENSG00000104892.17 | 40542 | -0.855 | -0.0726 | Yes | ||
| 128 | KIF5B | ENSG00000170759.11 | 40785 | -0.954 | -0.0576 | Yes | ||
| 129 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | -0.0368 | Yes | ||
| 130 | KIF20B | ENSG00000138182.14 | 40873 | -1.017 | -0.0158 | Yes | ||
| 131 | KIF18A | ENSG00000121621.7 | 40921 | -1.038 | 0.0058 | Yes |
