Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS |
| Enrichment Score (ES) | -0.4705494 |
| Normalized Enrichment Score (NES) | -2.3685346 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.963224E-5 |
| FWER p-Value | 0.001 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | APOBEC3G | ENSG00000239713.9 | 1720 | 0.745 | -0.0177 | No | ||
| 2 | ELMO1 | ENSG00000155849.15 | 2805 | 0.622 | -0.0238 | No | ||
| 3 | HLA-A | ENSG00000206503.13 | 8022 | 0.360 | -0.1392 | No | ||
| 4 | LCK | ENSG00000182866.17 | 11848 | 0.276 | -0.2234 | No | ||
| 5 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2706 | No | ||
| 6 | HCK | ENSG00000101336.14 | 14377 | 0.195 | -0.2720 | No | ||
| 7 | AAAS | ENSG00000094914.14 | 15362 | 0.163 | -0.2907 | No | ||
| 8 | RANGAP1 | ENSG00000100401.19 | 15733 | 0.152 | -0.2948 | No | ||
| 9 | CD247 | ENSG00000198821.10 | 15755 | 0.152 | -0.2903 | No | ||
| 10 | POM121C | ENSG00000272391.6 | 16628 | 0.128 | -0.3074 | No | ||
| 11 | POM121 | ENSG00000196313.11 | 17139 | 0.114 | -0.3161 | No | ||
| 12 | HMGA1 | ENSG00000137309.19 | 18018 | 0.090 | -0.3346 | No | ||
| 13 | NUP160 | ENSG00000030066.13 | 18845 | 0.069 | -0.3525 | No | ||
| 14 | NUP214 | ENSG00000126883.17 | 19230 | 0.059 | -0.3599 | No | ||
| 15 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.3591 | No | ||
| 16 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.3604 | No | ||
| 17 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.3627 | No | ||
| 18 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.3705 | No | ||
| 19 | NUP43 | ENSG00000120253.14 | 20047 | 0.038 | -0.3719 | No | ||
| 20 | NPM1 | ENSG00000181163.13 | 20296 | 0.031 | -0.3770 | No | ||
| 21 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.3889 | No | ||
| 22 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.3918 | No | ||
| 23 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.3921 | No | ||
| 24 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.3955 | No | ||
| 25 | CDK9 | ENSG00000136807.14 | 21197 | 0.007 | -0.3969 | No | ||
| 26 | NUP35 | ENSG00000163002.13 | 21253 | 0.005 | -0.3981 | No | ||
| 27 | NUP62 | ENSG00000213024.11 | 21980 | -0.014 | -0.4153 | No | ||
| 28 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.4188 | No | ||
| 29 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.4208 | No | ||
| 30 | SEC13 | ENSG00000157020.18 | 22468 | -0.026 | -0.4251 | No | ||
| 31 | BANF1 | ENSG00000175334.8 | 22894 | -0.036 | -0.4343 | No | ||
| 32 | B2M | ENSG00000166710.20 | 22947 | -0.038 | -0.4344 | No | ||
| 33 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4344 | No | ||
| 34 | ARF1 | ENSG00000143761.16 | 23029 | -0.040 | -0.4337 | No | ||
| 35 | RAE1 | ENSG00000101146.13 | 23056 | -0.041 | -0.4330 | No | ||
| 36 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4318 | No | ||
| 37 | AP2S1 | ENSG00000042753.11 | 23077 | -0.042 | -0.4308 | No | ||
| 38 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4355 | No | ||
| 39 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4342 | No | ||
| 40 | SEH1L | ENSG00000085415.16 | 23768 | -0.059 | -0.4425 | No | ||
| 41 | CCNT1 | ENSG00000129315.11 | 24047 | -0.066 | -0.4471 | No | ||
| 42 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4493 | No | ||
| 43 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.4593 | No | ||
| 44 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.4576 | No | ||
| 45 | NUP133 | ENSG00000069248.12 | 24802 | -0.086 | -0.4548 | No | ||
| 46 | NUP54 | ENSG00000138750.15 | 25127 | -0.094 | -0.4596 | No | ||
| 47 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.4657 | No | ||
| 48 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.4669 | Yes | ||
| 49 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.4655 | Yes | ||
| 50 | BTRC | ENSG00000166167.18 | 25965 | -0.119 | -0.4653 | Yes | ||
| 51 | ELOB | ENSG00000103363.14 | 25982 | -0.120 | -0.4618 | Yes | ||
| 52 | PSIP1 | ENSG00000164985.15 | 26088 | -0.123 | -0.4603 | Yes | ||
| 53 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.4594 | Yes | ||
| 54 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.4574 | Yes | ||
| 55 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.4535 | Yes | ||
| 56 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.4523 | Yes | ||
| 57 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.4482 | Yes | ||
| 58 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.4485 | Yes | ||
| 59 | NUP58 | ENSG00000139496.16 | 26686 | -0.140 | -0.4444 | Yes | ||
| 60 | CD8B | ENSG00000172116.23 | 26744 | -0.142 | -0.4411 | Yes | ||
| 61 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.4382 | Yes | ||
| 62 | AP2M1 | ENSG00000161203.13 | 26819 | -0.144 | -0.4335 | Yes | ||
| 63 | NUP107 | ENSG00000111581.10 | 26867 | -0.145 | -0.4299 | Yes | ||
| 64 | CUL5 | ENSG00000166266.14 | 27037 | -0.150 | -0.4292 | Yes | ||
| 65 | TPR | ENSG00000047410.14 | 27114 | -0.153 | -0.4260 | Yes | ||
| 66 | AP2A1 | ENSG00000196961.12 | 27276 | -0.157 | -0.4249 | Yes | ||
| 67 | AP2A2 | ENSG00000183020.13 | 27410 | -0.161 | -0.4228 | Yes | ||
| 68 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.4225 | Yes | ||
| 69 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.4192 | Yes | ||
| 70 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.4147 | Yes | ||
| 71 | NUP85 | ENSG00000125450.11 | 27774 | -0.173 | -0.4093 | Yes | ||
| 72 | NUP188 | ENSG00000095319.14 | 27939 | -0.178 | -0.4075 | Yes | ||
| 73 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4021 | Yes | ||
| 74 | NUP98 | ENSG00000110713.17 | 28185 | -0.186 | -0.4016 | Yes | ||
| 75 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.4011 | Yes | ||
| 76 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.3954 | Yes | ||
| 77 | NUP88 | ENSG00000108559.12 | 28505 | -0.197 | -0.3903 | Yes | ||
| 78 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.3867 | Yes | ||
| 79 | SKP1 | ENSG00000113558.18 | 28827 | -0.206 | -0.3849 | Yes | ||
| 80 | NUP153 | ENSG00000124789.11 | 29336 | -0.222 | -0.3900 | Yes | ||
| 81 | PACS1 | ENSG00000175115.12 | 29524 | -0.228 | -0.3871 | Yes | ||
| 82 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.3908 | Yes | ||
| 83 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.3853 | Yes | ||
| 84 | AP1G1 | ENSG00000166747.12 | 30442 | -0.258 | -0.3850 | Yes | ||
| 85 | RANBP1 | ENSG00000099901.17 | 30689 | -0.265 | -0.3824 | Yes | ||
| 86 | NUP210 | ENSG00000132182.12 | 31109 | -0.281 | -0.3834 | Yes | ||
| 87 | PSMA8 | ENSG00000154611.14 | 31324 | -0.285 | -0.3794 | Yes | ||
| 88 | SLC25A5 | ENSG00000005022.6 | 31924 | -0.294 | -0.3844 | Yes | ||
| 89 | KPNB1 | ENSG00000108424.10 | 31990 | -0.296 | -0.3764 | Yes | ||
| 90 | NUP93 | ENSG00000102900.13 | 32074 | -0.299 | -0.3686 | Yes | ||
| 91 | NUP155 | ENSG00000113569.16 | 32287 | -0.309 | -0.3638 | Yes | ||
| 92 | SLC25A4 | ENSG00000151729.11 | 32397 | -0.314 | -0.3562 | Yes | ||
| 93 | RBX1 | ENSG00000100387.9 | 32483 | -0.316 | -0.3480 | Yes | ||
| 94 | RANBP2 | ENSG00000153201.16 | 32550 | -0.318 | -0.3392 | Yes | ||
| 95 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.3322 | Yes | ||
| 96 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.3230 | Yes | ||
| 97 | AP1B1 | ENSG00000100280.16 | 34073 | -0.344 | -0.3439 | Yes | ||
| 98 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.3555 | Yes | ||
| 99 | NDC1 | ENSG00000058804.12 | 35259 | -0.376 | -0.3486 | Yes | ||
| 100 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.3371 | Yes | ||
| 101 | ATP6V1H | ENSG00000047249.18 | 35368 | -0.382 | -0.3264 | Yes | ||
| 102 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.3154 | Yes | ||
| 103 | NUP37 | ENSG00000075188.9 | 35611 | -0.394 | -0.3070 | Yes | ||
| 104 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.2948 | Yes | ||
| 105 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.2891 | Yes | ||
| 106 | AP2B1 | ENSG00000006125.18 | 35998 | -0.406 | -0.2771 | Yes | ||
| 107 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.2736 | Yes | ||
| 108 | NUP205 | ENSG00000155561.15 | 36490 | -0.426 | -0.2615 | Yes | ||
| 109 | AP1S1 | ENSG00000106367.15 | 36495 | -0.426 | -0.2477 | Yes | ||
| 110 | RAN | ENSG00000132341.12 | 36507 | -0.427 | -0.2340 | Yes | ||
| 111 | DOCK2 | ENSG00000134516.17 | 36842 | -0.442 | -0.2278 | Yes | ||
| 112 | PAK2 | ENSG00000180370.10 | 36983 | -0.451 | -0.2165 | Yes | ||
| 113 | PPIA | ENSG00000196262.14 | 37055 | -0.456 | -0.2034 | Yes | ||
| 114 | KPNA1 | ENSG00000114030.13 | 37126 | -0.459 | -0.1901 | Yes | ||
| 115 | RCC1 | ENSG00000180198.16 | 37211 | -0.464 | -0.1771 | Yes | ||
| 116 | XPO1 | ENSG00000082898.17 | 37227 | -0.465 | -0.1623 | Yes | ||
| 117 | RAC1 | ENSG00000136238.18 | 37298 | -0.471 | -0.1487 | Yes | ||
| 118 | AP1S3 | ENSG00000152056.17 | 37559 | -0.489 | -0.1390 | Yes | ||
| 119 | NUP50 | ENSG00000093000.19 | 37691 | -0.501 | -0.1259 | Yes | ||
| 120 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.1103 | Yes | ||
| 121 | ELOC | ENSG00000154582.16 | 37865 | -0.517 | -0.0968 | Yes | ||
| 122 | FYN | ENSG00000010810.17 | 37878 | -0.518 | -0.0802 | Yes | ||
| 123 | PSME4 | ENSG00000068878.15 | 38072 | -0.532 | -0.0676 | Yes | ||
| 124 | AP1M1 | ENSG00000072958.8 | 38869 | -0.587 | -0.0679 | Yes | ||
| 125 | CD28 | ENSG00000178562.18 | 39168 | -0.615 | -0.0551 | Yes | ||
| 126 | AP1S2 | ENSG00000182287.15 | 39189 | -0.618 | -0.0355 | Yes | ||
| 127 | CD4 | ENSG00000010610.10 | 39926 | -0.700 | -0.0307 | Yes | ||
| 128 | AP1M2 | ENSG00000129354.11 | 40522 | -0.847 | -0.0176 | Yes | ||
| 129 | PSMB11 | ENSG00000222028.5 | 40874 | -1.018 | 0.0070 | Yes |
