Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR |
| Enrichment Score (ES) | -0.527948 |
| Normalized Enrichment Score (NES) | -2.2413993 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.8170384E-4 |
| FWER p-Value | 0.009 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AR | ENSG00000169083.17 | 5886 | 0.439 | -0.1213 | No | ||
| 2 | DYNC1I1 | ENSG00000158560.14 | 7076 | 0.386 | -0.1310 | No | ||
| 3 | TUBB1 | ENSG00000101162.3 | 8127 | 0.356 | -0.1387 | No | ||
| 4 | FKBP5 | ENSG00000096060.14 | 8892 | 0.340 | -0.1404 | No | ||
| 5 | TUBA3D | ENSG00000075886.11 | 10693 | 0.303 | -0.1691 | No | ||
| 6 | NR3C2 | ENSG00000151623.15 | 12809 | 0.244 | -0.2083 | No | ||
| 7 | TUBB3 | ENSG00000258947.7 | 15608 | 0.156 | -0.2686 | No | ||
| 8 | HSPA2 | ENSG00000126803.9 | 16949 | 0.118 | -0.2953 | No | ||
| 9 | DNAJA4 | ENSG00000140403.12 | 17651 | 0.100 | -0.3074 | No | ||
| 10 | TUBA4B | ENSG00000243910.8 | 19289 | 0.057 | -0.3444 | No | ||
| 11 | TUBA4A | ENSG00000127824.14 | 21284 | 0.004 | -0.3927 | No | ||
| 12 | DCTN3 | ENSG00000137100.16 | 22796 | -0.033 | -0.4278 | No | ||
| 13 | DYNLL2 | ENSG00000264364.3 | 23336 | -0.048 | -0.4385 | No | ||
| 14 | HSPA1B | ENSG00000204388.7 | 24750 | -0.084 | -0.4687 | No | ||
| 15 | DYNC1LI2 | ENSG00000135720.13 | 25352 | -0.101 | -0.4783 | No | ||
| 16 | TUBA8 | ENSG00000183785.15 | 26534 | -0.136 | -0.5002 | No | ||
| 17 | PGR | ENSG00000082175.15 | 27674 | -0.170 | -0.5195 | Yes | ||
| 18 | TUBA3C | ENSG00000198033.12 | 27829 | -0.175 | -0.5145 | Yes | ||
| 19 | HSPA1L | ENSG00000204390.10 | 27981 | -0.180 | -0.5092 | Yes | ||
| 20 | DNAJA2 | ENSG00000069345.12 | 28473 | -0.195 | -0.5114 | Yes | ||
| 21 | DCTN4 | ENSG00000132912.12 | 28497 | -0.197 | -0.5022 | Yes | ||
| 22 | HSP90AB1 | ENSG00000096384.20 | 28800 | -0.205 | -0.4993 | Yes | ||
| 23 | TUBA3E | ENSG00000152086.9 | 29330 | -0.222 | -0.5011 | Yes | ||
| 24 | PTGES3 | ENSG00000110958.16 | 30197 | -0.250 | -0.5097 | Yes | ||
| 25 | TUBB8 | ENSG00000261456.5 | 30717 | -0.267 | -0.5090 | Yes | ||
| 26 | FKBP4 | ENSG00000004478.8 | 30809 | -0.270 | -0.4978 | Yes | ||
| 27 | DCTN5 | ENSG00000166847.10 | 31044 | -0.279 | -0.4896 | Yes | ||
| 28 | TUBB4A | ENSG00000104833.12 | 31106 | -0.281 | -0.4770 | Yes | ||
| 29 | DYNC1H1 | ENSG00000197102.12 | 31822 | -0.290 | -0.4800 | Yes | ||
| 30 | DNAJA1 | ENSG00000086061.16 | 32115 | -0.301 | -0.4721 | Yes | ||
| 31 | DCTN2 | ENSG00000175203.15 | 32923 | -0.333 | -0.4751 | Yes | ||
| 32 | TUBAL3 | ENSG00000178462.12 | 33185 | -0.336 | -0.4647 | Yes | ||
| 33 | CAPZB | ENSG00000077549.18 | 35414 | -0.384 | -0.4997 | Yes | ||
| 34 | HSPA1A | ENSG00000204389.10 | 35629 | -0.395 | -0.4852 | Yes | ||
| 35 | DCTN1 | ENSG00000204843.12 | 35697 | -0.397 | -0.4671 | Yes | ||
| 36 | STIP1 | ENSG00000168439.16 | 35973 | -0.404 | -0.4536 | Yes | ||
| 37 | DYNC1I2 | ENSG00000077380.15 | 36153 | -0.411 | -0.4374 | Yes | ||
| 38 | DCTN6 | ENSG00000104671.8 | 36330 | -0.417 | -0.4209 | Yes | ||
| 39 | ACTR1A | ENSG00000138107.13 | 36970 | -0.450 | -0.4140 | Yes | ||
| 40 | DNAJB1 | ENSG00000132002.8 | 37147 | -0.460 | -0.3953 | Yes | ||
| 41 | TUBA1B | ENSG00000123416.15 | 37411 | -0.478 | -0.3779 | Yes | ||
| 42 | HSP90AA1 | ENSG00000080824.18 | 37823 | -0.514 | -0.3622 | Yes | ||
| 43 | HSPA8 | ENSG00000109971.14 | 37882 | -0.519 | -0.3378 | Yes | ||
| 44 | CAPZA2 | ENSG00000198898.14 | 38185 | -0.541 | -0.3181 | Yes | ||
| 45 | DYNC1LI1 | ENSG00000144635.9 | 38271 | -0.548 | -0.2929 | Yes | ||
| 46 | DYNLL1 | ENSG00000088986.11 | 38317 | -0.554 | -0.2664 | Yes | ||
| 47 | TUBA1A | ENSG00000167552.14 | 38598 | -0.561 | -0.2452 | Yes | ||
| 48 | CAPZA1 | ENSG00000116489.13 | 39314 | -0.624 | -0.2315 | Yes | ||
| 49 | ACTR10 | ENSG00000131966.14 | 39413 | -0.627 | -0.2026 | Yes | ||
| 50 | TUBB4B | ENSG00000188229.6 | 40106 | -0.733 | -0.1829 | Yes | ||
| 51 | TUBB2B | ENSG00000137285.10 | 40109 | -0.733 | -0.1464 | Yes | ||
| 52 | TUBB2A | ENSG00000137267.6 | 40266 | -0.768 | -0.1119 | Yes | ||
| 53 | TUBA1C | ENSG00000167553.15 | 40512 | -0.843 | -0.0758 | Yes | ||
| 54 | NR3C1 | ENSG00000113580.15 | 40550 | -0.857 | -0.0340 | Yes | ||
| 55 | TUBB6 | ENSG00000176014.13 | 40817 | -0.979 | 0.0084 | Yes |
