Details for gene set REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT[GSEA]

Table: GSEA Results Summary

Dataset	Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Phenotype	Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH
Upregulated in class	FSHD2
GeneSet	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
Enrichment Score (ES)	0.5726575
Normalized Enrichment Score (NES)	1.8398117
Nominal p-value	0.0017482517
FDR q-value	0.06964899
FWER p-Value	0.736

Fig 1: Enrichment plot: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]

	PROBE	DESCRIPTION (from dataset)	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	C1S	ENSG00000182326.15			1233	0.811	0.0648	Yes
2	C4A	ENSG00000244731.8			2677	0.636	0.1040	Yes
3	COLEC11	ENSG00000118004.17			2760	0.627	0.1753	Yes
4	C1R	ENSG00000159403.18			2987	0.607	0.2407	Yes
5	CFP	ENSG00000126759.13			3748	0.554	0.2869	Yes
6	MASP2	ENSG00000009724.17			4725	0.509	0.3226	Yes
7	CFB	ENSG00000243649.8			4800	0.504	0.3797	Yes
8	CFD	ENSG00000197766.8			6918	0.393	0.3742	Yes
9	FCN1	ENSG00000085265.11			7665	0.364	0.3986	Yes
10	IGLV1-51	ENSG00000211644.3			7791	0.363	0.4379	Yes
11	IGLV3-1	ENSG00000211673.2			7856	0.362	0.4787	Yes
12	COLEC10	ENSG00000184374.3			8219	0.353	0.5111	Yes
13	GZMM	ENSG00000197540.8			9204	0.327	0.5253	Yes
14	MBL2	ENSG00000165471.6			9409	0.319	0.5576	Yes
15	CRP	ENSG00000132693.12			10259	0.305	0.5727	Yes
16	C3	ENSG00000125730.17			13115	0.235	0.5307	No
17	MASP1	ENSG00000127241.16			13988	0.206	0.5336	No
18	C2	ENSG00000166278.15			16704	0.125	0.4822	No
19	FCN3	ENSG00000142748.12			21773	-0.008	0.3600	No
20	IGLC2	ENSG00000211677.2			22079	-0.016	0.3544	No
21	C4B	ENSG00000224389.9			28524	-0.197	0.2208	No
22	C1QB	ENSG00000173369.16			33116	-0.336	0.1485	No
23	C1QA	ENSG00000173372.17			35837	-0.402	0.1294	No

Fig 2: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT: Random ES distribution   
Gene set null distribution of ES for REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT