Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Normalized.Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Phenotype | Phenotype.FSHD2.ARH.cls#FSHD2_versus_ARH |
| Upregulated in class | ARH |
| GeneSet | REACTOME_MITOTIC_G1_G1_S_PHASES |
| Enrichment Score (ES) | -0.49432883 |
| Normalized Enrichment Score (NES) | -2.5293176 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDKN1C | ENSG00000129757.13 | 1596 | 0.759 | -0.0224 | No | ||
| 2 | E2F5 | ENSG00000133740.11 | 2048 | 0.699 | -0.0182 | No | ||
| 3 | CDKN2B | ENSG00000147883.12 | 2601 | 0.644 | -0.0177 | No | ||
| 4 | ABL1 | ENSG00000097007.19 | 3251 | 0.588 | -0.0208 | No | ||
| 5 | CDKN1B | ENSG00000111276.11 | 4380 | 0.521 | -0.0370 | No | ||
| 6 | CCND2 | ENSG00000118971.8 | 4862 | 0.500 | -0.0378 | No | ||
| 7 | PSMB8 | ENSG00000204264.11 | 14058 | 0.204 | -0.2576 | No | ||
| 8 | POLE4 | ENSG00000115350.12 | 15368 | 0.163 | -0.2860 | No | ||
| 9 | TFDP2 | ENSG00000114126.17 | 15564 | 0.157 | -0.2873 | No | ||
| 10 | PTK6 | ENSG00000101213.7 | 16081 | 0.143 | -0.2968 | No | ||
| 11 | RPA2 | ENSG00000117748.10 | 16945 | 0.118 | -0.3153 | No | ||
| 12 | MCM7 | ENSG00000166508.17 | 17495 | 0.104 | -0.3264 | No | ||
| 13 | CCNA1 | ENSG00000133101.10 | 17734 | 0.098 | -0.3301 | No | ||
| 14 | AKT2 | ENSG00000105221.18 | 18110 | 0.088 | -0.3373 | No | ||
| 15 | LYN | ENSG00000254087.8 | 18130 | 0.087 | -0.3359 | No | ||
| 16 | RBBP4 | ENSG00000162521.19 | 18441 | 0.081 | -0.3417 | No | ||
| 17 | E2F4 | ENSG00000205250.9 | 19102 | 0.062 | -0.3564 | No | ||
| 18 | JAK2 | ENSG00000096968.13 | 19235 | 0.058 | -0.3584 | No | ||
| 19 | DYRK1A | ENSG00000157540.21 | 19241 | 0.058 | -0.3572 | No | ||
| 20 | PSME2 | ENSG00000100911.16 | 19274 | 0.057 | -0.3568 | No | ||
| 21 | PSMA3 | ENSG00000100567.13 | 19401 | 0.054 | -0.3587 | No | ||
| 22 | POLE | ENSG00000177084.17 | 19403 | 0.054 | -0.3576 | No | ||
| 23 | PSMA2 | ENSG00000106588.11 | 19562 | 0.050 | -0.3603 | No | ||
| 24 | ORC2 | ENSG00000115942.9 | 19607 | 0.048 | -0.3604 | No | ||
| 25 | PSMB10 | ENSG00000205220.12 | 19937 | 0.040 | -0.3675 | No | ||
| 26 | PSMC4 | ENSG00000013275.8 | 20810 | 0.018 | -0.3884 | No | ||
| 27 | RBL2 | ENSG00000103479.16 | 20946 | 0.014 | -0.3914 | No | ||
| 28 | UBC | ENSG00000150991.15 | 20948 | 0.013 | -0.3911 | No | ||
| 29 | PSMA6 | ENSG00000100902.11 | 20976 | 0.013 | -0.3915 | No | ||
| 30 | PSMB4 | ENSG00000159377.11 | 21127 | 0.007 | -0.3950 | No | ||
| 31 | CDKN1A | ENSG00000124762.13 | 21297 | 0.004 | -0.3990 | No | ||
| 32 | AKT1 | ENSG00000142208.16 | 21695 | -0.006 | -0.4086 | No | ||
| 33 | UBB | ENSG00000170315.14 | 22145 | -0.016 | -0.4192 | No | ||
| 34 | UBA52 | ENSG00000221983.8 | 22256 | -0.020 | -0.4214 | No | ||
| 35 | PSMD3 | ENSG00000108344.15 | 23004 | -0.040 | -0.4388 | No | ||
| 36 | PSME1 | ENSG00000092010.15 | 23061 | -0.041 | -0.4393 | No | ||
| 37 | PSMA1 | ENSG00000129084.17 | 23337 | -0.048 | -0.4449 | No | ||
| 38 | PSMB9 | ENSG00000240065.8 | 23347 | -0.048 | -0.4441 | No | ||
| 39 | ORC5 | ENSG00000164815.11 | 23413 | -0.050 | -0.4446 | No | ||
| 40 | POLE3 | ENSG00000148229.13 | 23456 | -0.051 | -0.4445 | No | ||
| 41 | LIN37 | ENSG00000267796.8 | 23851 | -0.062 | -0.4528 | No | ||
| 42 | SEM1 | ENSG00000127922.9 | 24231 | -0.071 | -0.4605 | No | ||
| 43 | CUL1 | ENSG00000055130.17 | 24550 | -0.079 | -0.4665 | No | ||
| 44 | PSMB7 | ENSG00000136930.13 | 24754 | -0.084 | -0.4696 | No | ||
| 45 | RPS27A | ENSG00000143947.13 | 24801 | -0.086 | -0.4689 | No | ||
| 46 | POLA2 | ENSG00000014138.9 | 24862 | -0.087 | -0.4685 | No | ||
| 47 | PSMB1 | ENSG00000008018.9 | 25518 | -0.106 | -0.4821 | No | ||
| 48 | PSMB6 | ENSG00000142507.10 | 25718 | -0.112 | -0.4846 | No | ||
| 49 | PSMD8 | ENSG00000099341.11 | 25815 | -0.114 | -0.4844 | No | ||
| 50 | DBF4 | ENSG00000006634.8 | 25980 | -0.120 | -0.4858 | No | ||
| 51 | PSMB2 | ENSG00000126067.12 | 26219 | -0.126 | -0.4889 | No | ||
| 52 | CDK4 | ENSG00000135446.17 | 26296 | -0.129 | -0.4879 | No | ||
| 53 | HDAC1 | ENSG00000116478.12 | 26306 | -0.129 | -0.4854 | No | ||
| 54 | PSMD2 | ENSG00000175166.17 | 26310 | -0.129 | -0.4826 | No | ||
| 55 | PSMD9 | ENSG00000110801.14 | 26323 | -0.129 | -0.4801 | No | ||
| 56 | PSMA7 | ENSG00000101182.15 | 26454 | -0.134 | -0.4804 | No | ||
| 57 | PSMC1 | ENSG00000100764.14 | 26467 | -0.134 | -0.4778 | No | ||
| 58 | POLA1 | ENSG00000101868.11 | 26537 | -0.136 | -0.4765 | No | ||
| 59 | PSMF1 | ENSG00000125818.18 | 26669 | -0.140 | -0.4767 | No | ||
| 60 | PSMD4 | ENSG00000159352.15 | 26816 | -0.144 | -0.4771 | No | ||
| 61 | PPP2R2A | ENSG00000221914.11 | 27524 | -0.165 | -0.4907 | Yes | ||
| 62 | MAX | ENSG00000125952.20 | 27563 | -0.167 | -0.4881 | Yes | ||
| 63 | PSMD13 | ENSG00000185627.18 | 27620 | -0.168 | -0.4858 | Yes | ||
| 64 | PSMD11 | ENSG00000108671.11 | 27717 | -0.171 | -0.4844 | Yes | ||
| 65 | GMNN | ENSG00000112312.10 | 27728 | -0.171 | -0.4809 | Yes | ||
| 66 | PSMC5 | ENSG00000087191.13 | 27761 | -0.172 | -0.4780 | Yes | ||
| 67 | PSMB3 | ENSG00000277791.5 | 27956 | -0.179 | -0.4788 | Yes | ||
| 68 | RPA4 | ENSG00000204086.4 | 28029 | -0.182 | -0.4766 | Yes | ||
| 69 | ORC4 | ENSG00000115947.13 | 28129 | -0.185 | -0.4750 | Yes | ||
| 70 | PSMD6 | ENSG00000163636.10 | 28425 | -0.194 | -0.4780 | Yes | ||
| 71 | PSMC6 | ENSG00000100519.12 | 28449 | -0.195 | -0.4743 | Yes | ||
| 72 | SRC | ENSG00000197122.11 | 28621 | -0.200 | -0.4742 | Yes | ||
| 73 | PSMC3 | ENSG00000165916.8 | 28625 | -0.200 | -0.4699 | Yes | ||
| 74 | CCNH | ENSG00000134480.15 | 28769 | -0.204 | -0.4689 | Yes | ||
| 75 | SKP1 | ENSG00000113558.18 | 28827 | -0.206 | -0.4659 | Yes | ||
| 76 | E2F6 | ENSG00000169016.17 | 28829 | -0.206 | -0.4614 | Yes | ||
| 77 | MCM3 | ENSG00000112118.20 | 29007 | -0.212 | -0.4611 | Yes | ||
| 78 | PSMD7 | ENSG00000103035.11 | 30001 | -0.244 | -0.4800 | Yes | ||
| 79 | PSMA4 | ENSG00000041357.16 | 30107 | -0.247 | -0.4772 | Yes | ||
| 80 | E2F2 | ENSG00000007968.7 | 30138 | -0.249 | -0.4726 | Yes | ||
| 81 | CKS1B | ENSG00000173207.13 | 30473 | -0.259 | -0.4751 | Yes | ||
| 82 | LIN54 | ENSG00000189308.11 | 30719 | -0.267 | -0.4753 | Yes | ||
| 83 | CDKN2C | ENSG00000123080.12 | 30743 | -0.267 | -0.4700 | Yes | ||
| 84 | PPP2R1B | ENSG00000137713.16 | 30954 | -0.276 | -0.4692 | Yes | ||
| 85 | MCM8 | ENSG00000125885.13 | 31052 | -0.279 | -0.4655 | Yes | ||
| 86 | RPA1 | ENSG00000132383.12 | 31119 | -0.282 | -0.4610 | Yes | ||
| 87 | CABLES1 | ENSG00000134508.12 | 31130 | -0.282 | -0.4551 | Yes | ||
| 88 | CCNE1 | ENSG00000105173.14 | 32197 | -0.305 | -0.4745 | Yes | ||
| 89 | CDK2 | ENSG00000123374.11 | 32246 | -0.307 | -0.4690 | Yes | ||
| 90 | PPP2CA | ENSG00000113575.10 | 32408 | -0.314 | -0.4661 | Yes | ||
| 91 | CCND3 | ENSG00000112576.12 | 32532 | -0.317 | -0.4622 | Yes | ||
| 92 | MCM2 | ENSG00000073111.14 | 32546 | -0.318 | -0.4556 | Yes | ||
| 93 | PSMD10 | ENSG00000101843.19 | 32694 | -0.324 | -0.4522 | Yes | ||
| 94 | LIN52 | ENSG00000205659.10 | 32727 | -0.325 | -0.4459 | Yes | ||
| 95 | PSMD12 | ENSG00000197170.10 | 32756 | -0.326 | -0.4395 | Yes | ||
| 96 | RB1 | ENSG00000139687.15 | 33569 | -0.339 | -0.4519 | Yes | ||
| 97 | PPP2R1A | ENSG00000105568.18 | 34725 | -0.357 | -0.4723 | Yes | ||
| 98 | MCM6 | ENSG00000076003.5 | 34728 | -0.357 | -0.4646 | Yes | ||
| 99 | AKT3 | ENSG00000117020.18 | 35028 | -0.366 | -0.4640 | Yes | ||
| 100 | PSMB5 | ENSG00000100804.19 | 35039 | -0.367 | -0.4562 | Yes | ||
| 101 | CDKN2A | ENSG00000147889.17 | 35138 | -0.371 | -0.4506 | Yes | ||
| 102 | PSMD5 | ENSG00000095261.14 | 35294 | -0.378 | -0.4461 | Yes | ||
| 103 | MNAT1 | ENSG00000020426.11 | 35332 | -0.380 | -0.4388 | Yes | ||
| 104 | PSME3 | ENSG00000131467.11 | 35430 | -0.385 | -0.4328 | Yes | ||
| 105 | TFDP1 | ENSG00000198176.13 | 35512 | -0.389 | -0.4263 | Yes | ||
| 106 | PSMA5 | ENSG00000143106.13 | 35640 | -0.395 | -0.4208 | Yes | ||
| 107 | CDT1 | ENSG00000167513.9 | 35789 | -0.401 | -0.4157 | Yes | ||
| 108 | MCM5 | ENSG00000100297.16 | 35805 | -0.402 | -0.4074 | Yes | ||
| 109 | PSMC2 | ENSG00000161057.12 | 35948 | -0.403 | -0.4021 | Yes | ||
| 110 | ORC3 | ENSG00000135336.14 | 36389 | -0.421 | -0.4037 | Yes | ||
| 111 | PSMD14 | ENSG00000115233.12 | 36419 | -0.422 | -0.3952 | Yes | ||
| 112 | TK1 | ENSG00000167900.12 | 36493 | -0.426 | -0.3877 | Yes | ||
| 113 | RPA3 | ENSG00000106399.11 | 36661 | -0.434 | -0.3824 | Yes | ||
| 114 | PCNA | ENSG00000132646.11 | 37166 | -0.461 | -0.3847 | Yes | ||
| 115 | ORC1 | ENSG00000085840.13 | 37179 | -0.462 | -0.3749 | Yes | ||
| 116 | LIN9 | ENSG00000183814.15 | 37237 | -0.466 | -0.3662 | Yes | ||
| 117 | CCNE2 | ENSG00000175305.17 | 37360 | -0.475 | -0.3588 | Yes | ||
| 118 | RBL1 | ENSG00000080839.12 | 37521 | -0.487 | -0.3522 | Yes | ||
| 119 | POLE2 | ENSG00000100479.13 | 37582 | -0.492 | -0.3430 | Yes | ||
| 120 | PSMD1 | ENSG00000173692.13 | 37725 | -0.504 | -0.3355 | Yes | ||
| 121 | FBXO5 | ENSG00000112029.10 | 37782 | -0.511 | -0.3257 | Yes | ||
| 122 | CDK7 | ENSG00000134058.12 | 37950 | -0.524 | -0.3184 | Yes | ||
| 123 | CDC7 | ENSG00000097046.13 | 38052 | -0.531 | -0.3093 | Yes | ||
| 124 | E2F1 | ENSG00000101412.13 | 38085 | -0.533 | -0.2985 | Yes | ||
| 125 | CCNB1 | ENSG00000134057.15 | 38169 | -0.540 | -0.2889 | Yes | ||
| 126 | CCND1 | ENSG00000110092.3 | 38307 | -0.552 | -0.2802 | Yes | ||
| 127 | PRIM1 | ENSG00000198056.15 | 38325 | -0.554 | -0.2686 | Yes | ||
| 128 | PPP2CB | ENSG00000104695.13 | 38708 | -0.572 | -0.2655 | Yes | ||
| 129 | CDC45 | ENSG00000093009.10 | 38822 | -0.583 | -0.2556 | Yes | ||
| 130 | ORC6 | ENSG00000091651.9 | 38888 | -0.589 | -0.2444 | Yes | ||
| 131 | MYC | ENSG00000136997.19 | 39003 | -0.602 | -0.2341 | Yes | ||
| 132 | TOP2A | ENSG00000131747.15 | 39313 | -0.624 | -0.2281 | Yes | ||
| 133 | CDK1 | ENSG00000170312.16 | 39453 | -0.632 | -0.2177 | Yes | ||
| 134 | MYBL2 | ENSG00000101057.16 | 39815 | -0.677 | -0.2118 | Yes | ||
| 135 | PRIM2 | ENSG00000146143.19 | 39937 | -0.702 | -0.1996 | Yes | ||
| 136 | RRM2 | ENSG00000171848.15 | 39983 | -0.710 | -0.1852 | Yes | ||
| 137 | WEE1 | ENSG00000166483.11 | 40002 | -0.714 | -0.1702 | Yes | ||
| 138 | CDC6 | ENSG00000094804.12 | 40060 | -0.723 | -0.1559 | Yes | ||
| 139 | CDKN2D | ENSG00000129355.7 | 40158 | -0.743 | -0.1421 | Yes | ||
| 140 | SKP2 | ENSG00000145604.16 | 40211 | -0.755 | -0.1270 | Yes | ||
| 141 | CDC25A | ENSG00000164045.12 | 40263 | -0.768 | -0.1115 | Yes | ||
| 142 | E2F3 | ENSG00000112242.15 | 40268 | -0.769 | -0.0950 | Yes | ||
| 143 | CDK6 | ENSG00000105810.9 | 40555 | -0.858 | -0.0833 | Yes | ||
| 144 | MCM4 | ENSG00000104738.18 | 40591 | -0.872 | -0.0652 | Yes | ||
| 145 | CCNA2 | ENSG00000145386.10 | 40598 | -0.874 | -0.0464 | Yes | ||
| 146 | TYMS | ENSG00000176890.16 | 40602 | -0.877 | -0.0274 | Yes | ||
| 147 | MCM10 | ENSG00000065328.16 | 40670 | -0.907 | -0.0094 | Yes | ||
| 148 | DHFR | ENSG00000228716.7 | 40826 | -0.981 | 0.0082 | Yes |
